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Yang Jin
Oslo University Hospital
26Publications
7H-index
185Citations
Publications 26
Newest
#1Mahsa Jalili (NTNU: Norwegian University of Science and Technology)H-Index: 4
#2Yang Jin (NMBU: Norwegian University of Life Sciences)H-Index: 7
Last.Alberto Pallavicini (UniTS: University of Trieste)H-Index: 32
view all 10 authors...
The quality and relative amounts of dietary lipids may affect the health and growth of cultured Atlantic salmon. So far, little is known about their effects on the performance of the fish immune system during early life stages and, in particular their importance in the transition from endogenous nutrition (yolk) in the alevin stage to exogenous nutrition in the later fry stage. We investigated the immunomodulatory effects of fish oil, vegetable oil and phospholipid-rich oil in feeds for farmed A...
#1Xia Sheng (HUST: Huazhong University of Science and Technology)H-Index: 5
#2Xia Sheng (HUST: Huazhong University of Science and Technology)H-Index: 1
Last.Ladan Fazli (Vancouver Prostate Centre)H-Index: 48
view all 16 authors...
Activation of endoplasmic reticulum (ER) stress/the unfolded protein response (UPR) has been linked to cancer, but the molecular mechanisms are poorly understood and there is a paucity of reagents to translate this for cancer therapy. Here, we report that an IRE1α RNase-specific inhibitor, MKC8866, strongly inhibits prostate cancer (PCa) tumor growth as monotherapy in multiple preclinical models in mice and shows synergistic antitumor effects with current PCa drugs. Interestingly, global transcr...
#1Nora Pällmann (University of Oslo)H-Index: 1
#2Marte Livgård (University of Oslo)
Last.Manohar Pradhan (Oslo University Hospital)H-Index: 9
view all 20 authors...
Cancer cells exploit many of the cellular adaptive responses to support their survival needs. One such critical pathway in eukaryotic cells is the unfolded protein response (UPR) that is important in normal physiology as well as disease states, including cancer. Since UPR can serve as a lever between survival and death, regulated control of its activity is critical for tumor formation and growth although the underlying mechanisms are poorly understood. Here we show that one of the main transcrip...
#1Ji-Hua Shi (Zhengzhou University)H-Index: 5
#2Wen-Zhi Guo (Zhengzhou University)H-Index: 5
Last.Shui‐Jun Zhang (Zhengzhou University)H-Index: 1
view all 8 authors...
#1Cheng Xu (KIZ: Kunming Institute of Zoology)
#2Yunfei Wang (KIZ: Kunming Institute of Zoology)H-Index: 1
Last.Ren Lai (KIZ: Kunming Institute of Zoology)H-Index: 34
view all 10 authors...
Pancreatic cancer remains one of the deadliest human cancers despite current advances in conventional therapeutics including surgery and adjuvant therapies. Here, we showed that LZ1, a peptide derived from a snake venom cathelicidin, significantly inhibited growth of pancreatic cancer cells by inducing autophagy-dependent cell death both in vitro and in vivo. The LZ1-induced cell death was blocked by pharmacological or genetic inhibition of autophagy. In orthotopic model of pancreatic cancer, sy...
#1Yang Jin (NTNU: Norwegian University of Science and Technology)H-Index: 7
#2Rolf Erik Olsen (NTNU: Norwegian University of Science and Technology)H-Index: 30
Last.Simen Rød Sandve (NMBU: Norwegian University of Life Sciences)H-Index: 16
view all 11 authors...
Abstract The onset of first feeding is a critical period for Atlantic salmon ( Salmo salar ). The fish goes through a dramatic transition, from using the yolk sac as an energy and nutrient resource to rely on exogenous food. However, the digestive system of salmon is not fully developed at start feeding. This is especially true for digestion and absorption of dietary lipids. To optimize lipid composition of the initial feed for better growth and development of salmon, it is important to have a s...
#1Yang Jin (NTNU: Norwegian University of Science and Technology)H-Index: 7
#2Rolf Erik Olsen (NTNU: Norwegian University of Science and Technology)H-Index: 30
Last.Simen Rød Sandve (NMBU: Norwegian University of Life Sciences)H-Index: 16
view all 11 authors...
It has been suggested that the high phospholipid (PL) requirement in Atlantic salmon (Salmo salar) fry is due to insufficient intestinal de-novo synthesis causing low lipoprotein (LP) production and reduced transport capacity of dietary lipids. However, in-depth ontogenetic analysis of intestinal PL and LP synthesis with the development of salmon has yet to be performed. Therefore, in this paper we used RNA-Seq technology to investigate the expression of genes involved in PL synthesis and LP for...
#1Gareth Benjamin Gillard (NMBU: Norwegian University of Life Sciences)H-Index: 3
#2Thomas Nelson Harvey (NMBU: Norwegian University of Life Sciences)H-Index: 2
Last.Jon Olav Vik (NMBU: Norwegian University of Life Sciences)H-Index: 18
view all 11 authors...
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