Match!
Jinsong Li
Sun Yat-sen University
SurgeryPathologyMetastasisCancer researchMedicine
45Publications
12H-index
691Citations
What is this?
Publications 46
Newest
#1Song Fan (SYSU: Sun Yat-sen University)H-Index: 13
#2Tian Tian (Nanjing Medical University)H-Index: 11
Last. Jinsong Li (SYSU: Sun Yat-sen University)H-Index: 12
view all 31 authors...
Summary Cisplatin-based neoadjuvant chemotherapy has been shown to improve survival in patients with squamous cell carcinoma (SCC), but clinical biomarkers to predict chemosensitivity remains elusive. Here, we show the long noncoding RNA (lncRNA) LINC01011, which we termed cisplatin sensitivity-associated lncRNA(CISAL), controls mitochondrial fission and cisplatin sensitivity by inhibiting BRCA1 transcription in tongue SCC (TSCC) models. Mechanistically, we found CISAL directly binds the BRCA1 p...
1 CitationsSource
#1Tian Tian (Memorial Hospital of South Bend)H-Index: 11
#2Xiaobin Lv (NCU: Nanchang University)H-Index: 1
Last. Song Fan (Harvard University)H-Index: 13
view all 20 authors...
Purpose: The overall biological roles and clinical significance of most long noncoding RNAs (lncRNA) in chemosensitivity are not fully understood. We investigated the biological function, mechanism, and clinical significance of lncRNA NR_034085, which we termed miRNA processing–related lncRNA (MPRL), in tongue squamous cell carcinoma (TSCC). Experimental Design: LncRNA expression in TSCC cell lines with cisplatin treatment was measured by lncRNA microarray and confirmed in TSCC tissues. The func...
Source
#1Sha FuH-Index: 1
#2Jinsong LiH-Index: 12
Last. Song FanH-Index: 13
view all 6 authors...
Source
#1Song Fan (Harvard University)H-Index: 13
#2Qun Xing Li (SYSU: Sun Yat-sen University)H-Index: 1
Last. Jinsong Li (SYSU: Sun Yat-sen University)H-Index: 12
view all 15 authors...
1 CitationsSource
#1Yingjuan Lu (SYSU: Sun Yat-sen University)
#2Yingru Li (SYSU: Sun Yat-sen University)H-Index: 5
Last. Jinsong Li (SYSU: Sun Yat-sen University)H-Index: 12
view all 8 authors...
Abstract Repulsive guidance molecules comprise a group of proteins that play an important role in carcinogenesis through interactions with their receptors, but their function in oral squamous cell carcinoma (OSCC) is unclear. Here, we investigated the potential role of the RGM family members in oral cancer pathogenesis. Our study showed that only RGMA was significantly downregulated in the OSCC tissues analyzed by TCGA and validated this finding in OSCC cells. The decreased expression of RGMA wa...
Source
#1Song Fan (Harvard University)H-Index: 13
#2Tian Tian (Nanjing Medical University)H-Index: 11
Last. Jinsong Li (SYSU: Sun Yat-sen University)H-Index: 12
view all 18 authors...
miRNAs that translocate from the nucleus to mitochondria are referred to as mitochondrial microRNAs (mitomiR). mitomiRs have been shown to modulate the translational activity of the mitochondrial genome, yet their role in mitochondrial DNA (mtDNA) transcription remains to be determined. Here we report that the mitomiR-2392 regulates chemoresistance in tongue squamous cell carcinoma (TSCC) cells by reprogramming metabolism via downregulation of oxidative phosphorylation and upregulation of glycol...
5 CitationsSource
#1Lehang Lin (SYSU: Sun Yat-sen University)H-Index: 1
#2Moli Huang (Soochow University (Suzhou))H-Index: 1
Last. H. Phillip Koeffler (NUS: National University of Singapore)H-Index: 86
view all 20 authors...
3 CitationsSource
#1Li Peng (SYSU: Sun Yat-sen University)H-Index: 2
#2Binyuan Jiang (MOE: Chinese Ministry of Education)H-Index: 1
Last. De-Chen Lin (SYSU: Sun Yat-sen University)H-Index: 2
view all 20 authors...
Hepatocellular carcinoma (HCC) is one of the most dominant causes of neoplasm-related deaths worldwide. In this study, we identify and characterize HCCL5, a novel cytoplasmic lncRNA, as a crucial oncogene in HCC. HCCL5 promoted cell growth, G1/S transition, invasion, and metastasis while inhibiting apoptosis of HCC cells both in vitro and in vivo. Moreover, HCCL5 was upregulated in TGF-β1-induced classical epithelial-mesenchymal transition (EMT) models, and this lncRNA in turn accelerated the EM...
12 CitationsSource
#1Song Fan (SYSU: Sun Yat-sen University)H-Index: 13
#2Han-qing ZhangH-Index: 5
Last. Jinsong Li (SYSU: Sun Yat-sen University)H-Index: 12
view all 9 authors...
Abstract Objectives A no-flap design based on actual tongue anatomy has been reported to achieve precise reconstruction, but large carcinologic tongue defects remain extremely challenging to treat. The aim of this pilot study was to explore an anatomy-based flap design for precision subtotal tongue reconstruction. Material and methods Thirty-five patients were randomly divided into two groups, a “five-points eight-line-segments” (FIPELS) technique flap design group (18 patients) and a convention...
Source
#1Weixiong ChenH-Index: 6
#2Peng WangH-Index: 6
Last. Song FanH-Index: 13
view all 23 authors...
1 CitationsSource
12345