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Andrey O. Bogorodskiy
Moscow Institute of Physics and Technology
5Publications
2H-index
12Citations
Publications 5
Newest
#1A. P. Luginina (MIPT: Moscow Institute of Physics and Technology)
#2Anastasiia Gusach (MIPT: Moscow Institute of Physics and Technology)
Last.Elizaveta Lyapina (MIPT: Moscow Institute of Physics and Technology)H-Index: 1
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The G protein–coupled cysteinyl leukotriene receptor CysLT1R mediates inflammatory processes and plays a major role in numerous disorders, including asthma, allergic rhinitis, cardiovascular disease, and cancer. Selective CysLT1R antagonists are widely prescribed as antiasthmatic drugs; however, these drugs demonstrate low effectiveness in some patients and exhibit a variety of side effects. To gain deeper understanding into the functional mechanisms of CysLTRs, we determined the crystal structu...
#1Ivan Maslov (MIPT: Moscow Institute of Physics and Technology)H-Index: 1
#2Andrey O. Bogorodskiy (MIPT: Moscow Institute of Physics and Technology)H-Index: 2
Last.Valentin I. Gordeliy (MIPT: Moscow Institute of Physics and Technology)H-Index: 21
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Research on halophilic microorganisms is important due to their relation to fundamental questions of survival of living organisms in a hostile environment. Here we introduce a novel method to stain halophiles with MitoTracker fluorescent dyes in their growth medium. The method is based on membrane-potential sensitive dyes, which were originally used to label mitochondria in eukaryotic cells. We demonstrate that these fluorescent dyes provide high staining efficiency and are beneficial for multi-...
#1M. A. Shevchenko (RAS: Russian Academy of Sciences)H-Index: 3
#2Andrey O. Bogorodskiy (MIPT: Moscow Institute of Physics and Technology)H-Index: 2
Last.Valentin Borshchevskiy (MIPT: Moscow Institute of Physics and Technology)H-Index: 11
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Susceptibility to fungal infection is commonly associated with impaired neutrophil responses. To study the mechanisms underlying this association, we investigated neutrophil recruitment to the conducting airway wall after Aspergillus fumigatus conidium inhalation in mouse models of drug-induced immunosuppression and antibody-mediated neutrophil depletion (neutropenia) by performing three-dimensional confocal laser-scanning microscopy of whole-mount primary bronchus specimens. Actin staining enab...
Since the introduction of in meso crystallization of membrane proteins in lipidic cubic phase (LCP) by Landau and Rosenbusch in 1996, numerous studies attempted to elucidate the mechanism of in meso crystal nucleation and growth. Here we present a fluorescence microscopy study of the crystallization process of the light-driven proton pump bacteriorhodopsin. The crystallization starts with formation of microcrystals, followed by growth of a dominating crystal at the expense of smaller ones and fo...
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