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Gareth I. Davies
Swansea University
PediatricsMedical prescriptionPregnancyPopulationMedicine
8Publications
3H-index
158Citations
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Publications 9
Newest
#1JordanSue (Swansea University)H-Index: 31
#2Gareth I. Davies (Swansea University)H-Index: 3
Last. Ioan Humphreys (Swansea University)H-Index: 10
view all 5 authors...
Objectives To explore associations between exposure to antidepressants, their discontinuation, depression [medicated or unmediated] and preterm birth [<37 and <32 weeks], small for gestational age (SGA) [<10th and <3rd centiles], breastfeeding [any] at 6–8 weeks. Methods Design: A population-based cohort study. Setting: The Secure Anonymised Information Linkage [SAIL] databank in Wales, linking maternal primary care data with infant outcomes. Participants: 107,573, 105,331, and 38,725 infants bo...
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#1Simon Sawhney (Aberd.: University of Aberdeen)H-Index: 9
#2Heather A. Robinson (MAHSC: Manchester Academic Health Science Centre)H-Index: 3
Last. Corrinda Black (Aberd.: University of Aberdeen)H-Index: 4
view all 17 authors...
Objectives A rapid growth in the reported rates of acute kidney injury (AKI) has led to calls for greater attention and greater resources for improving care. However, the reported incidence of AKI also varies more than tenfold between previous studies. Some of this variation is likely to stem from methodological heterogeneity. This study explores the extent of cross-population variation in AKI incidence after minimising heterogeneity. Design Population-based cohort study analysing data from elec...
1 CitationsSource
#1Thinzar Min (Swansea University)H-Index: 3
#2Gareth I. Davies (Swansea University)H-Index: 3
Last. Jeffrey W. Stephens (Swansea University)H-Index: 30
view all 5 authors...
Abstract Aims Chronic kidney disease (CKD) is common in type 2 diabetes and limits the treatment choices for glycaemic control. Our aim was to examine real-world prescribing for managing hyperglycaemia in the presence of CKD. Methods The SAIL (Secure Anonymised Information Linkage) databank was used to examine prescribing during the period from the 1st of January to 30th December 2014. CKD was defined as:- none or mild CKD, eGFR ≥60 mL/min/1.73m2; moderate CKD eGFR Results We identified 9585 sub...
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#1JordanSue (Swansea University)H-Index: 31
#2Joan K. Morris (QMUL: Queen Mary University of London)H-Index: 51
Last. Helen Dolk (Ulster University)H-Index: 52
view all 13 authors...
Background Hypothesised associations between in utero exposure to selective serotonin reuptake inhibitors (SSRIs) and congenital anomalies, particularly congenital heart defects (CHD), remain controversial. We investigated the putative teratogenicity of SSRI prescription in the 91 days either side of first day of last menstrual period (LMP). Methods and Findings Three population-based EUROCAT congenital anomaly registries- Norway (2004–2010), Wales (2000–2010) and Funen, Denmark (2000–2010)—were...
16 CitationsSource
#1Ester GarneH-Index: 30
#2A Vinkel HansenH-Index: 1
Last. Helen Dolk (Ulster University)H-Index: 52
view all 11 authors...
Objective To examine the effect of maternal exposure to asthma medications on the risk of congenital anomalies. Design Meta-analysis of aggregated data from three cohort studies. Setting Linkage between healthcare databases and EUROCAT congenital anomaly registries. Population 519 242 pregnancies in Norway (2004–2010), Wales (2000–2010) and Funen, Denmark (2000–2010). Methods Exposure defined as having at least one prescription for asthma medications issued (Wales) or dispensed (Norway, Denmark)...
7 CitationsSource
#1Rachel Charlton (University of Bath)H-Index: 11
#2Kari Klungsøyr (FHI: Norwegian Institute of Public Health)H-Index: 25
Last. Ester GarneH-Index: 30
view all 19 authors...
Aim To explore antidiabetic medicine prescribing to women before, during and after pregnancy in different regions of Europe.
133 CitationsSource
#1JordanSue (Swansea University)H-Index: 31
#2Rachel Charlton (University of Bath)H-Index: 11
Last. S. Man (UCL: University College London)H-Index: 1
view all 21 authors...
Objective / Background Use of selective serotonin reuptake inhibitors (SSRIs) during pregnancy has been associated with adverse pregnancy outcomes, including congenital heart disease. Objectives: To describe utilisation patterns of SSRIs 1 year before, during and 1 year after pregnancy in primary care in Wales and 5 other European databases. Methods A common protocol was implemented across 6 databases in: Denmark, The Netherlands, Tuscany, Emilia Romagna, Wales, and the Clinical Practice Researc...
1 CitationsSource
#1JordanSueH-Index: 31
#2Rachel CharltonH-Index: 11
Last. S. ManH-Index: 1
view all 21 authors...
Source
#1JordanSue (Swansea University)H-Index: 31
#2Rachel Charlton (University of Bath)H-Index: 11
Last. Helen Dolk (Ulster University)H-Index: 52
view all 19 authors...
Objective / Background 1) animal studies are seriously limited in their ability to predict human teratogenesis. 2) pregnant women are excluded from pre-marketing clinical trials in humans. Aims In EURO medi CAT we aim to build a European system for reproductive safety evaluation: To identify systematically and comprehensively the possible adverse effects in pregnancy of drugs at the earliest possible stage post marketing. To monitor and evaluate European safety measures. Methods EURO medi CAT wi...
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