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Turki Al Hagbani
University of Louisiana at Monroe
MasticationChemistryGum baseChewinessChromatography
7Publications
2H-index
17Citations
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Publications 7
Newest
#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
#2Mohammad M. Kamal (ULM: University of Louisiana at Monroe)H-Index: 3
Last. Sami Nazzal (TTUHSC: Texas Tech University Health Sciences Center)H-Index: 22
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AbstractObjective: Developing chewing gum tablets (CGTs) with high drug loads is a challenge due to the loss of mastication properties. We postulated that poor mastication properties of such gums c...
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#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
Last. Sami Nazzal (ULM: University of Louisiana at Monroe)H-Index: 22
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Abstract Curcumin (CUR) chewing gums have potential therapeutic benefits to head and neck cancer patients. The objective of this work was to develop medicated chewing gums (MCGs) with high CUR loading and desirable mastication properties. This was accomplished by evaluating the effect of five gum ingredients: (X1) polyisobutene, (X2) polyvinyl acetate, (X3) wood rosin, (X4) wax, and (X5) CUR on the mechanical properties of the MCGs using a 25-run, five-factor, two-level D-Optimal mixture design....
1 CitationsSource
#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
Last. Sami Nazzal (ULM: University of Louisiana at Monroe)H-Index: 22
view all 4 authors...
Curcumin chewing gums could be therapeutically beneficial if used by the head and neck cancer patients. High curcumin loading in chewing gums however is needed to achieve desired therapeutic effect. Preparing gums with high drug load is nonetheless challenging because of the negative impact of solids on their masticatory properties. The use of liquid flavors was found to partially solve this problem. The objectives of this study were to (1) determine the maximum amount of curcumin that can be lo...
2 CitationsSource
#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
#2Sami Nazzal (ULM: University of Louisiana at Monroe)H-Index: 22
Medicated chewing gums (MCGs) represent a unique platform for drug delivery. They have been defined as solid single-dose preparations, which may contain more than one active pharmaceutical ingredient (API) with base consisting primarily of gum that has to be chewed for a certain period of time. They mainly contain a tasteless masticatory gum base as the core with other minor nonmasticatory ingredients, such as flavors and sweeteners. Despite their advantages in drug delivery, MCGs remain a niche...
1 CitationsSource
#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
#2Sami Nazzal (TMU: Taipei Medical University)H-Index: 22
Abstract One approach to enhance curcumin (CUR) aqueous solubility is to use cyclodextrins (CDs) to form inclusion complexes where CUR is encapsulated as a guest molecule within the internal cavity of the water-soluble CD. Several methods have been reported for the complexation of CUR with CDs. Limited information, however, is available on the use of the autoclave process (AU) in complex formation. The aims of this work were therefore to (1) investigate and evaluate the AU cycle as a complex for...
7 CitationsSource
#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
#2Michael A. Veronin (UT Tyler: University of Texas at Tyler)H-Index: 1
Last. Sami Nazzal (TMU: Taipei Medical University)H-Index: 22
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There is an ongoing need for new or alternate approaches to distinguish between innovative pharmaceutical products from counterfeit or visually similar medicines. In this study we hypothesized that the quantitative measurement of the color on the surface of tablets, using the CIE L∗a∗b∗ color space, might be used to accomplish this objective. Several proof-of-concept studies were carried out in which ColorQuest XE colorimeter was used to measure the tristimulus L∗, a∗, and b∗ color values from t...
4 CitationsSource
#1Turki Al Hagbani (ULM: University of Louisiana at Monroe)H-Index: 2
#2Mohammad T. H. Nutan (A&M: Texas A&M University)H-Index: 7
Last. Sami Nazzal (ULM: University of Louisiana at Monroe)H-Index: 22
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There is an ongoing need for new or alternate approaches to identify innovative pharmaceutical products and distinguish them from counterfeit medicines. In this study we present data that demonstrate how quantitative measurement of the color on the surface of tablets could be used to accomplish this objective. Several proof-of-concept studies were performed in which ColorQuest XE colorimeter was used to measure the tristimulus L*, a*, and b* color values from the surface of pharmaceutical tablet...
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