Simon G. Thompson
University of Cambridge
Publications 366
#1Stephen KaptogeH-Index: 50
Last.Jenny DonovanH-Index: 79
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Summary Background The INTERVAL trial showed that, over a 2-year period, inter-donation intervals for whole blood donation can be safely reduced to meet blood shortages. We extended the INTERVAL trial for a further 2 years to evaluate the longer-term risks and benefits of varying inter-donation intervals, and to compare routine versus more intensive reminders to help donors keep appointments. Methods The INTERVAL trial was a parallel group, pragmatic, randomised trial that recruited blood donors...
#1Lisa Pennells (University of Cambridge)H-Index: 13
#2Stephen Kaptoge (University of Cambridge)H-Index: 50
Last.Karel G. M. Moons (UU: Utrecht University)H-Index: 77
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AIMS: There is debate about the optimum algorithm for cardiovascular disease (CVD) risk estimation. We conducted head-to-head comparisons of four algorithms recommended by primary prevention guidelines, before and after 'recalibration', a method that adapts risk algorithms to take account of differences in the risk characteristics of the populations being studied. METHODS AND RESULTS: Using individual-participant data on 360 737 participants without CVD at baseline in 86 prospective studies from...
#1John Gregson (Lond: University of London)H-Index: 16
#2Stephen Kaptoge (University of Cambridge)H-Index: 50
Last.Christopher Kabrhel (Harvard University)H-Index: 24
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Importance: It is uncertain to what extent established cardiovascular risk factors are associated with venous thromboembolism (VTE). Objective: To estimate the associations of major cardiovascular risk factors with VTE, ie, deep vein thrombosis and pulmonary embolism. Design, Setting, and Participants: This study included individual participant data mostly from essentially population-based cohort studies from the Emerging Risk Factors Collaboration (ERFC; 731 728 participants; 75 cohorts; years ...
#1Michael Sweeting (University of Cambridge)H-Index: 33
#2Pinar Ulug (Imperial College London)H-Index: 10
Last.Janet T. Powell (Imperial College London)H-Index: 61
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Background: The aim of this study was to develop a 48-h mortality risk score, which included morphology data, for patients with ruptured abdominal aortic aneurysm presenting to an emergency department, and to assess its predictive accuracy and clinical effectiveness in triaging patients to immediate aneurysm repair, transfer or palliative care. Methods: Data from patients in the IMPROVE (Immediate Management of the Patient With Ruptured Aneurysm: Open Versus Endovascular Repair) randomized trial...
#1Simon G. Thompson (University of Cambridge)H-Index: 95
#2Matthew J. Bown (University of Leicester)H-Index: 34
Last.Michael Sweeting (University of Cambridge)H-Index: 33
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#1Michael Sweeting (University of Cambridge)H-Index: 33
#2Katya L. Masconi (University of Cambridge)H-Index: 5
Last.Simon G. Thompson (University of Cambridge)H-Index: 95
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The UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) programme commissioned this research (project number 14/179/01).