Veer Gupta
Deakin University
PsychologyDiseaseBiomarker (medicine)BiologyAmyloid
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Publications 93
#1Mehdi Mirzaei (Macquarie University)H-Index: 17
#2Vivek Gupta (Macquarie University)H-Index: 17
Last. Matthew J. McKay (Macquarie University)H-Index: 14
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Current evidence suggests that exposure to chronically induced intraocular pressure (IOP) leads to neurodegenerative changes in the inner retina. This study aimed to determine retinal proteomic alterations in a rat model of glaucoma and compared findings with human retinal proteomics changes in glaucoma reported previously. We developed an experimental glaucoma rat model by subjecting the rats to increased IOP (9.3 vs 20.8 mm Hg) by weekly microbead injections into the eye (8 weeks). The retinal...
#2Mehdi MirzaeiH-Index: 17
Last. Veer GuptaH-Index: 17
view all 11 authors...
#1Kunal DhimanH-Index: 1
#2Veer GuptaH-Index: 17
Last. Ashley I. Bush (Centre for Mental Health)H-Index: 131
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#1Mehdi MirzaeiH-Index: 17
#2Vivek K. GuptaH-Index: 31
Last. Stuart L. GrahamH-Index: 40
view all 5 authors...
#1Dhamidhu Eratne (University of Melbourne)H-Index: 2
#2Samantha M. Loi (University of Melbourne)H-Index: 7
Last. Dennis Velakoulis (University of Melbourne)H-Index: 59
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Objective:Neurofilament light has shown promise as a biomarker for diagnosis, staging and prognosis in a wide range of neurological and neurodegenerative disorders. This study explored the utility ...
#1Vivek Gupta (Macquarie University)H-Index: 17
#1Vivek K. GuptaH-Index: 31
Last. Stuart L. GrahamH-Index: 40
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#1W.M.A.D. Binosha Fernando (ECU: Edith Cowan University)H-Index: 2
#2Veer Gupta (Deakin University)H-Index: 17
Last. Ralph N. MartinsH-Index: 75
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#1Kunal Dhiman (ECU: Edith Cowan University)H-Index: 1
#2Kaj Blennow (University of Gothenburg)H-Index: 123
Last. Veer Gupta (ECU: Edith Cowan University)H-Index: 17
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Alzheimer’s disease (AD) is a multifactorial age-related brain disease. Numerous pathological events run forth in the brain leading to AD. There is an initial long, dormant phase before the clinical symptoms become evident. There is a need to diagnose the disease at the preclinical stage since therapeutic interventions are most likely to be effective if initiated early. Undoubtedly, the core cerebrospinal fluid (CSF) biomarkers have a good diagnostic accuracy and have been used in clinical trial...
2 CitationsSource
#1Yogita Dheer (Macquarie University)H-Index: 6
#2Nitin Chitranshi (Macquarie University)H-Index: 8
Last. Vivek K. Gupta (Macquarie University)H-Index: 31
view all 10 authors...
Abstract Retinoid X receptors (RXRs) play an important role in transcription, are involved in numerous cellular networks from cell proliferation to lipid metabolism and are essential for normal eye development. RXRs form homo or heterodimers with other nuclear receptors, bind to DNA response elements and regulate several biological processes including neurogenesis. Mounting evidence suggests that RXR activation by selective RXR modulators (sRXRms) may be neuroprotective in the central nervous sy...
1 CitationsSource