Céline Langendorf
VirologyPediatricsMalariaSevere Acute MalnutritionMedicine
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Publications 33
#1Naouale Maataoui (French Institute of Health and Medical Research)
#2Céline LangendorfH-Index: 9
Last. Paul-Louis Woerther (Paris 12 Val de Marne University)H-Index: 2
view all 11 authors...
#1Junjie Ding (Fudan University)
Last. Joel Tarning (MU: Mahidol University)H-Index: 29
view all 10 authors...
#2Bachir AssaoH-Index: 1
Last. Rebecca F. GraisH-Index: 30
view all 12 authors...
Rapid diagnostic tests (RDT) for malaria are common, but their performance varies. Tests using histidine-rich protein 2 (HRP2) antigen are most common, and many have high sensitivity. HRP2 tests can remain positive for weeks after treatment, limiting their specificity and usefulness in high-transmission settings. Tests using Plasmodium lactate dehydrogenase (pLDH) have been less widely used but have higher specificity, mostly due to a much shorter time to become negative. A prospective, health c...
#1Patrick KeatingH-Index: 4
Last. Sandra CohuetH-Index: 10
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Measles continues to circulate in the Democratic Republic of Congo, and the country suffered from several important outbreaks over the last 5 years. Despite a large outbreak starting in the former province of Katanga in 2010 and the resulting immunization activities, another outbreak occurred in 2015 in this same region. We conducted measles seroprevalence surveys in four health zones (HZ) in the former Katanga Province in order to assess the immunity against measles in children 6 months to 14 y...
#1Elisa ArdizzoniH-Index: 6
#1Elisa Ardizzoni (Institute of Tropical Medicine Antwerp)
Last. Maryline BonnetH-Index: 22
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Background: Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low resource countries. We aimed to assess the effect of OMNIgene® SPUTUM (OM-S) and ethanol in preserving sputum for Xpert and OM-S for mycobacteria growth indicator tube (MGIT) testing over a period of 15 and 8 days respectively. Methods: Sputum were collected from newly diagnosed smear-positive patients. For Xpert, pooled samples were split into 5 aliq...
Background Healthcare-associated infections pose a major, yet often preventable risk to patient safety. Poor hand hygiene among healthcare personnel and unsanitary hospital environments may contribute to this risk in low-income settings. We aimed to describe hand hygiene behaviour and environmental contamination by season in a rural, sub-Saharan African hospital setting.
#1Rebecca F. GraisH-Index: 30
Last. Carol Hopkins Sibley (UW: University of Washington)H-Index: 30
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In Niger, malaria transmission is markedly seasonal with most of the disease burden occurring in children during the rainy season. Seasonal malaria chemoprevention (SMC) with amodiaquine plus sulfadoxine–pyrimethamine (AQ + SP) is recommended in the country to be administered monthly just before and during the rainy season. Moreover, clinical decisions on use of SP for intermittent preventive treatment in pregnancy (IPTp) now depend upon the validated molecular markers for SP resistance in Plasm...
4 CitationsSource
#1Olivier le Polain de Waroux (Lond: University of London)H-Index: 6
#2Stefan Flasche (Lond: University of London)H-Index: 21
Last. W. John Edmunds (Lond: University of London)H-Index: 42
view all 9 authors...
This dataset contained the data that was used in the analysis of the manuscript entitled "Identifying human encounters that shape the transmission of Streptococcus pneumoniae and other acute respiratory infections". The study was conducted in Sheema North Sub-District (South-West Uganda) between January and March 2014. Sixty clusters were randomly selected from the 215 villages and two small district towns (Kabwohe and Itendero) in the study area, proportionally to the population size of each vi...
8 CitationsSource
#1Elizabeth Kemigisha (Mbarara University of Science and Technology)H-Index: 4
#2Deborah NanjebeH-Index: 3
Last. Juliet Mwanga-Amumpaire (Mbarara University of Science and Technology)H-Index: 10
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Acute central nervous system (CNS) infections in children in sub-Saharan Africa are often fatal. Potential contributors include late presentation, limited diagnostic capacity and inadequate treatment. A more nuanced understanding of treatment practices with a goal of optimizing such practices is critical to prevent avoidable case fatality. We describe empiric antimicrobial treatment, antibiotic resistance and treatment adequacy in a prospective cohort of 459 children aged two months to 12 years ...
1 CitationsSource
#2Bachir AssaoH-Index: 1
Last. Rebecca F. GraisH-Index: 30
view all 13 authors...
Background Antibiotic prophylaxis for contacts of meningitis cases is not recommended during outbreaks in the African meningitis belt. We assessed the effectiveness of single-dose oral ciprofloxacin administered to household contacts and in village-wide distributions on the overall attack rate (AR) in an outbreak of meningococcal meningitis. Methods and findings In this 3-arm, open-label, cluster-randomized trial during a meningococcal meningitis outbreak in Madarounfa District, Niger, villages ...
9 CitationsSource