Rory Collins
Clinical Trial Service Unit
Publications 557
#1Louisa Gnatiuc (University of Oxford)H-Index: 11
#2J Alegre-Diaz (UNAM: National Autonomous University of Mexico)H-Index: 6
Last.Robert Clarke (University of Oxford)H-Index: 14
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#1Yuanjie PangH-Index: 3
Last.Robert ClarkeH-Index: 14
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Background - Physical inactivity and sedentary behaviour are associated with higher risks of cardiovascular disease (CVD). Little is known about the relevance of circulating metabolites for these a...
#1Alexander J. Mentzer (University of Oxford)H-Index: 11
#2Nicole Brenner (DKFZ: German Cancer Research Center)H-Index: 3
Last.Gilean McVean (University of Oxford)H-Index: 77
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Background: Certain infectious agents are recognised causes of cancer and potentially other chronic diseases. Identifying associations and understanding pathological mechanisms involving infectious agents and subsequent chronic disease risk will be possible through measuring exposure to multiple infectious agents in large-scale prospective cohorts such as UK Biobank. Methods: Following expert consensus we designed a Multiplex Serology platform capable of simultaneously measuring quantitative ant...
#1M Arnold (Clinical Trial Service Unit)H-Index: 1
#2Andrew Linden (Clinical Trial Service Unit)
Last.Yuexin Chen (Peking Union Medical College Hospital)
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Background Lean body mass has been identified as a key determinant of left ventricular mass and wall thickness. However, the importance of lean body mass or other body‐size measures as normative de...
#1Jemma C. Hopewell (University of Oxford)H-Index: 38
#2Maysson Ibrahim (University of Oxford)
Last.Rory Collins (University of Oxford)H-Index: 131
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#1Iryna Schlackow (University of Oxford)H-Index: 8
#2Seamus Kent (University of Oxford)H-Index: 7
Last.Alastair Gray (University of Oxford)H-Index: 64
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Statin-based treatments reduce cardiovascular disease (CVD) risk in patients with non-dialysis chronic kidney disease (CKD), but it is unclear which regimen is the most cost-effective. We used the Study of Heart and Renal Protection (SHARP) CKD-CVD policy model to evaluate the effect of statins and ezetimibe on quality-adjusted life years (QALYs) and health care costs in the United States (US) and the United Kingdom (UK). Net costs below $100,000/QALY (US) or £20,000/QALY (UK) were considered co...
#1S Parish (Medical Research Council)H-Index: 55
#2M Arnold (Clinical Trial Service Unit)H-Index: 1
Last.Rory Collins (Clinical Trial Service Unit)H-Index: 131
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Importance A better understanding of the role of atherosclerosis in the development of ischemic stroke subtypes could help to improve strategies for prevention of stroke worldwide. Objective To assess the role of carotid atherosclerosis in the association between major cardiovascular risk factors and ischemic stroke subtypes. Design, Setting, and Participants The prospective China Kadoorie Biobank cohort study was conducted in the general population of 5 urban and 5 rural areas in China, with a ...