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Wenshu Luo
Centers for Disease Control and Prevention
EndocrinologyWaistAbdominal obesityPopulationMedicine
9Publications
6H-index
70Citations
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Publications 9
Newest
#1Wenshu LuoH-Index: 6
#2Fengmei ChenH-Index: 3
view all 4 authors...
OBJECTIVE: We aimed to detect the synergistic effect between alcohol drinking, smoking and obesity on incident cardiovascular disease (CVD) in a Chinese population- based cohort. METHODS: We performed this study based on a prospective cohort based on a Chinese population in Jiangsu, China. Logistic regression was employed to detect the interaction of smoking, drinking with obesity on susceptibility to CVD, and calculate the odds ratio (OR) of CVD and corresponding 95% confidence interval (CI). R...
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#1Wenshu Luo (CDC: Centers for Disease Control and Prevention)H-Index: 6
#2Fengmei ChenH-Index: 3
Last. Xingjuan Yao (CDC: Centers for Disease Control and Prevention)H-Index: 5
view all 6 authors...
AbstractBackground: Peroxisome proliferator-activated receptor (PPAR) gene plays an important role in obesity and PPAR δ protein is a potent inhibitor; however, few previous studies have focused on this gene.Aim: To investigate the association of haplotypes of PPAR δ gene rs2016520 and rs9794 with abnormal weight (BMI ≥ 24 kg/m2) and abdominal obesity (WC ≥ 90 cm for males and ≥ 80 cm for females) in a Chinese Han population.Subjects and methods: In total, 820 subjects (270 men, 550 women) were ...
3 CitationsSource
#1Wenshu Luo (Soochow University (Suzhou))H-Index: 6
#2Zhirong Guo (Soochow University (Suzhou))H-Index: 10
Last. Xingjuan Yao (CDC: Centers for Disease Control and Prevention)H-Index: 5
view all 6 authors...
Abstract The aim of this study was to examine the independent and combined effects of current smoking and obesity on risk of type 2 diabetes (T2DM) in a Chinese cohort. We analyzed the data from a population-based prospective cohort of 3598 participants aged 35–74 years from Jiangsu, China. A Cox proportional hazards regression model was used to calculate the hazard ratio (HR) of T2DM and corresponding 95% confidence interval (CI), and to examine the interaction between current smoking and obesi...
7 CitationsSource
#1Wenshu LuoH-Index: 6
#2Zhirong GuoH-Index: 1
Last. Xingjuan YaoH-Index: 5
view all 6 authors...
5 CitationsSource
#1Wenshu Luo (CDC: Centers for Disease Control and Prevention)H-Index: 6
#2Fengmei ChenH-Index: 3
Last. Xingjuan Yao (CDC: Centers for Disease Control and Prevention)H-Index: 5
view all 7 authors...
Background: Currently, obesity has become a worldwide health problem and yet little is known about the impact of changes in obesity indicator on incident hypertension. The aim of this study was to compare the impact of changes in the WC and BMI on incident hypertension in a cohort population. Methods: After a baseline investigation, we conducted the first and the second follow-up assessments for subjects after 2 and 5 years, respectively. The associations between the changes in the WC and BMI (m...
6 Citations
#1Wenshu Luo (Soochow University (Suzhou))H-Index: 6
#2Zhirong Guo (Soochow University (Suzhou))H-Index: 10
Last. Jingchao Liu (Soochow University (Suzhou))H-Index: 3
view all 7 authors...
Abstract The high prevalence of alcohol consumption and abdominal obesity and increased incidence of essential hypertension (EH) in China indicates that there may be an interaction between alcohol consumption and abdominal obesity on EH risk. Therefore, we aimed to examine the independent and combined effects of alcohol consumption and abdominal obesity on risk of EH in a Chinese cohort. We analyzed data from a population-based prospective cohort of 2778 participants aged 35–74 years from Jiangs...
14 CitationsSource
#1Wenshu Luo (Soochow University (Suzhou))H-Index: 6
#2Zhirong Guo (Soochow University (Suzhou))H-Index: 10
Last. Jingchao Liu (Soochow University (Suzhou))H-Index: 3
view all 7 authors...
Abstract Background Few prospective studies on association between waist circumference and hypertension have taken account of the dynamic change of WC, which caused by lifestyle modification. Methods After a baseline investigation, we conducted the first and the second follow-up assessments for subjects after 2 and 5years, respectively. The difference value (D-value, the value at the first follow-up minus the value at baseline) in WC was calculated to evaluate 2years change of WC. The associatio...
9 CitationsSource
#1Wenshu Luo (Soochow University (Taiwan))H-Index: 6
#2Zhirong Guo (Soochow University (Taiwan))H-Index: 4
Last. Jingchao Liu (Soochow University (Taiwan))H-Index: 2
view all 10 authors...
Background We investigated the association of 10 single-nucleotide polymorphisms (SNPs) in the peroxisome proliferator-activated receptors (PPARs) with obesity and the additional role of gene–gene interaction.
18 CitationsSource
#1Yi Ding (Soochow University (Suzhou))H-Index: 2
#2Zhi-Rong Guo (Soochow University (Suzhou))H-Index: 1
Last. Wenshu Luo (CDC: Centers for Disease Control and Prevention)H-Index: 6
view all 6 authors...
The peroxisome proliferator-activated receptors (PPARs) -α, -δ/β and -γ are the ligand-activated transcription factors that function as the master regulators of glucose, fatty acid and lipoprotein metabolism, energy balance, cell proliferation and differentiation, inflammation, and atherosclerosis. The objective of the current study was to examine the main and interactive effect of seven single nucleotide polymorphisms (SNPs) of PPARδ/γ in contribution to abdominal obesity. A total of 820 subjec...
8 CitationsSource
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