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Claudia K. Fox
University of Minnesota
Body mass indexObesityWeight lossDiabetes mellitusMedicine
36Publications
11H-index
539Citations
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Publications 39
Newest
#1Jaime M. Moore (Anschutz Medical Campus)
#2Matthew Haemer (Anschutz Medical Campus)H-Index: 10
Last. Claudia K. Fox (UMN: University of Minnesota)H-Index: 11
view all 3 authors...
Abstract As metabolic and bariatric surgery (MBS) increasingly becomes a treatment of choice for adolescents with severe obesity, there is a need to understand how to deliver pre- and postoperative care in ways that maximize long-term safety and efficacy. This article describes major pre- and postoperative goals, lifestyle modification targets, and, when necessary, pharmacologic management strategies for adolescents undergoing MBS. Three categories of evidence were used–studies of pre- and posto...
Source
#1Elise F. NorthropH-Index: 1
#2Liming Milbauer (UMN: University of Minnesota)H-Index: 12
Last. Justin R. Ryder (UMN: University of Minnesota)H-Index: 9
view all 9 authors...
Aim: We assessed reproducibility of endothelial microparticles (EMPs) enumeration among youth. Methods & results: Four microparticle (MP) indices - total MP per microliter platelet free plasma (PFP), total EMPs per microliter PFP, percent activated EMPs and percent lactadherin positive (LACT[+]) of total EMPs - were measured at two visits (baseline and 7 +/- 3 days follow-up) to determine reproducibility overall and by obesity status. We examined CD31(+) or CD144(+) with CD41-EMP events of size ...
Source
#1Aaron S. Kelly (UMN: University of Minnesota)H-Index: 28
#2Alexander M. Kaizer (Anschutz Medical Campus)H-Index: 7
Last. Donald R. Dengel (UMN: University of Minnesota)H-Index: 38
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OBJECTIVE: This study aimed to determine whether children and adolescents demonstrate, similarly to adults, a threshold of total percent body fat (%BF) above which the slope of visceral adipose tissue (VAT) rises. METHODS: This cross-sectional study included 557 youth, aged 8 to 18 years, with a wide range of BMI values. Dual-energy x-ray absorptiometry was used to determine body composition (including VAT), and fasting blood was collected for measurement of lipids, glucose, insulin, and biomark...
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#1Eric M. Bomberg (UMN: University of Minnesota)H-Index: 3
#2Justin R. Ryder (UMN: University of Minnesota)H-Index: 9
Last. Aaron S. Kelly (UMN: University of Minnesota)H-Index: 28
view all 10 authors...
It remains largely unknown as to why some individuals experience substantial weight loss with obesity interventions, while others receiving these same interventions do not. Person-specific characte...
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#1Amy C. Gross (UMN: University of Minnesota)H-Index: 12
#2Alexander M. Kaizer (Anschutz Medical Campus)H-Index: 7
Last. Claudia K. Fox (UMN: University of Minnesota)H-Index: 11
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Pediatric obesity is a serious public health concern affecting almost 16% of two- to five-year-olds. Prior research has not sufficiently addressed how various factors combine to contribute to the h...
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#1Claudia K. Fox (UMN: University of Minnesota)H-Index: 11
#2Amy C. Gross (UMN: University of Minnesota)H-Index: 12
Last. Aaron S. Kelly (UMN: University of Minnesota)H-Index: 28
view all 7 authors...
Purpose of Review This review describes (1) the clinical assessment of pediatric patients with severe obesity, including a summary of salient biological, psychological, and social factors that may be contributing to the patient’s obesity and (2) the current state of treatment strategies for pediatric severe obesity, including lifestyle modification therapy, pharmacotherapy, and metabolic and bariatric surgery.
1 CitationsSource
#1Seema Kumar (Mayo Clinic)H-Index: 18
#2Eileen C. King (University of Cincinnati Academic Health Center)H-Index: 2
Last. B. GraceH-Index: 1
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Objective To describe treatment outcomes of children and adolescents enrolled in the Pediatric Obesity Weight Evaluation Registry, a consortium of multicomponent pediatric weight management programs in the US. Study design This multicenter prospective observational cohort study, established in 2013, includes youth (2-18 years of age) with obesity enrolled from 31 Pediatric Obesity Weight Evaluation Registry (POWER) sites over a 2-year period and followed up to 12 months. Weight status was evalua...
3 CitationsSource
#1Amy C. Gross (UMN: University of Minnesota)H-Index: 12
#2Alexander M. Kaizer (Anschutz Medical Campus)H-Index: 7
Last. Claudia K. Fox (UMN: University of Minnesota)H-Index: 11
view all 10 authors...
3 CitationsSource
#1Gitanjali Srivastava (BU: Boston University)H-Index: 4
#2Claudia K. Fox (UMN: University of Minnesota)H-Index: 11
Last. Caroline M. Apovian (BU: Boston University)H-Index: 4
view all 12 authors...
6 CitationsSource
#1Claudia K. Fox (UMN: University of Minnesota)H-Index: 11
#2Aaron S. Kelly (UMN: University of Minnesota)H-Index: 28
There is a gap in treatment modalities for pediatric patients with obesity for whom lifestyle modification therapy, on the one hand, may be insufficient to meaningfully reduce BMI, and bariatric surgery, which on the other hand, may not be indicated, available or desired. Although pharmacotherapy may help fill this treatment void, there is a paucity of FDA-approved medications indicated for pediatric obesity and further, most are single agents with only modest mean treatment effects. In contrast...
1 CitationsSource
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