José Luis Capelo
Universidade Nova de Lisboa
206Publications
29H-index
2,979Citations
Publications 206
Newest
Published on Feb 1, 2019in Dyes and Pigments 3.77
Gonçalo Marcelo2
Estimated H-index: 2
(Universidade Nova de Lisboa),
Sónia M. G. Pires8
Estimated H-index: 8
(University of Aveiro)
+ 7 AuthorsElisabete Oliveira19
Estimated H-index: 19
(Universidade Nova de Lisboa)
Abstract Multifunctional luminescent nanomaterials based on mesoporous silica SBA-16 doped with a ring-opening rhodamine derivative ( RhNHS ) or with a cationic porphyrin bearing imidazolium substituents ( Porph ) were successfully obtained and characterized. The non-immobilized Porph leads to a selective colorimetric detection for Cu 2+ , Pb 2+ and Hg 2+ in HEPES buffer at pH 7, producing colour changes from violet to pink, green and brown, detecting the minimal amount of 3.6, 5.8 and 3.8 ppm b...
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Published on Feb 1, 2019in Dyes and Pigments 3.77
Elisabete Oliveira19
Estimated H-index: 19
(Universidade Nova de Lisboa),
Hugo M. Santos17
Estimated H-index: 17
(Universidade Nova de Lisboa)
+ 6 AuthorsCarlos Lodeiro32
Estimated H-index: 32
(Universidade Nova de Lisboa)
Abstract The synthesis and full characterization of a family of sustainable luminescent nanoparticles, CdTeQDs@MNs, made of quantum dots coated by modified mesoporous silica nanoparticles is reported. The presence of the luminescent QDs allows the imaging of the nanoparticles during cell internalization, as well as the visualization of selective release of doxorubicin inside the cell (via pH stimuli). The modified mesoporous silica nanoparticles lead to pore size improvement allowing better enca...
2 Citations Source Cite
Published on Jan 1, 2019in Environmental Science and Pollution Research 2.80
Carlos Lodeiro32
Estimated H-index: 32
,
José Luis Capelo29
Estimated H-index: 29
+ 1 AuthorsJavier Lodeiro
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Published on Jan 1, 2019in Journal of Proteomics 3.72
José Luis Capelo29
Estimated H-index: 29
(Universidade Nova de Lisboa),
Carlos Lodeiro32
Estimated H-index: 32
(Universidade Nova de Lisboa)
+ 1 AuthorsGilberto Igrejas22
Estimated H-index: 22
(University of Lisbon)
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Published on May 1, 2018in Talanta 4.24
João Prates , Gonçalo Martins + 3 AuthorsHugo M. Santos17
Estimated H-index: 17
Abstract In this work we present acetonitrile as a tool to modulate the dynamic range of the proteome of complex samples. Different concentrations of acetonitrile ranging from 15% v/v to 65% v/v were used to modulate the protein content of serum samples from healthy people and patients with lymphoma and myeloma. We show that the proteome above 70 kDa is pelleted as a function of the concentration of acetonitrile and that profiling with PCA or Clustering is only possible using the supernatants ob...
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Published on Aug 6, 2018in Materials 2.47
Jamila Djafari2
Estimated H-index: 2
,
Marie T. McConnell + 5 AuthorsJavier Fernández-Lodeiro10
Estimated H-index: 10
The lectin found in the tubers of the Winter Aconite (Eranthis hyemalis) plant (EHL) is a Type II Ribosome Inactivating Protein (RIP). Type II RIPs have shown anti-cancer properties and have great potential as therapeutic agents. Similarly, colloidal gold nanoparticles are successfully used in biomedical applications as they can be functionalised with ligands with high affinity and specificity for target cells to create therapeutic and imaging agents. Here we present the synthesis and characteri...
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Published on Jul 28, 2018in Materials 2.47
Gonçalo Marcelo2
Estimated H-index: 2
,
Jessica Ariana-Machado1
Estimated H-index: 1
+ 5 AuthorsElisabete Oliveira19
Estimated H-index: 19
Luminescent mesoporous silica nanoparticles, CdTeQDs@MNs@PEG1, SiQDs@Isoc@MNs and SiQDs@Isoc@MNs@PEG2, were successfully synthetized and characterized by SEM, TEM, XRD, N2 nitrogen isotherms, 1H NMR, IR, absorption, and emission spectroscopy. Cytotoxic evaluation of these nanoparticles was performed in relevant in vitro cell models, such as human hepatoma HepG2, human brain endothelial (hCMEC/D3), and human epithelial colorectal adenocarcinoma (Caco-2) cell lines. None of the tested nanoparticle...
3 Citations Source Cite
Published on Feb 1, 2018in Talanta 4.24
Susana Jorge3
Estimated H-index: 3
,
J.E. Araújo7
Estimated H-index: 7
+ 4 AuthorsJosé Luis Capelo29
Estimated H-index: 29
Abstract We report on the new microplate horn ultrasonic device as a powerful tool to speed proteomics workflows with unparalleled throughput. 96 complex proteomes were digested at the same time in 4 min. Variables such as ultrasonication time, ultrasonication amplitude, and protein to enzyme ratio were optimized. The "classic" method relying on overnight protein digestion (12 h) and the sonoreactor-based method were also employed for comparative purposes. We found the protein digestion efficien...
2 Citations Source Cite
Published on Feb 1, 2018in Ultrasonics 2.38
Eduardo Araujo , Hugo M. Santos17
Estimated H-index: 17
+ 1 AuthorsJosé Luis Capelo29
Estimated H-index: 29
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