Thilo Witsch
University of Freiburg
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Publications 18
#2Marcus HortmannH-Index: 4
Last. Ingo AhrensH-Index: 21
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#1Maximilian Mauler (University of Freiburg)H-Index: 9
#2Nadine Herr (University of Freiburg)H-Index: 6
Last. Daniel Duerschmied (University of Freiburg)H-Index: 22
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Background: Platelets store large amounts of serotonin that they release during thrombus formation or acute inflammation. This facilitates hemostasis and modulates the inflammatory response. Method...
9 CitationsSource
#1Thilo Witsch (Harvard University)H-Index: 7
#2Kimberly Martinod (Katholieke Universiteit Leuven)H-Index: 21
Last. Denisa D. Wagner (Harvard University)H-Index: 103
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BackgroundA disintegrin‐like metalloproteinase with thrombospondin motif type 1 member 13 (ADAMTS13), the von Willebrand factor–cleaving enzyme, decreases leukocyte and platelet recruitment and, th...
4 CitationsSource
#1Hideki HayashiH-Index: 20
#2Deya CherpokovaH-Index: 9
Last. Denisa D. WagnerH-Index: 103
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5 CitationsSource
#1Maximilian MaulerH-Index: 9
#2Nadine HerrH-Index: 6
Last. Daniel DuerschmiedH-Index: 22
view all 15 authors...
#1Kimberly Martinod (Harvard University)H-Index: 21
#2Thilo Witsch (Harvard University)H-Index: 7
Last. Denisa D. Wagner (Harvard University)H-Index: 103
view all 10 authors...
Aging promotes inflammation, a process contributing to fibrosis and decline in organ function. The release of neutrophil extracellular traps (NETs [NETosis]), orchestrated by peptidylarginine deiminase 4 (PAD4), damages organs in acute inflammatory models. We determined that NETosis is more prevalent in aged mice and investigated the role of PAD4/NETs in age-related organ fibrosis. Reduction in fibrosis was seen in the hearts and lungs of aged PAD4−/− mice compared with wild-type (WT) mice. An i...
47 CitationsSource
#1Kimberly Martinod (Harvard University)H-Index: 21
#2Thilo Witsch (Harvard University)H-Index: 7
Last. Denisa D. Wagner (Harvard University)H-Index: 103
view all 6 authors...
59 CitationsSource
#1Maximilian MaulerH-Index: 9
#2Thilo WitschH-Index: 7
Last. Daniel DuerschmiedH-Index: 22
view all 9 authors...
Background: Myocardial reperfusion injury leads to platelet neutrophil complex (PNCs) migration into cardiac tissue, which promotes post-infarction necrosis. Local serotonin levels are elevated dur...
#1Nadine HerrH-Index: 6
#2Maximilian MaulerH-Index: 9
Last. Daniel DuerschmiedH-Index: 22
view all 8 authors...
The following funder is missing from the Funding section: Deutsche Herzstiftung. The correct funding information is as follows: This work was funded by the Deutsche Forschungsgemeinschaft (DFG) and the Deutsche Herzstiftung. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
#1Thilo Witsch (University of Freiburg)H-Index: 7
#2Anna Stephan (University of Freiburg)H-Index: 1
Last. Jens Witsch (Columbia University)H-Index: 6
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Abstract Background Patients with medical conditions may present with psychiatric symptoms, which may lead to worse physical health care. Here we present the case of a patient with acute aortic dissection masked by psychiatric symptoms after a stressful event. Case Report A 29-year-old female medical student presented to the Emergency Department (ED) complaining about the feeling of “hysteria” after an argument with her boyfriend earlier the same day. She did not report other symptoms or pain. C...
2 CitationsSource