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Wen-hua Liu
Guangzhou Medical University
Developmental psychologyPsychologyAnhedoniaSchizophreniaSocial psychology
32Publications
15H-index
552Citations
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Publications 33
Newest
#1Yi WangH-Index: 21
#2Zhi Li (CAS: Chinese Academy of Sciences)H-Index: 22
Last. Rck Chan (CAS: Chinese Academy of Sciences)H-Index: 2
view all 10 authors...
Background: Impairment in facial emotion perception is an important domain of social cognition deficits in schizophrenia. Although impaired facial emotion perception has been found in individuals with negative schizotypy (NS), little is known about the corresponding change in brain functional connectivity. Methods: Sixty-four participants were classified into a high NS group (n = 34) and a low NS group (n = 30) based on their total scores on the Chapman scales for physical and social anhedonia. ...
2 CitationsSource
#1Yi Wang (CAS: Chinese Academy of Sciences)H-Index: 21
#2Wen-hua Liu (Guangzhou Medical University)H-Index: 15
Last. Raymond C.K. Chan (CAS: Chinese Academy of Sciences)H-Index: 53
view all 4 authors...
Source
#1Wen-hua Liu (Guangzhou Medical University)H-Index: 15
#2Vincent Valton (UCL: University College London)H-Index: 7
Last. Jonathan P. Roiser (UCL: University College London)H-Index: 48
view all 5 authors...
: The lateral habenula plays a central role in reward and punishment processing and has been suggested to drive the cardinal symptom of anhedonia in depression. This hypothesis is largely based on observations of habenula hypermetabolism in animal models of depression, but the activity of habenula and its relationship with clinical symptoms in patients with depression remains unclear. High-resolution functional magnetic resonance imaging (fMRI) and computational modelling were used to investigat...
18 CitationsSource
#1Yan-yu Wang (CAS: Chinese Academy of Sciences)H-Index: 3
#2Hai-song Shi (CAS: Chinese Academy of Sciences)H-Index: 12
Last. Raymond C.K. Chan (CAS: Chinese Academy of Sciences)H-Index: 53
view all 10 authors...
The present study aimed to explore the latent structure of the 21-item Peters et al. Delusions Inventory (PDI-21) and to test the invariance of its factor structure over time and across samples. The PDI-21 was administered in two samples; one consisting of 1655 undergraduate students investigated in three waves, each separated by six months; and another consisting of 196 outpatients with schizophrenia. Exploratory factor analysis was performed to explore the internal structure of the PDI-21 base...
1 CitationsSource
#1Yi WangH-Index: 21
#2Hai-song Shi (NCEPU: North China Electric Power University)H-Index: 12
Last. Raymond C.K. Chan (CAS: Chinese Academy of Sciences)H-Index: 53
view all 14 authors...
Abstract Schizotypy is a set of personality traits that convey liability to develop schizophrenia. Studying schizotypy in healthy individuals may facilitate the understanding of the psychopathological processes underlying schizophrenia. The present study aimed to examine the developmental trajectories of schizotypy over time using a longitudinal study design. The Chapman Scales for Psychosis Proneness were administered to 1541 college students at baseline, and subsequently at six-monthly interva...
8 CitationsSource
#1Wen-hua Liu (Guangzhou Medical University)H-Index: 15
#2Vincent Valton (UCL: University College London)H-Index: 7
Last. Jonathan P. Roiser (UCL: University College London)H-Index: 48
view all 5 authors...
1 CitationsSource
#1Li-juan Shi (Hunan University of Science and Technology)H-Index: 2
#2Wen-hua Liu (Guangzhou Medical University)H-Index: 15
Last. Raymond C.K. Chan (CAS: Chinese Academy of Sciences)H-Index: 53
view all 8 authors...
Abstract Empirical findings suggest an overlap between autism spectrum disorders (ASD) and schizophrenia spectrum disorders (SSD). Co-occurring autistic and positive schizotypal traits may have a moderating effect on behaviour and cognition. This study attempted to examine the co-occurrence rate of autistic and schizotypal traits in otherwise healthy college students and to test the moderating effect of co-occurring autistic and schizotypal traits on executive function, emotion processing and so...
11 CitationsSource
#1Raymond C.K. ChanH-Index: 53
#2Diane C. GoodingH-Index: 29
Last. Eric F.C. CheungH-Index: 29
view all 12 authors...
Researchers from China and the USA show that a well-used set of psychometric tests produce reliable data across the spectrum of schizotypy. An international team of researchers led by Raymond C. K. Chan at the Chinese Academy of Sciences analyzed four Chapman psychosis-proneness scales to discern the diagnostic and statistical validity of the questionnaires between three groups representing the genetic range of schizotypy: schizophrenia patients, first-degree nonpsychotic relatives and nonclinic...
12 CitationsSource
#1Wen-hua Liu (CAS: Chinese Academy of Sciences)H-Index: 15
#2Jonathan P. Roiser (UCL: University College London)H-Index: 48
Last. Raymond C.K. Chan (CAS: Chinese Academy of Sciences)H-Index: 53
view all 9 authors...
Background: Anhedonia is a cardinal feature of major depression and is hypothesized to be driven by low motivation, in particular blunted reward sensitivity. It has been suggested to be a marker that represents a genetic predisposition to this disorder. However, little is known about the mechanisms underlying this heightened risk in unaffected first-degree relatives of patients with major depression. We previously demonstrated abnormal reward biases in acutely depressed patients. The present stu...
15 CitationsSource
#1Yi Wang (CAS: Chinese Academy of Sciences)H-Index: 21
#2Wen-hua Liu (Guangzhou Medical University)H-Index: 15
Last. Raymond C.K. Chan (CAS: Chinese Academy of Sciences)H-Index: 53
view all 11 authors...
Background. Dysregulation of the striatum and altered corticostriatal connectivity have been associated with psychotic disorders. Social anhedonia has been identified as a predictor for the development of schizophrenia spectrum disorders. The aim of the present study was to examine corticostriatal functional connectivity in individuals with high social anhedonia.
23 CitationsSource
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