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Monica K. Silver
University of Michigan
Cord bloodAuditory brainstem responseAudiologyMedicineSensory system
15Publications
7H-index
229Citations
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Publications 21
Newest
#1Monica K. Silver (UM: University of Michigan)H-Index: 7
#2Jie Shao (ZJU: Zhejiang University)H-Index: 11
Last. John D. Meeker (UM: University of Michigan)H-Index: 54
view all 8 authors...
Abstract Introduction Despite widespread use, many herbicides and fungicides are not well studied for neurological effects. Fetal and infant brains are rapidly developing, yet the effects of early-life exposure to these classes of pesticides on visual and auditory function are unknown. Here we examined the effects of prenatal herbicide and fungicide exposure on infant grating visual acuity (VA) and auditory brainstem response (ABR). Methods 9 herbicides and 13 fungicides were measured in umbilic...
Source
#1Jaclyn M. Goodrich (UM: University of Michigan)H-Index: 15
#2Margit Burmeister (UM: University of Michigan)H-Index: 48
Last. Betsy Lozoff (UM: University of Michigan)H-Index: 45
view all 9 authors...
Abstract In a study of iron deficiency of newborns in China, children who were iron deficient or not were evaluated behaviorally and with regard to brain structure and function, demonstrating the detrimental effects of pre-and postnatal iron deficiency. We also hypothesized that iron deficiency may be exacerbated by lead and pesticides exposure. Lead, iron and 20 different pesticides were assessed in cord blood/cord serum of 1000 infants born in rural Zhejiang province. Pilot Epigenome-wide anal...
Source
#1Monica K. Silver (UM: University of Michigan)H-Index: 7
#2Aubrey L. Arain (UM: University of Michigan)H-Index: 1
Last. John D. Meeker (UM: University of Michigan)H-Index: 54
view all 7 authors...
Abstract Early-life exposure to heavy metals and/or trace metal imbalances can have negative developmental effects. Here we sought to characterize exposure profiles for 20 heavy metals and trace elements in umbilical cord blood plasma and identify demographic predictors of exposure. Twenty metals were measured in cord plasma from 357 Chinese infants using ICP-MS. Relationships between demographic variables and metals were analyzed using generalized linear models and logistic regression. Ten meta...
2 CitationsSource
#1Monica K. SilverH-Index: 7
#2Jie ShaoH-Index: 4
Last. John D. MeekerH-Index: 54
view all 6 authors...
Source
#1Monica K. SilverH-Index: 7
Last. John D. MeekerH-Index: 54
view all 7 authors...
Source
#1Monica K. Silver (UM: University of Michigan)H-Index: 7
#2Jie Shao (ZJU: Zhejiang University)H-Index: 11
Last. John D. Meeker (UM: University of Michigan)H-Index: 54
view all 11 authors...
Abstract Background Occupational studies suggest that exposure to organophosphate insecticides (OPs) can lead to vision or hearing loss. Yet the effects of early-life exposure on visual and auditory function are unknown. Here we examined associations between prenatal OP exposure and grating visual acuity (VA) and auditory brainstem response (ABR) during infancy. Methods 30 OPs were measured in umbilical cord blood using gas chromatography tandem mass spectrometry in a cohort of Chinese infants. ...
5 CitationsSource
#1Monica K. Silver (UM: University of Michigan)H-Index: 7
#2Jie Shao (ZJU: Zhejiang University)H-Index: 11
Last. John D. Meeker (UM: University of Michigan)H-Index: 54
view all 8 authors...
Abstract Background Organophosphate insecticides (OPs) are used worldwide, yet despite nearly ubiquitous exposure in the general population, few have been studied outside the laboratory. Fetal brains undergo rapid growth and development, leaving them susceptible to long-term effects of neurotoxic OPs. The objective here was to investigate the extent to which prenatal exposure to OPs affects infant motor development. Methods 30 OPs were measured in umbilical cord blood using gas chromatography ta...
15 CitationsSource
#1Monica K. SilverH-Index: 7
#2Jie ShaoH-Index: 4
Last. John D. MeekerH-Index: 54
view all 9 authors...
Introduction Occupational studies suggest that exposure to insecticides may lead to hearing loss, yet effects of early-life exposure on auditory function are unknown. We examined effects of prenata...
#1Monica K. SilverH-Index: 7
#2Jie ShaoH-Index: 4
Last. John D. MeekerH-Index: 54
view all 7 authors...
Source
#1Julie Sturza (UM: University of Michigan)H-Index: 8
#2Monica K. Silver (UM: University of Michigan)H-Index: 7
Last. John D. Meeker (UM: University of Michigan)H-Index: 54
view all 9 authors...
Abstract Background Pesticides are associated with poorer neurodevelopmental outcomes, but little is known about the effects on sensory functioning. Methods Auditory brainstem response (ABR) and pesticide data were available for 27 healthy, full-term 9-month-old infants participating in a larger study of early iron deficiency and neurodevelopment. Cord blood was analyzed by gas chromatography–mass spectrometry for levels of 20 common pesticides. The ABR forward-masking condition consisted of a c...
8 CitationsSource
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