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Monika Michaelis
Nottingham Trent University
6Publications
2H-index
27Citations
Publications 6
Newest
Published on Mar 1, 2019in Bioinspired, biomimetic and nanobiomaterials 0.78
CarmonaDaniel (University of Bremen), TreccaniLaura + 5 AuthorsMaasMichael (University of Bremen)
The iron storage protein ferritin is well known for its ability to mineralize iron oxides in its interior cavity. In this study, the authors investigated the mineralization behavior of H and L ferr...
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Published on Jan 1, 2019in Physical Chemistry Chemical Physics 3.91
Daniel Oliver1
Estimated H-index: 1
(NTU: Nottingham Trent University),
Monika Michaelis2
Estimated H-index: 2
(NTU: Nottingham Trent University)
+ 2 AuthorsCarole C. Perry44
Estimated H-index: 44
(NTU: Nottingham Trent University)
Polypeptide based biosilica composites show promise as next generation multi-functional nano-platforms for diagnostics and bio-catalytic applications. Following the identification of a strong silica binder (LDHSLHS) by phage display, we conduct structural analysis of the polypeptide at the interface with amorphous silica nanoparticles in an aqueous environment. Our approach relies on modelling infrared and Raman spectral responses using predictions of molecular dynamics simulations and quantum s...
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Published on Dec 10, 2018in ACS Biomaterials Science & Engineering 4.43
Nils Hildebrand3
Estimated H-index: 3
(University of Bremen),
Monika Michaelis2
Estimated H-index: 2
(University of Bremen)
+ 9 AuthorsSusan Köppen12
Estimated H-index: 12
(University of Bremen)
Adsorption of enzymes on solid surfaces may lead to conformational changes that reduce their catalytic conversion activity and are thus detrimental to the efficiency of biotechnology or biosensing applications. This work is a joint theoretical and experimental endeavor in which we identify and quantify the conformational changes that chymotrypsin undergoes when in contact with the surface of amorphous silica nanoparticles. For this purpose, we use circular dichroism spectroscopy, standard molecu...
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Published on Jul 17, 2018in Langmuir 3.79
Anna Sola-Rabada3
Estimated H-index: 3
(NTU: Nottingham Trent University),
Monika Michaelis2
Estimated H-index: 2
(NTU: Nottingham Trent University)
+ 4 AuthorsCarole C. Perry44
Estimated H-index: 44
(NTU: Nottingham Trent University)
In this contribution, the effect of silica particle size (28 and 210 nm) and surface chemistry (i.e., hydroxyl, methyl, or amino groups) on peptide binding response is studied with a specific emphasis on the effect of the extent of functionalization on binding. Exhaustive characterization of the silica surfaces was crucial for knowledge of the chemistry and topography of the solid surface under study and, thus, to understand their impact on adsorption and the conformational ensemble of the pepti...
1 Citations Source Cite
Published on Jan 30, 2018in Journal of Natural Products 3.88
Fakir Shahidullah Tareq8
Estimated H-index: 8
(University of Bremen),
Choudhury M. Hasan17
Estimated H-index: 17
(DU: University of Dhaka)
+ 7 AuthorsPeter Spiteller19
Estimated H-index: 19
(University of Bremen)
Three new and seven known calopins were isolated from Caloboletus radicans. The structures of the new cyclocalopins, 8-deacetylcyclocalopin B (1), cyclocalopin A-15-ol (2), and 12,15-dimethoxycyclocalopin A (3), were mainly elucidated by NMR and MS data analysis. The stereochemistry of 1–3 was assigned based on NOE correlations and coupling constants and by comparison of their CD spectra with those of similar known calopins. While 1–10 were inactive against two cancer cell lines, they displayed ...
1 Citations Source Cite
Published on Apr 18, 2017in Environmental Science & Technology 6.65
Monika Michaelis2
Estimated H-index: 2
,
Cornelius Fischer17
Estimated H-index: 17
+ 1 AuthorsAndreas Luttge31
Estimated H-index: 31
Zinc oxide (ZnO) is of widespread use for numerous applications, including many in the cosmetic industry. Thus, ZnO particles are quite likely to enter the environment. ZnO may be harmful because of the release of cytotoxic Zn2+ ions during dissolution reactions. Here, we analyze the dissolution kinetics of the polar zinc-terminated (000–1) and nonpolar (10–10) crystal surfaces in ultrapure water to examine the impact of the crystal defects on dissolution. By using a complementary approach of at...
8 Citations Source Cite
Published on Jan 1, 2015in Analyst 3.86
Qing Li9
Estimated H-index: 9
(University of Bremen),
Monika Michaelis2
Estimated H-index: 2
(University of Bremen)
+ 1 AuthorsLucio Colombi Ciacchi20
Estimated H-index: 20
(University of Bremen)
We have developed a novel aptasensor based on single-molecule force spectroscopy (SMFS) capable of detecting mercury ions (Hg2+) with sub-nM sensitivity. The single-strand (ss) DNA aptamer used in this work is rich in thymine (T) and readily forms T–Hg2+–T complexes in the presence of Hg2+. The aptamer was conjugated to an atomic force microscope (AFM) probe, and the adhesion force between the probe and a flat graphite surface was measured by single-molecule force spectroscopy (SMFS). The presen...
17 Citations Source Cite
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