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Glen Stecher
Temple University
SoftwareMega-GeneticsBiologyPhylogenetics
8Publications
7H-index
69.1kCitations
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Publications 9
Newest
#1Glen Stecher (TU: Temple University)H-Index: 7
#2Koichiro Tamura (Tokyo Metropolitan University)H-Index: 29
Last. Sudhir Kumar (TU: Temple University)H-Index: 65
view all 3 authors...
The Molecular Evolutionary Genetics Analysis (MEGA) software enables comparative analysis of molecular sequences in phylogenetics and evolutionary medicine. Here, we introduce the macOS version of the MEGA software. This new version eliminates the need for virtualization and emulation programs previously required to use MEGA on Apple computers. MEGA for macOS utilizes memory and computing resources efficiently for conducting evolutionary analyses on macOS. It has a native Cocoa graphical user in...
15 CitationsSource
#1Sudhir Kumar (TU: Temple University)H-Index: 65
#2Glen Stecher (TU: Temple University)H-Index: 7
Last. Koichiro Tamura (Tokyo Metropolitan University)H-Index: 29
view all 5 authors...
1,067 CitationsSource
#1Sudhir Kumar (TU: Temple University)H-Index: 65
#2Glen Stecher (TU: Temple University)H-Index: 7
Last. S. Blair Hedges (TU: Temple University)H-Index: 56
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Evolutionary information on species divergence times is fundamental to studies of biodiversity, development, and disease. Molecular dating has enhanced our understanding of the temporal patterns of species divergences over the last five decades, and the number of studies is increasing quickly due to an exponential growth in the available collection of molecular sequences from diverse species and large number of genes. Our TimeTree resource is a public knowledge-base with the primary focus to mak...
298 CitationsSource
#1Sudhir Kumar (TU: Temple University)H-Index: 65
#2Glen Stecher (TU: Temple University)H-Index: 7
Last. Koichiro Tamura (Tokyo Metropolitan University)H-Index: 29
view all 3 authors...
Abstract We present the latest version of the Molecular Evolutionary Genetics Analysis (Mega) software, which contains many sophisticated methods and tools for phylogenomics and phylomedicine. In this major upgrade, Mega has been optimized for use on 64-bit computing systems for analyzing larger datasets. Researchers can now explore and analyze tens of thousands of sequences in Mega The new version also provides an advanced wizard for building timetrees and includes a new functionality to automa...
11.7k CitationsSource
#1Glen Stecher (KAU: King Abdulaziz University)H-Index: 7
#2Liu Lu (KAU: King Abdulaziz University)H-Index: 34
Last. Sudhir Kumar (KAU: King Abdulaziz University)H-Index: 65
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Summary: Computational diagnosis of amino acid variants in the human exome is the first step in assessing the disruptive impacts of non-synonymous single nucleotide variants (nsSNVs) on human health and disease. The Molecular Evolutionary Genetics Analysis software with mutational diagnosis (MEGA-MD) is a suite of tools developed to forecast the deleteriousness of nsSNVs using multiple methods and to explore nsSNVs in the context of the variability permitted in the longterm evolution of the affe...
17 CitationsSource
#1Ashley C. BanyardH-Index: 28
#2P. R. WakeleyH-Index: 20
view all 16 authors...
in Greece. Rabies Bulletin Europe. 2011;35:5–7. 4. Picard-Meyer E, Mrenoshki S, Milicevic V, Ilieva D, Cvetkovikj I, Cvetkovikj A, et al. Molecular characterization of rabies virus strains in the Republic of Macedonia. Arch Virol. 2013;158:237–40. http://dx. doi.org/10.1007/s00705-012-1466-9 5. Tsiodras S, Dougas G, Baka A, Billi-nis C, Doudounakis S, Balaska A, et al Re-emergence of animal rabies in northern Greece and subsequent human exposure—March 2013. Euro Surveill. 2013;18:20474. 6. Hayma...
#1Koichiro Tamura (Tokyo Metropolitan University)H-Index: 29
#2Glen Stecher (ASU: Arizona State University)H-Index: 7
Last. Sudhir Kumar (ASU: Arizona State University)H-Index: 65
view all 5 authors...
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference...
24.3k CitationsSource
#1Koichiro TamuraH-Index: 29
#2Glen StecherH-Index: 7
Last. Saudi ArabiaH-Index: 2
view all 6 authors...
We announce the release of an advanced version of the Molecular Evolutionary Genetics Analysis (MEGA) software, which currently contains facilities for building sequence alignments, inferring phylogenetic histories, and conducting molecular evolutionary analysis. In version 6.0, MEGA now enables the inference of timetrees, as it implements the RelTime method for estimating divergence times for all branching points in a phylogeny. A new Timetree Wizard in MEGA6 facilitates this timetree inference...
14 Citations
#1Koichiro Tamura (ASU: Arizona State University)H-Index: 29
#2Daniel S. Peterson (ASU: Arizona State University)H-Index: 14
Last. Sudhir Kumar (ASU: Arizona State University)H-Index: 65
view all 6 authors...
Comparative analysis of molecular sequence data is essential for reconstructing the evolutionary histories of species and inferring the nature and extent of selective forces shaping the evolution of genes and species. Here, we announce the release of Molecular Evolutionary Genetics Analysis version 5 (MEGA5), which is a user-friendly software for mining online databases, building sequence alignments and phylogenetic trees, and using methods of evolutionary bioinformatics in basic biology, biomed...
31.7k CitationsSource
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