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H. Kitchen
Adelphi University
Intensive care medicinePhysical therapyPatient-reported outcomeClinical trialMedicine
34Publications
6H-index
134Citations
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Publications 41
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#1H. KitchenH-Index: 6
Last. Vipul Jairath (London Health Sciences Centre)H-Index: 1
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#1K.W. Wyrwich (Eli Lilly and Company)H-Index: 1
#2H. KitchenH-Index: 6
Last. Brett A. King (Yale University)H-Index: 16
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BACKGROUND: Valid patient-reported outcome (PRO) measures are required to evaluate alopecia areata (AA) treatments. OBJECTIVES: To develop a content-valid and clinically meaningful PRO measure to assess AA scalp hair loss with scores comparable to the 5-response level AA Investigator Global Assessment (AA-IGA). METHODS: A draft PRO measure was developed based on input from 10 AA clinical experts. The PRO measure was cognitively debriefed, modified, and finalized through two rounds of qualitative...
1 CitationsSource
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#1K.W. Wyrwich (Eli Lilly and Company)H-Index: 1
#2H. KitchenH-Index: 6
Last. Brett A. King (Yale University)H-Index: 16
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BACKGROUND: Content valid and clinically meaningful instruments are required to evaluate outcomes of therapeutic interventions in alopecia areata (AA). OBJECTIVE: To develop an investigator global assessment (IGA) to interpret treatment response in AA treatment studies. METHODS: Qualitative interviews were conducted in the US with expert dermatologists and AA patients who had experienced >/=50% scalp hair loss. Thematic data analysis identified critical outcomes and evaluated the content validit...
3 CitationsSource
Last. H. KitchenH-Index: 6
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#2Natalie AldhouseH-Index: 1
Last. H. KitchenH-Index: 6
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#1Andrew TriggH-Index: 2
#2Eric Chan (Janssen Pharmaceutica)H-Index: 1
Last. Jane Scott (Janssen Pharmaceutica)H-Index: 12
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#1Joseph M. Herman (Johns Hopkins University)H-Index: 55
#2H. KitchenH-Index: 6
Last. Claire Johnson Dc MSEd (University of Southampton)H-Index: 39
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Purpose Pancreatic cancer and its treatments impact patients’ symptoms, functioning, and quality of life. Content-valid patient-reported outcome (PRO) instruments are required to assess outcomes in clinical trials. This study aimed to: (a) conceptualise the patient experience of pancreatic cancer; (b) identify relevant PRO instruments; (c) review the content validity of mapped instruments to guide PRO measurement in clinical trials.
1 CitationsSource
#1Arnold Degboe (AstraZeneca)H-Index: 1
#2Sarah L. KnightH-Index: 1
Last. Simon N. RogersH-Index: 1
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Head and neck squamous cell carcinoma (HNSCC) and its associated treatments may affect all aspects of patients’ health-related quality of life (HRQoL). Although the EORTC QLQ-HN patient quotes were coded to identify concepts and themes to develop a conceptual model of HNSCC experience. Fourteen patients were interviewed (71% male, aged 35–84 years). Patients reported few symptoms pre-diagnosis including neck lump/swelling (n = 7/14, 50%) and/or difficulty swallowing (n = 3/14, 21%). Treatments g...
1 CitationsSource
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