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Abdelaziz El Khloufi
Free University of Brussels
11Publications
8H-index
328Citations
Publications 11
Newest
Published on Sep 1, 2010in Bulletin des Sociétés Chimiques Belges
Marcel Gielen34
Estimated H-index: 34
(Free University of Brussels),
Abdelaziz El Khloufi8
Estimated H-index: 8
(Free University of Brussels)
+ 3 AuthorsRudolph Willem38
Estimated H-index: 38
(Free University of Brussels)
Bis(di-n-butyl)(2,3,6-trifluorobenzoato)- and bis(di-n-butyl)(2,3,4,5-tetrafluorobenzoato)tin oxides were synthesized and characterized by 1H, 13C, 19F and 119Sn NMR as well as by 119mSn Mossbauer spectroscopy. They were screened in vitro against six human tumour cell lines. MCF-7 and EVSAT. breast cancers, WiDr, a colon carcinoma, IGROV, an ovarian cancer, M19 MEL, a melanoma and A498, a renal cancer.
Published on Apr 1, 1994in Organometallics4.10
François Kayser13
Estimated H-index: 13
,
Monique Biesemans34
Estimated H-index: 34
+ 7 AuthorsRudolph Willem38
Estimated H-index: 38
The crystal structure of the reaction product of the 2:3 condensation of salicylaldoxime with di-n-butyltin(IV) oxide, [(Bu2Sn)(Bu2SnO)(Bu2SnOH)(HONZO)(ONZO)], where HONZOH represents HON=CHC6H4OH (salicylaldoxime), was determined by single-crystal X-ray diffraction; it belongs to the monoclinic system, space group P2(1)/c, with a = 20.995(3) angstrom, b = 17.394(4) angstrom, c = 12.254(2) angstrom, beta = 94.43(2)degrees, and Z = 4. The compound contains two five-coordinate trigonal-bipyramidal...
Published on Jan 1, 1994in Metal-based Drugs
Marcel Gielen34
Estimated H-index: 34
,
Abdelaziz El Khloufi8
Estimated H-index: 8
+ 4 AuthorsRudolph Willem38
Estimated H-index: 38
The synthesis and spectral characterization of six novel triphenyltin compounds are described. The in vitro antitumour activity of three of these compounds against two human tumour cell lines, MCF-7, a mammary tumour, and WiDr, a colon carcinoma, was determined. All three compounds are more active than cis-platin, etoposide and doxorubicin against both tumour cell lines. They are as active as mitomycin C against WiDr, but less active against MCF-7.
Published on Oct 1, 1993in Journal of Fluorine Chemistry2.06
Marcel Gielen34
Estimated H-index: 34
(Free University of Brussels),
Monique Biesemans34
Estimated H-index: 34
(Free University of Brussels)
+ 3 AuthorsRudolph Willem38
Estimated H-index: 38
(Free University of Brussels)
The synthesis and spectroscopic characterization of diorganotin(IV) bis(difluorobenzoates) [F2C6H3COO]2SnR2 [type a] and bis[diorgano(difluorobenzoato)tin(IV)] oxides {[(F2C6H3COO)R2Sn]2O}2 [type b] are described. An X-ray structure study has revealed compound 3b, {[(2,6-F2C6H3COO)(n-C4H9)2Sn]2O}2, to be dimeric and built around a planar Sn2O2 ring. The crystals are triclinic P1BAR with the cell dimensions a=11.935(13), b=12.3675(14), c=12.974 angstrom, alpha=92.89(8), beta=84.32(7), gamma=67.49...
Published on Sep 1, 1993in Applied Organometallic Chemistry3.26
Rudolph Willem38
Estimated H-index: 38
(Free University of Brussels),
Monique Biesemans34
Estimated H-index: 34
(Free University of Brussels)
+ 3 AuthorsMarcel Gielen34
Estimated H-index: 34
(ULB: Université libre de Bruxelles)
The synthesis and characterization of tetraethylammonium (diorgano)halogeno(2, 6‐pyridinedicarboxylato)stannates are described. The solution structures of these complexes in CDCl3 and DMSO are discussed on the basis of 119Sn and 19F NMR data. Their in vitro antitumour activities against two human tumour cell lines, MCF‐7 and WiDr, are presented. Copyright © 1993 John Wiley & Sons, Ltd.
Published on Apr 1, 1993in Applied Organometallic Chemistry3.26
Marcel Gielen34
Estimated H-index: 34
(Free University of Brussels),
Abdelaziz El Khloufi8
Estimated H-index: 8
(Free University of Brussels)
+ 1 AuthorsRudolph Willem38
Estimated H-index: 38
(Free University of Brussels)
The di-n-butyltin(IV) and diethyltin(IV) fluorobenzoates [FC6H4COO]2SnR2 and (FC6H4COOR2Sn)2O have been synthesized and characterized spectroscopically. Their in vitro antitumor activity against two human tumor cell lines, MCF-7, a mammary tumor, and WiDr, a colon carcinoma, as well as against the NCI cell panel, is satisfactory.
Published on Jan 1, 1992in Polyhedron2.28
Marcel Gielen34
Estimated H-index: 34
(Free University of Brussels),
Abdelaziz El Khloufi8
Estimated H-index: 8
(Free University of Brussels)
+ 2 AuthorsJacqueline Meunier-Piret2
Estimated H-index: 2
(Catholic University of Leuven)
The X-ray crystal structures of [diethyl(2-methylthio-3-pyridinecarboxylato)tin] oxide (1a) and diethyltin bis(2-methylthio-3-pyridinecarboxylate) (1b) were determined. Compound 1a is a centrosymmetric dimer with two distinct types of carboxylate moieties and tin atoms with trigonal bipyramidal geometries. Compound 1b is monomeric with a six-coordinate tin atom and two equivalent carboxylate groups chelating the tin atom. Compounds 2a and 2b, the di-n-butyl analogues of 1a and 1b, have also been...
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