Anthony Macherone
Agilent Technologies
Publications 6
#1Weier Hao (Duquesne University)
#2H. SkipKingston (Duquesne University)H-Index: 16
Last.Matt PamukuH-Index: 7
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Abstract Stir-bar sorptive extraction has been proven an effective and green extraction method for persistent organic pollutants (POPs) in aqueous samples such as drinking water, wastewater and human serum. In this study, a method was developed to quantify POPs in human whole blood samples using stir bar sorptive extraction-thermal desorption-GC/MS/MS-isotope dilution mass spectrometry (IDMS). This method enables accurate, precise, and sensitive quantification of POPs in human whole blood sample...
#1Robert L. BroadrupH-Index: 1
#2Christopher MayackH-Index: 8
Last.Anthony MacheroneH-Index: 2
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Honey bee (Apis mellifera) health has been severely impacted by multiple environmental stressors including parasitic infection, pesticide exposure, and poor nutrition. The decline in bee health is therefore a complex multifactorial problem which requires a holistic investigative approach. Within the exposome paradigm, the combined exposure to the environment, drugs, food, and individuals' internal biochemistry affects health in positive and negative ways. In the context of the exposome, honey be...
1 CitationsSource
#1Sarah I. Daniels (University of California, Berkeley)H-Index: 3
#2John C. ChambersH-Index: 93
Last.Jaspal S. KoonerH-Index: 84
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2 CitationsSource
#1Helen K. WhiteH-Index: 13
#2Robert L. BroadrupH-Index: 1
Last.Anthony MacheroneH-Index: 2
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#1Robert L. Broadrup (Haverford College)H-Index: 1
#2Christopher Mayack (Swarthmore College)H-Index: 8
Last.Anthony Macherone (Agilent Technologies)H-Index: 2
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A pilot study was conducted to determine if exposome profiles of honey bees ( Apis mellifera ) are associated with Nosema ceranae infection and whether xenobiotic exposures effect changes in known biological pathways of bees. Thirty stationary hives were selected from seven apiaries representing urban and suburban geographies. Foraging bees were harvested during the summer of 2015 and analyzed for Nosema ceranae infection via semi-quantitative polymerase chain reaction (sq-PCR) and discovery-bas...
#1Francesca M. Notarangelo (UMB: University of Maryland, Baltimore)H-Index: 12
#2Hui-Qiu Wu (UMB: University of Maryland, Baltimore)H-Index: 31
Last.Robert Schwarcz (UMB: University of Maryland, Baltimore)H-Index: 79
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We describe here a gas chromatography–tandem mass spectrometry (GC/MS/MS) method for the sensitive and concurrent determination of extracellular tryptophan and the kynurenine pathway metabolites kynurenine, 3-hydroxykynurenine (3-HK), and quinolinic acid (QUIN) in rat brain. This metabolic cascade is increasingly linked to the pathophysiology of several neurological and psychiatric diseases. Methodological refinements, including optimization of MS conditions and the addition of deuterated standa...
31 CitationsSource