#2Peiyong Jiang(CUHK: The Chinese University of Hong Kong)H-Index: 27
Last.Y.M. Dennis Lo(CUHK: The Chinese University of Hong Kong)H-Index: 76
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Epstein-Barr virus (EBV) is associated with a number of diseases, including malignancies. Currently, it is not known whether patients with different EBV-associated diseases have different methylation profiles of circulating EBV DNA. Through whole-genome methylation analysis of plasma samples from patients with nasopharyngeal carcinoma (NPC), EBV-associated lymphoma and infectious mononucleosis, we demonstrate that EBV DNA methylation profiles exhibit a disease-associated pattern. This observatio...
Objectives MRI can detect early-stage nasopharyngeal carcinoma (NPC), but the detection is more challenging in early-stage NPCs because they must be distinguished from benign hyperplasia in the nasopharynx. This study aimed to determine whether intravoxel incoherent motion diffusion-weighted imaging (IVIM DWI) MRI could distinguish between these two entities.
North America and Europe have been the traditional strongholds for conducting early phase clinical trials in oncology. However, the under-representation of Asians in cancer trials conducted especially in the United States (US) implies that the clinical data generated may not be generalizable to Asian patients from the rest of the world (1,2).
Purpose To determine if treatment of nasopharyngeal carcinoma (NPC) induces early changes in amide proton transfer-weighted (APTw) magnetic resonance imaging (MRI), and to perform a preliminary evaluation of APTw imaging in response assessment.