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Hongwen He
Sun Yat-sen University
30Publications
10H-index
269Citations
Publications 30
Newest
#1Qianyi Deng (SYSU: Sun Yat-sen University)H-Index: 1
#2Qin Liu (SYSU: Sun Yat-sen University)H-Index: 2
Last.Fang Huang (SYSU: Sun Yat-sen University)H-Index: 9
view all 8 authors...
Abstract Background/purpose Melatonin, at physiological concentrations, was previously found to inhibit proliferation and promote odontogenic differentiation in human dental pulp cells (hDPCs), but its effect on apoptosis is unclear. Our study aimed to investigate the effect of melatonin on the H 2 O 2 -mediated viability reduction and apoptosis in hDPCs. Materials and methods hDPCs were treated with H 2 O 2 (0, 250, 500, 1000 μmol/L), melatonin (0, 10 −12 , 10 −10 , 10 −8 mol/L), and melatonin ...
#1Yifan He (SYSU: Sun Yat-sen University)H-Index: 2
#2Wenguo Fan (SYSU: Sun Yat-sen University)H-Index: 9
Last.Fang Huang (SYSU: Sun Yat-sen University)H-Index: 9
view all 6 authors...
#1Wenguo Fan (SYSU: Sun Yat-sen University)H-Index: 9
#2Xiao ZhuH-Index: 2
Last.Hongwen He (SYSU: Sun Yat-sen University)H-Index: 10
view all 7 authors...
#1Huini Zhang (SYSU: Sun Yat-sen University)
#2Qianyi Deng (SYSU: Sun Yat-sen University)H-Index: 1
Last.Fang Huang (SYSU: Sun Yat-sen University)H-Index: 9
view all 8 authors...
#1Jun Kang (SYSU: Sun Yat-sen University)
#2Wenguo Fan (SYSU: Sun Yat-sen University)H-Index: 9
Last.Fang Huang (SYSU: Sun Yat-sen University)H-Index: 9
view all 5 authors...
Stem cells are biological cells that can self-renew and can differentiate into multiple cell lineages. Stem cell-based therapy is emerging as a promising alternative therapeutic option for various disorders. Mesenchymal stem cells (MSCs) are multipotent adult stem cells that are isolated from various tissues and can be used as an alternative to embryonic stem cells. Stem cells from the apical papilla (SCAPs) are a novel population of MSCs residing in the apical papilla of immature permanent teet...
#1Haichao Liu (SYSU: Sun Yat-sen University)H-Index: 1
#2Lei ZhaoH-Index: 1
Last.Wenguo Fan (SYSU: Sun Yat-sen University)H-Index: 9
view all 10 authors...
Satellite glial cells (SGCs), a peripheral neuroglial cell, surround neurons and form a complete envelope around individual sensory neurons in the trigeminal ganglia (TG), which may be involved in modulating neurons in inflammation. The purpose of this study was to determine the effect of dental injury and inflammation on SGCs in the TG. Pulp exposure (PX) was performed on the first maxillary molar of 28 rats. The neurons innervating injured tooth in TG were labeled by the retrograde transport o...
#1Wenguo Fan (SYSU: Sun Yat-sen University)H-Index: 9
#2Yifan HeH-Index: 2
Last.Hongwen HeH-Index: 10
view all 8 authors...
Abstract Melatonin is a hormone mainly synthesized by the pineal gland in vertebrates and known well as an endogenous regulator of circadian and seasonal rhythms. It has been demonstrated that melatonin is involved in many physiological and pathophysiological processes showing antioxidant, anti-apoptotic and anti-inflammatory properties. Nitric oxide (NO) is a free radical gas in the biological system, which is produced by nitric oxide synthase (NOS) family. NO acts as a biological mediator and ...
#1Fuping Zhang (SYSU: Sun Yat-sen University)H-Index: 1
#2Liulin Jiang (SYSU: Sun Yat-sen University)H-Index: 1
Last.Hongwen He (SYSU: Sun Yat-sen University)H-Index: 10
view all 8 authors...
Dental papilla cells (DPCs) belong to precursor cells differentiating to odontoblasts and play an important role in dentin formation and reproduction. This study aimed to explore the changes and and involvement of mitochondrial respiratory function during odontogenic differentiation. Primary DPCs were obtained from first molar dental papilla of neonatal rats and cultured in odontogenic medium for 7, 14, 21 days. DPCs, which expressed mesenchymal surface markers CD29, CD44 and CD90, had the capac...
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