Christopher M. Jones
Liverpool School of Tropical Medicine
Anopheles gambiaeMalariaAnophelesGeneticsBiology
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Publications 34
#1Alastair G. T. Somerville (LSTM: Liverpool School of Tropical Medicine)H-Index: 1
#2Katherine Gleave (LSTM: Liverpool School of Tropical Medicine)H-Index: 6
Last. Lisa J. Reimer (LSTM: Liverpool School of Tropical Medicine)H-Index: 20
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Evidence from experimental infection studies has shown that infected mosquitoes exhibit altered host-seeking behaviours, with suppression and activation of behaviours dependent on the parasite’s development stage. The mechanisms are poorly characterised; however, infections can impact mosquito energy reserves, thereby influencing key life-history traits and behaviours. In addition, filarial infection is likely detrimental to flight due to damage caused by developing worms. This study aimed to ev...
1 CitationsSource
#1Christopher M. Jones (LSTM: Liverpool School of Tropical Medicine)H-Index: 22
#2Hazel Ruth Parry (CSIRO: Commonwealth Scientific and Industrial Research Organisation)H-Index: 18
Last. Jason W. Chapman (University of Exeter)H-Index: 32
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The recent introduction and spread of Helicoverpa armigera throughout South America highlight the invasiveness and adaptability of moths in the Helicoverpa genus. Long-range movement in three key members, H. armigera, H. zea, and H. punctigera, occurs by migration and international trade. These movements facilitate high population admixture and genetic diversity, with important economic, biosecurity, and control implications in today's agricultural landscape. This is particularly true for the sp...
5 CitationsSource
#1Melissa Minter (Ebor: University of York)H-Index: 1
#2Aislinn J. Pearson (Rothamsted Research)H-Index: 3
Last. Christopher M. Jones (LSTM: Liverpool School of Tropical Medicine)H-Index: 22
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1. Every year billions of insects engage in long-distance, seasonal mass migrations which have major consequences for agriculture, ecosystem services and insect-vectored diseases. Tracking this movement in the field is difficult, with mass migrations often occurring at high altitudes and over large spatial scales. 2. As such, tethered flight provides a valuable tool for studying the flight behaviour of insects, giving insights into flight propensity (e.g. distance, duration and velocity) and ori...
9 CitationsSource
Arthropod pests are a profound threat to agricultural production and the health of humans and domestic animals. Worldwide, herbivorous insects and mites cause an estimated 18–20% of crop yield loss per annum representing a value of more than US$470 billion [1]. In turn arthropod-vectored diseases account for more than 17% of all infectious diseases, causing more than 700 000 deaths annually [2]. The control of these damaging pests has for many years relied heavily on the use of synthetic pestici...
3 CitationsSource
#1Christopher M. Jones (LSTM: Liverpool School of Tropical Medicine)H-Index: 22
#2Ka S. Lim (Rothamsted Research)H-Index: 17
Last. Chris Bass (University of Exeter)H-Index: 42
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The genes and genomes of insect pests are shaped by the wide array of selective forces encountered in their environments. While the molecular adaptations that evolve are beginning to be understood at the genomic and transcriptomic level, they have been less well characterized at an epigenetic level. Here, we present a genome-wide map of DNA methylation at single-nucleotide resolution for the cotton bollworm moth, Helicoverpa armigera , a globally invasive pest of agriculture. We show that methyl...
5 CitationsSource
With more than 1 million insect species described to date, it is perhaps unsurprising that at least some have come into conflict with humans. A variety of methods have been developed to control pest insects, but the application of synthetic insecticides remains one of the most widely used and effective approaches. Unfortunately, the inevitable result of the overuse of insecticides for the control of many pest species has been the evolution of resistance (1, 2). The evolutionary consequences of i...
5 CitationsSource
#1Khamis A HajiH-Index: 5
#2Narjis G. Thawer (RTI International)H-Index: 4
Last. Jeremiah Ngondi (RTI International)H-Index: 24
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Background Indoor residual spraying (IRS) of households with insecticide is a principal malaria vector control intervention in Zanzibar. In 2006, IRS using the pyrethroid lambda-cyhalothrine was introduced in Zanzibar. Following detection of pyrethroid resistance in 2010, an insecticide resistance management plan was proposed, and IRS using bendiocarb was started in 2011. In 2014, bendiocarb was replaced by pirimiphos methyl. This study investigated the residual efficacy of pirimiphos methyl (Ac...
11 CitationsSource
#1Christopher M. Jones (Rothamsted Research)H-Index: 22
#2Alexie Papanicolaou (University of Western Sydney)H-Index: 23
Last. Jason W. Chapman (University of Exeter)H-Index: 32
view all 9 authors...
Migration is a key life history strategy for many animals and requires a suite of behavioural, morphological and physiological adaptations which together form the ‘migratory syndrome’. Genetic variation has been demonstrated for many traits that make up this syndrome, but the underlying genes involved remain elusive. Recent studies investigating migration-associated genes have focussed on sampling migratory and nonmigratory populations from different geographic locations but have seldom explored...
23 CitationsSource
#1Kobié H. Toé (LSTM: Liverpool School of Tropical Medicine)H-Index: 3
#2Sagnon N’FaleH-Index: 5
Last. Christopher M. Jones (LSTM: Liverpool School of Tropical Medicine)H-Index: 22
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Background: Since 2011, the level of pyrethroid resistance in the major malaria mosquito, Anopheles coluzzi, has increased to such an extent in Burkina Faso that none of the long lasting insecticide treated nets (LLINs) currently in use throughout the country kill the local mosquito vectors. We investigated whether this observed increase was associated with transcriptional changes in field-caught Anopheles coluzzi using two independent whole-genome microarray studies, performed in 2011 and 2012....
40 CitationsSource
#1Victoria A. Ingham (Warw.: University of Warwick)H-Index: 5
#2Christopher M. Jones (LSTM: Liverpool School of Tropical Medicine)H-Index: 22
Last. Hilary Ranson (LSTM: Liverpool School of Tropical Medicine)H-Index: 69
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Background: The elevated expression of enzymes with insecticide metabolism activity can lead to high levels of insecticide resistance in the malaria vector, Anopheles gambiae. In this study, adult female mosquitoes from an insecticide susceptible and resistant strain were dissected into four different body parts. RNA from each of these samples was used in microarray analysis to determine the enrichment patterns of the key detoxification gene families within the mosquito and to identify additiona...
24 CitationsSource