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Andrew D. Grotzinger
University of Texas at Austin
PsychopathologyPsychologyClinical psychologyHormoneSocial psychology
41Publications
13H-index
385Citations
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Publications 40
Newest
#1K. Paige Harden (University of Texas at Austin)H-Index: 34
#2Laura E. Engelhardt (University of Texas at Austin)H-Index: 13
Last. Elliot M. Tucker-Drob (University of Texas at Austin)H-Index: 34
view all 11 authors...
Objective Symptoms of psychopathology covary across diagnostic boundaries, and a family history of elevated symptoms for a single psychiatric disorder places an individual at heightened risk for a broad range of other psychiatric disorders. Both twin-based and genome-wide molecular methods indicate a strong genetic basis for the familial aggregation of psychiatric disease. This has led researchers to prioritize the search for highly heritable childhood risk factors for transdiagnostic psychopath...
3 CitationsSource
#1Margherita Malanchini (University of Texas at Austin)H-Index: 7
#2Laura E. Engelhardt (University of Texas at Austin)H-Index: 13
Last. K. Paige Harden (University of Texas at Austin)H-Index: 34
view all 11 authors...
The progression of lifelong trajectories of socioeconomic inequalities in health and mortality begins in childhood. Dysregulation in cortisol, a stress hormone that is the primary output of the hypothalamus–pituitary–adrenal (HPA) axis, has been hypothesized to be a mechanism for how early environmental adversity compromises health. However, despite the popularity of cortisol as a biomarker for stress and adversity, little is known about whether cortisol output differs in children being raised i...
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#1Jackson G Thorp (QIMR: QIMR Berghofer Medical Research Institute)H-Index: 2
#2Adrian I. Campos (QIMR: QIMR Berghofer Medical Research Institute)H-Index: 2
Last. Enda M. Byrne (UQ: University of Queensland)H-Index: 35
view all 14 authors...
Depression and anxiety are highly prevalent and comorbid psychiatric traits that cause considerable burden worldwide. Previous studies have revealed substantial genetic overlap between depression, anxiety, and a closely related personality trait, neuroticism. Here, we use factor analysis and genomic structural equation modelling (Genomic SEM) to investigate the genetic factor structure underlying 28 items assessing depression, anxiety and neuroticism. Symptoms of depression and anxiety loaded on...
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#1Phil H. LeeH-Index: 42
#2Verneri AnttilaH-Index: 35
Last. Jordan W. SmollerH-Index: 80
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Summary Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting substantial pleiotropy of contributing loci. However, the nature and mechanisms of these pleiotropic effects remain unclear. We performed analyses of 232,964 cases and 494,162 controls from genome-wide studies of anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, and Tourette syndrome. ...
49 CitationsSource
#1Margherita Malanchini (University of Texas at Austin)H-Index: 7
#2Laura E. Engelhardt (University of Texas at Austin)H-Index: 13
Last. Elliot M. Tucker-Drob (University of Texas at Austin)H-Index: 34
view all 5 authors...
Self-regulation describes the ability to control both behaviors and internal states against a backdrop of conflicting or distracting situations, drives, or impulses. In the cognitive psychology tradition, individual differences in self-regulation are commonly measured with performance-based tests of executive functioning, whereas in the personality psychology tradition, individual differences in self-regulation are typically assessed with report-based measures of impulse control, sustained motiv...
16 CitationsSource
#1Laurel Raffington (University of Texas at Austin)H-Index: 2
#2Margherita Malanchini (University of Texas at Austin)H-Index: 7
Last. Elliot M. Tucker-Drob (University of Texas at Austin)H-Index: 34
view all 10 authors...
Genetic associations with biopsychosocial phenotypes are often interpreted as evidence that the genome codes for fixed end-states. Instead, a given genotype might regulate a dynamic range of phenotypes in response to environmental change. We collected hair cortisol (n = 1,104), salivary cortisol in reaction to an in-laboratory stressor (n = 537), and diurnal salivary cortisol (n = 488) from twins aged 8-15 years in the Texas Twin Project. Baseline genetic variation in both salivary and hair cort...
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#1Alexis C. Wood (BCM: Baylor College of Medicine)H-Index: 6
#2Uku Vainik (UT: University of Tartu)H-Index: 11
Last. Elliot M. Tucker-Drob (University of Texas at Austin)H-Index: 34
view all 8 authors...
BACKGROUND: Executive functions (EFs) comprise a group of cognitive processes that selectively control and regulate attention. Inverse relations have been reported between EFs and BMI. However, the mechanisms underlying this association are not well understood. OBJECTIVES: We aimed to decompose the inverse relation between EFs and BMI into genetic and environmental components. METHODS: We employed a cross-sectional analysis of data from 869 twins aged 7-15 y from the Texas Twin Project, who comp...
1 CitationsSource
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#1Javier de la Fuente (University of Texas at Austin)
#2Gail Davies (Edin.: University of Edinburgh)H-Index: 64
Last. Ian J. Deary (Edin.: University of Edinburgh)H-Index: 132
view all 5 authors...
It has been known for 115 years that, in humans, diverse cognitive traits are positively intercorrelated; this forms the basis for the general factor of intelligence (g). We directly test for a genetic basis for g using data from seven different cognitive tests (N = 11,263 to N = 331,679) and genome-wide autosomal single nucleotide polymorphisms. A genetic g factor accounts for 58.4% (SE = 4.8%) of the genetic variance in the cognitive traits, with trait-specific genetic factors accounting for t...
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#1Mona Ayoub (UIUC: University of Illinois at Urbana–Champaign)H-Index: 2
#2Daniel A. Briley (UIUC: University of Illinois at Urbana–Champaign)H-Index: 18
Last. Elliot M. Tucker-Drob (University of Texas at Austin)H-Index: 34
view all 8 authors...
Parenting is often conceptualized in terms of its effects on offspring. However, children may also play an active role in influencing the parenting they receive. Simple correlations between parenti...
5 CitationsSource
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