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Lorena Incorvaia
University of Palermo
76Publications
11H-index
410Citations
Publications 84
Newest
#1Deborah Cosentini (University of Brescia)H-Index: 3
#2Giuseppe Badalamenti (University of Palermo)H-Index: 19
Last.Alfredo Berruti (University of Brescia)H-Index: 49
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Abstract Background Surgery represents the best treatment for primary gastrointestinal stromal tumors (GISTs). The aim of this study is to analyse outcomes of surgical management in order to evaluate the influence of microscopically R1 margins on survival and recurrence in patients affected by GISTs. Methods The study reviewed retrospective data from 74 patients surgically treated for primary GISTs without metastasis at diagnosis. Clinical and pathological findings, surgical procedures, informat...
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Long noncoding RNAs (lncRNAs) are emerging as key regulators of genetic and epigenetic networks, and their deregulation may underlie complex diseases, such as carcinogenesis. Several studies described lncRNA alterations in patients with solid tumors. In particular, HOTAIR upregulation has been associated with tumor aggressiveness, metastasis, and poor survival in gastrointestinal stromal tumor (GIST) patients. We analyzed expression levels of other lncRNAs, H19 and MALAT1, in FFPE tissue specime...
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#1Lorena Incorvaia (University of Palermo)H-Index: 11
#2Daniele Fanale (University of Palermo)H-Index: 16
Last.A. Russo (University of Palermo)H-Index: 10
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#1Lorena Incorvaia (University of Palermo)H-Index: 11
#2Daniele Fanale (University of Palermo)H-Index: 16
Last.Antonio Russo (University of Palermo)H-Index: 71
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Recently, immunotherapy has been shown to be an effective and helpful therapeutic option for the treatment of advanced non-small-cell lung cancer (NSCLC). The activity of antitumor T cells may be restored through the checkpoint blockade using anti-programmed death 1 or anti-programmed death ligand 1 (PD-L1) antibodies, showing, in several cancer patients, an increased progression-free survival and overall survival compared with classical chemotherapy. As recently shown by several studies, the PD...
1 CitationsSource
#1Daniele Fanale (University of Palermo)H-Index: 16
#2Lorena Incorvaia (University of Palermo)H-Index: 11
Last.A. Russo (University of Palermo)H-Index: 10
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#2Lorena Incorvaia (University of Palermo)H-Index: 11
Last.Giuseppe Badalamenti (University of Palermo)H-Index: 19
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#1Antonio Galvano (University of Palermo)H-Index: 10
#2D Scaturro (University of Palermo)H-Index: 1
Last.Antonio Russo (University of Palermo)H-Index: 71
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Abstract Hormonal therapies for receptor positive-breast and prostate cancer patients have shown clinical efficacy but also several side effects including osteoporosis, loss of bone mass and increased fracture risk. Denosumab represents an anti RANKL (receptor activator of nuclear factor-kB ligand) monoclonal anti-body acting as inhibitor of osteoclasts formation, function, and survival, then increasing bone mass. Herein, we performed a systematic review and meta-analysis of randomized controlle...
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#1Daniele SantiniH-Index: 47
#2Antonio Galvano (University of Palermo)H-Index: 10
Last.Viviana Bazan (University of Palermo)H-Index: 27
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Abstract Background Zoledronic Acid is a bisphosphonate used in a 4-week schedule for the treatment of bone metastases. Some randomized trials supported its role also when administered every 12 weeks. Methods we performed a systematic review and a meta-analysis in order to evaluate the two different schedules in terms of skeletal morbidity rate (SMR), skeletal related events (SRE) and adverse events (AEs). Results our results showed a clinical difference favouring the 12-week schedule in terms o...
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#1Giuseppe Badalamenti (University of Palermo)H-Index: 19
#2Lorena Incorvaia (University of Palermo)H-Index: 11
Last.Antonio Russo (University of Palermo)H-Index: 71
view all 9 authors...
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