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Stephanie H. Lim
University of New South Wales
36Publications
10H-index
239Citations
Publications 38
Newest
#2Margaret Lee (WEHI: Walter and Eliza Hall Institute of Medical Research)H-Index: 4
Last.Gary RichardsonH-Index: 13
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#1Sumal Fernando (UNSW: University of New South Wales)
#2Michael Lin (UNSW: University of New South Wales)H-Index: 11
Last.Stephanie H. Lim (UNSW: University of New South Wales)H-Index: 10
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Objective:This study explored the value of serial 18-fludeoxyglucose-positron emission tomography (18F-FDG-PET/CT) in predicting disease-free survival (DFS) in locally advanced rectal cancer (LARC)...
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#1Stephanie H. LimH-Index: 10
#2Emilia IpH-Index: 1
Last.M. T. KingH-Index: 46
view all 11 authors...
Aims: There is limited data on health-related quality of life (HRQoL) in locally advanced rectal cancer. We assessed HRQoL before, during and after neoadjuvant chemoradiation, correlated this to corresponding clinician-reported adverse events (CR-AEs) and explored disparities between patients of Asian ethnicity versus Caucasians. Correlation between HRQoL and treatment response was also assessed. Methods: A consecutive sample of patients was recruited. HRQoL was assessed with the EORTC QLQ-C30 b...
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#1Sayeda K Naher (UNSW: University of New South Wales)
#2Shamsudheen Padinharakam (UNSW: University of New South Wales)
Last.Stephanie H. Lim (UNSW: University of New South Wales)H-Index: 10
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Abstract Background Non–clear-cell renal cell carcinoma (nccRCC) and renal cell carcinoma with sarcomatoid features (scRCC) are rare, and represent subtypes with less defined treatment strategies. The aim of this study is to describe the patterns of care and outcomes of these patients in 2 tertiary referral centers in South Western Sydney Local Health District over a 10-year period. Patients and Methods Patients with RCC seen at South Western Sydney Local Health District from January 1, 2005 to ...
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#1Hui-Li Wong (WEHI: Walter and Eliza Hall Institute of Medical Research)H-Index: 11
#2Koen Degeling (University of Melbourne)
Last.Peter Gibbs (WEHI: Walter and Eliza Hall Institute of Medical Research)H-Index: 45
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e18061Background: The wide range of possible combinations and sequences available for mCRC treatment presents a major challenge to clinicians, who need to determine the optimal approach for an indi...
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#1Hui-Li WongH-Index: 11
#2K DegelingH-Index: 2
Last.Peter GibbsH-Index: 45
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#1Sharlyn Kang (UOW: University of Wollongong)H-Index: 1
Last.Stephanie H. LimH-Index: 10
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678Background: There is limited information on outcomes in elderly patients with rectal cancer as they are often excluded from clinical trials. This study aimed to assess treatment patterns and outcomes in these patients. Methods: We utilised data from electronic records to identify patients aged ≥ 70 years with a histological diagnosis of rectal cancer from 2006-2015, treated in the South Western Sydney and Illawarra Shoalhaven Local Health Districts, Australia. Treatment modalities, recurrence...
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#2Sharlyn Kang (UOW: University of Wollongong)H-Index: 1
Last.Daniel Brungs (UOW: University of Wollongong)H-Index: 3
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675Background: Consensus international guidelines recommend the use of neoadjuvant chemo-radiotherapy in patients with stage II-III rectal cancer. Despite this, due to factors including inaccurate/under-staging, patient co-morbidities and acute presentations, a proportion will undergo up-front surgical resection. The survival benefit of adjuvant therapy is unclear in this real world, non-trial population. Methods: A retrospective analysis of patients presenting with stage II-III rectal adenocarc...
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#1Vincent T. Ho (USYD: University of Sydney)H-Index: 71
#2Liping Chung (USYD: University of Sydney)H-Index: 3
Last.C. Soon LeeH-Index: 39
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The MRE11/RAD50/NBS1 (MRN) complex plays an essential role in detecting and repairing double-stranded breaks, and thus the potential roles of MRE11, RAD50 and NBS1 proteins in the pathogenesis of various cancers is the subject of investigation. This study was aimed at assessing the three-protein panel of MRN complex subunits as a potential radiosensitivity marker and evaluating the prognostic and clinicopathological implications of MRN expression in rectal cancer. Samples from 265 rectal cancer ...
4 CitationsSource
#1Vincent T. HoH-Index: 71
#2Liping ChungH-Index: 3
Last.C. Soon LeeH-Index: 39
view all 12 authors...
Background: Molecular biomarkers have the potential to predict response to the treatment of rectal cancer. In this study, we aimed to evaluate the prognostic and clinicopathological implication of RAD50 (DNA repair protein RAD50 homolog) expression in rectal cancer. Methods: A total of 266 rectal cancer patients who underwent surgery and received chemo- and radiotherapy between 2000 and 2011 were involved in the study. Postoperative RAD50 expression was determined by immunohistochemistry in surg...
2 CitationsSource
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