Match!
Kate L. Erickson
University of California, Los Angeles
14Publications
4H-index
62Citations
Publications 14
Newest
#1Jianxun SongH-Index: 20
#2Adam W. MaillouxH-Index: 7
Last.Zhenzhen LiuH-Index: 7
view all 33 authors...
#1Geoffrey C. Owens (UCLA: University of California, Los Angeles)H-Index: 5
#2Kate L. Erickson (UCLA: University of California, Los Angeles)H-Index: 4
Last.Carol A. Kruse (UCLA: University of California, Los Angeles)H-Index: 24
view all 10 authors...
Background Rasmussen encephalitis (RE) is a rare neuroinflammatory disease characterized by intractable seizures and progressive atrophy on one side of the cerebrum. Perivascular cuffing and clusters of T cells in the affected cortical hemisphere are indicative of an active cellular immune response.
10 CitationsSource
#1Michelle J. Hickey (UCLA: University of California, Los Angeles)H-Index: 9
#2Horacio Soto (UCLA: University of California, Los Angeles)H-Index: 19
Last.Carol A. Kruse (UCLA: University of California, Los Angeles)H-Index: 24
view all 10 authors...
In a Phase 1 dose escalation study we evaluated the safety, feasibility, toxicity, and survival of patients treated with allogeneic cytotoxic T lymphocytes and recombinant IL-2 (alloCTL, rIL-2) infusion administered to the resection cavity of patients with recurrent glioma (WHO grade III or IV). AlloCTL are generated when gamma-irradiated lymphoblasts from the brain tumor patient stimulate the proliferation of peripheral blood mononuclear cells (PBMC) isolated from an HLA-disparate healthy donor...
Source
#1Yuki Kato (UCLA: University of California, Los Angeles)H-Index: 2
#2Michelle J. Hickey (UCLA: University of California, Los Angeles)H-Index: 9
Last.Noriyuki KasaharaH-Index: 38
view all 9 authors...
Source
#1Kate L. Erickson (UCLA: University of California, Los Angeles)H-Index: 4
#2Michelle J. Hickey (UCLA: University of California, Los Angeles)H-Index: 9
Last.Carol A. Kruse (UCLA: University of California, Los Angeles)H-Index: 24
view all 9 authors...
We report a novel adaptation of the Radial Monolayer Cell Migration assay, first reported to measure the radial migration of adherent tumor cells on extracellular matrix proteins, for measuring the motility of fluorescently-labeled, non-adherent human or murine effector immune cells. This technique employs a stainless steel manifold and 10-well Teflon slide to focally deposit non-adherent T cells into wells prepared with either confluent tumor cell monolayers or extracellular matrix proteins. Li...
Source
#1Neil HoaH-Index: 16
#2Lisheng GeH-Index: 9
Last.Martin R. JadusH-Index: 24
view all 9 authors...
Cancer cells derived from Glioblastoma multiforme possess membranous protrusions allowing these cells to infiltrate surrounding tissue, while resisting lymphocyte cytotoxicity. Microvilli and filopodia are supported by actin filaments cross-linked by fascin. Fascin-1 was genetically silenced within human U251 glioma cells; these knock-down glioma cells lost their microvilli/filopodia. The doubling time of these fascin-1 knock-down cells was doubled that of shRNA control U251 cells. Fascin-1 knoc...
7 Citations
#1Neil HoaH-Index: 16
#2Lisheng GeH-Index: 9
view all 9 authors...
Cancer cells derived from Glioblastoma multiforme possess membranous protrusions allowing these cells to infiltrate surrounding tissue, while resisting lymphocyte cytotoxicity. Microvilli and filopodia are supported by actin filaments cross-linked by fascin. Fascin-1 was genetically silenced within human U251 glioma cells; these knock- down glioma cells lost their microvilli/filopodia. The doubling time of these fascin-1 knock-down cells was doubled that of shRNA control U251 cells. Fascin-1 kno...
#1Richard G. EversonH-Index: 11
#2Colin C. MaloneH-Index: 6
Last.Carol A. KruseH-Index: 24
view all 7 authors...
#1Kate L. Erickson (UCLA: University of California, Los Angeles)H-Index: 4
#2Colin C. Malone (UCLA: University of California, Los Angeles)H-Index: 6
Last.Carol A. Kruse (UCLA: University of California, Los Angeles)H-Index: 24
view all 8 authors...
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA The radial monolayer cell migration assay was originally developed to measure the infiltrative properties of adherent tumor cells on individual extracellular matrix (ECM) proteins, or on ECM extracted from tumor cell monolayers. For this assay a single cell suspension of tumor cells is seeded using a cell sedimentation manifold (CSM), precisely into the center of Teflon-masked, ECM-coated slide wells. The adherent tumor cells ...
Source
#1Neil HoaH-Index: 16
#2Lisheng GeH-Index: 9
Last.Martin R. JadusH-Index: 24
view all 13 authors...
Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA Big Potassium (BK) ion channels have several splice variants. One splice variant initially described within human glioma cells is called the glioma BK channel (gBK). This isoform consists of 33 amino acids inserted into the intracellular region of the BK ion channel. Using a gBK-specific antibody, we detected gBK within 3 human small cell lung cancer (SCLC) lines. Patch clamping revealed that functional membrane channels were ...
Source
12