Maia Kaplan
University of British Columbia
Publications 2
Published on Apr 15, 2013in Journal of Immunology 4.54
Salman Ali1
Estimated H-index: 1
(University of British Columbia),
Aaron F. Hirschfeld13
Estimated H-index: 13
(University of British Columbia)
+ 20 AuthorsJin Yan3
Estimated H-index: 3
(University of British Columbia)
Respiratory diseases are the most frequent chronic illnesses in babies and children. Although a vigorous innate immune system is critical for maintaining lung health, a balanced response is essential to minimize damaging inflammation. We investigated the functional and clinical impact of human genetic variants in the promoter of NFKBIA , which encodes IκBα, the major negative regulator of NF-κB. In this study, we quantified the functional impact of NFKBIA promoter polymorphisms (rs3138053, rs223...
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