Match!
Maleeha Mashiatulla
Rush University Medical Center
AnatomyTomographyCortical boneBiologyCoefficient of variation
4Publications
3H-index
20Citations
What is this?
Publications 6
Newest
#1B. M. Wilson (Rush University Medical Center)H-Index: 1
#2Meghan M. Moran (Rush University Medical Center)H-Index: 4
Last. Dale R. SumnerH-Index: 47
view all 7 authors...
Source
#1Frank C. Ko (Rush University Medical Center)
#2Matthew J. Meagher (Rush University Medical Center)H-Index: 1
Last. Dale R. Sumner (Rush University Medical Center)H-Index: 47
view all 6 authors...
Source
#1Maleeha Mashiatulla (UIC: University of Illinois at Chicago)H-Index: 3
#2Ryan D. Ross (Rush University Medical Center)H-Index: 13
Last. D. Rick Sumner (UIC: University of Illinois at Chicago)H-Index: 12
view all 3 authors...
Abstract Changes in the bone mineral density distribution (BMDD), due to disease or drugs, can alter whole bone mechanical properties such as strength, stiffness and toughness. The methods currently available for assessing BMDD are destructive and two-dimensional. Micro-computed tomography (μCT) has been used extensively to quantify the three-dimensional geometry of bone and to measure the mean degree of mineralization, commonly called the tissue mineral density (TMD). The TMD measurement has be...
3 CitationsSource
Articular cartilage lines the load-bearing surfaces of long bones and undergoes compositional and structural degeneration during osteoarthritis progression. Contrast enhanced microcomputed tomography (μCT) is being applied to a variety of preclinical models, including the mouse, to map structural and compositional properties in 3-D. The thinness (˜30-50 μm) and high cellularity of mouse articular cartilage presents a significant imaging challenge. Our group previously showed that mouse articular...
7 CitationsSource
#1Ryan D. Ross (Rush University Medical Center)H-Index: 13
#2Maleeha Mashiatulla (UIC: University of Illinois at Chicago)H-Index: 3
Last. D. Rick Sumner (UIC: University of Illinois at Chicago)H-Index: 12
view all 7 authors...
The G171V mutation in the low-density lipoprotein receptor-related protein 5 (LRP5) leads to a high bone mass (HBM) phenotype. Studies using HBM transgenic mouse models have consistently found increased bone mass and whole-bone strength, but little attention has been paid to the composition of the bone matrix. The current study sought to determine if the cortical bone matrix composition differs in HBM and wild-type mice and to determine how much of the variance in bone material properties is exp...
3 CitationsSource
#1Ryan D. Ross (Rush University Medical Center)H-Index: 13
#2Maleeha Mashiatulla (UIC: University of Illinois at Chicago)H-Index: 3
Last. D. Rick Sumner (UIC: University of Illinois at Chicago)H-Index: 12
view all 5 authors...
Sclerostin and parathyroid hormones are strong negative and positive regulators of bone formation, respectively. The anabolic response induced by intermittent (iPTH) treatment is sclerostin status-dependent. However, the interaction between sclerostin and iPTH at the matrix level is unknown. The goal of the current study was to determine if iPTH treatment affects matrix composition and, if so, whether these effects are dependent on sclerostin status. Humeral trabecular and cortical bone sites fr...
7 CitationsSource
1