Akiyoshi Takami
Aichi Medical University
Publications 228
#1Masamitsu YanadaH-Index: 24
#2Akiyoshi Takami (Aichi Medical University)H-Index: 26
Last.Shingo Yano (Jikei University School of Medicine)H-Index: 13
view all 17 authors...
Autologous hematopoietic cell transplantation (HCT) has not gained universal popularity in the treatment of acute myeloid leukemia (AML), and its status remains unclear. To determine the implementation status and outcomes of autologous HCT for adults with AML in Japan, we analyzed data from 1,174 patients (including 446 with acute promyelocytic leukemia [APL]) who underwent autologous HCT between 1992 and 2016 consecutively reported to the Japanese nationwide transplantation registry. The annual...
1 CitationsSource
#1Keiko Ogawa-Ochiai (Kanazawa University)H-Index: 5
#2Takamasa Katagiri (Kanazawa University)H-Index: 8
Last.Eriko Morishita (Kanazawa University)H-Index: 19
view all 7 authors...
Abstract Background Physical/mental fatigue can alter behavior and reduce cognitive abilities. Even in healthy people, general fatigue correlates with NK cell function. Juzentaihoto (JTT) is a popular Kampo medicine used to treat general fatigue. In many animal models, JTT enhances immune functions, such as cytotoxic T-lymphocyte and NK cell activities. This is the first clinical study has examined the effect of JTT in patients with general fatigue. Purpose We investigated whether peripheral NK ...
#1Keijiro SatoH-Index: 5
#2Ken Ishiyama (Kanazawa University)H-Index: 15
Last.Shinji Nakao (Kanazawa University)H-Index: 42
view all 12 authors...
A “biosimilar” is a biotechnological product with a lower cost profile and equivalent efficacy and safety to the originator, but post-marketing clinical evaluation of biosimilar products has not been adequately conducted. We prospectively investigated the utility of biosimilar filgrastim in 13 peripheral blood stem cell (PBSC) donors from June 2014 to January 2017. In addition, we retrospectively compared these to another 13 PBSC donors mobilized with the originator filgrastim in the same period...
#1Shohei Mizuno (Aichi Medical University)H-Index: 8
#2Masamitsu YanadaH-Index: 24
Last.Akiyoshi Takami (Aichi Medical University)H-Index: 26
view all 17 authors...
#1Shohei Mizuno (Aichi Medical University)H-Index: 8
#2Koji Kawamura (Jichi Medical University)H-Index: 9
Last.Akiyoshi Takami (Aichi Medical University)H-Index: 26
view all 18 authors...
Clinical trials evaluating the role of autologous hematopoietic stem cell transplantation (auto-HCT) in multiple myeloma have mostly included patients aged <65 years. Therefore, this study was aimed to evaluate the efficacy and safety of auto-HCT in elderly patients with multiple myeloma in the era of novel agents. We retrospectively analyzed 2056 patients with multiple myeloma, who underwent auto-HCT in 2007–2014 (287 were aged ≥65 years). We evaluated the 100-day treatment-related mortality (T...
1 CitationsSource
#1Akiyoshi Takami (Aichi Medical University)H-Index: 26
#2Tadashi Matsushita (Nagoya University)H-Index: 34
Last.Yoshiaki Tomiyama (Osaka University)H-Index: 41
view all 8 authors...
#1Yuya NakagamiH-Index: 1
#2Susumu SuzukiH-Index: 13
Last.Akiyoshi TakamiH-Index: 26
view all 11 authors...
Gnetin-C is a naturally occurring stilbene derived from the seeds of Gnetum gnemon L., an edible plant native to Southeast Asia that is called melinjo. Although the biological properties and safety of G. gnemon extract, which contains nearly 3% Gnetin-C, have been confirmed in various human studies, whether or not pure Gnetin-C is safe for humans is unclear at present. We conducted a randomized, double-blind, placebo-controlled trial. Healthy subjects were randomly divided into two groups. The i...
1 CitationsSource
#1Siqiang Gao (Aichi Medical University)
#2Akiyoshi TakamiH-Index: 26
Last.Takayuki NakayamaH-Index: 15
view all 6 authors...
Background Adipose-derived mesenchymal stem cells (ADSCs) have emerged as a promising therapeutic modality for cellular therapy because of their rapid proliferation and potent cellular activity compared to conventional bone marrow-derived mesenchymal stem cells (MSCs). Cosmetic lipoaspirates provide an easily obtainable source of ADSCs. Cryopreservation facilitates their clinical application due to increased transportability and pooling of sufficient numbers of cells. However, proper cryopreserv...
#1Kaori UchinoH-Index: 2
#2Shohei MizunoH-Index: 8
Last.Akiyoshi TakamiH-Index: 26
view all 20 authors...
#1Shingo Yano (Jikei University School of Medicine)H-Index: 13
#2Hiroki Yokoyama (Jikei University School of Medicine)H-Index: 27
Last.Akiyoshi Takami (Aichi Medical University)H-Index: 26
view all 16 authors...
Allogeneic hematopoietic stem cell transplantation (HCT) offers the most effective prevention of relapse and has significant overall survival (OS) benefits for patients with acute myeloid leukemia (AML) in first complete remission (CR1). We conducted a retrospective analysis of a cohort of patients with intermediate- or poor-risk AML. The purpose of the present study was to investigate the role of alternative donors for AML in CR1. We analyzed 1561 patients who underwent HCT from an HLA-matched ...