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Marina MacLean
University of Nevada, Reno
5Publications
5H-index
115Citations
Publications 5
Newest
#1Marina MacLean (UNR: University of Nevada, Reno)H-Index: 5
#2Jeffrey A. Nadeau (UNR: University of Nevada, Reno)H-Index: 3
Last.Gary J. Blomquist (UNR: University of Nevada, Reno)H-Index: 50
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Abstract Hydrocarbon biosynthesis in insects involves the elongation of fatty acyl-CoAs to very-long chain fatty acyl-CoAs that are then reduced and converted to hydrocarbon, with the last step involving the oxidative decarbonylation of an aldehyde to hydrocarbon and carbon dioxide. Cytochromes P450 in the 4G family decarbonylate aldehydes to hydrocarbon. All insect acyl-CoA reductases studied to date reduce fatty acyl-CoAs to alcohols. The results of the work reported herein demonstrate that CY...
10 CitationsSource
#1Bernarda Calla (UIUC: University of Illinois at Urbana–Champaign)H-Index: 11
#2Marina MacLean (UNR: University of Nevada, Reno)H-Index: 5
Last.May R. Berenbaum (UIUC: University of Illinois at Urbana–Champaign)H-Index: 69
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6 CitationsSource
#1Jeffrey A. Nadeau (UNR: University of Nevada, Reno)H-Index: 3
#2Juli Petereit (UNR: University of Nevada, Reno)H-Index: 5
Last.Claus Tittiger (UNR: University of Nevada, Reno)H-Index: 24
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Abstract Background The mountain pine beetle (MPB, Dendroctonus ponderosae Hopkins) is a highly destructive pest of pine forests in western North America. During flight to a new host tree and initiation of feeding, mountain pine beetles release aggregation pheromones. The biosynthetic pathways of these pheromones are sex-specific and localized in the midgut and fat body, but the enzymes involved have not all been identified or characterized. Results We used a comparative RNA-Seq analysis between...
12 CitationsSource
#1Vasileia Balabanidou (FORTH: Foundation for Research & Technology – Hellas)H-Index: 4
#2Anastasia Kampouraki (UoC: University of Crete)H-Index: 4
Last.John Vontas (FORTH: Foundation for Research & Technology – Hellas)H-Index: 42
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The role of cuticle changes in insecticide resistance in the major malaria vector Anopheles gambiae was assessed. The rate of internalization of 14C deltamethrin was significantly slower in a resistant strain than in a susceptible strain. Topical application of an acetone insecticide formulation to circumvent lipid-based uptake barriers decreased the resistance ratio by ∼50%. Cuticle analysis by electron microscopy and characterization of lipid extracts indicated that resistant mosquitoes had a ...
72 CitationsSource
#1Minmin Song (UNR: University of Nevada, Reno)H-Index: 4
#2Amy C. Kim (UNR: University of Nevada, Reno)H-Index: 1
Last.Claus Tittiger (UNR: University of Nevada, Reno)H-Index: 24
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Abstract Ips pini bark beetles use myrcene hydroxylases to produce the aggregation pheromone component, ipsdienol, from myrcene. The enantiomeric ratio of pheromonal ipsdienol is an important prezygotic mating isolation mechanism of I. pini and differs among geographically distinct populations. We explored the substrate and product ranges of myrcene hydroxylases ( CYP9T2 and CYP9T3 ) from reproductively-isolated western and eastern I. pini . The two cytochromes P450 share 94% amino acid identity...
15 CitationsSource
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