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Candelaria Vergara
Johns Hopkins University
60Publications
18H-index
878Citations
Publications 60
Newest
#1Michelle Daya (University of Colorado Denver)H-Index: 10
#2Nicholas Rafaels (University of Colorado Denver)H-Index: 26
Last.Kathleen C. Barnes (University of Colorado Denver)H-Index: 59
view all 65 authors...
Asthma is a complex disease with striking disparities across racial and ethnic groups. Despite its relatively high burden, representation of individuals of African ancestry in asthma genome-wide association studies (GWAS) has been inadequate, and true associations in these underrepresented minority groups have been inconclusive. We report the results of a genome-wide meta-analysis from the Consortium on Asthma among African Ancestry Populations (CAAPA; 7009 asthma cases, 7645 controls). We find ...
3 CitationsSource
#1Michelle Daya (University of Colorado Denver)H-Index: 10
#2Caapa (University of Colorado Denver)H-Index: 1
Last.Kathleen C. Barnes (University of Colorado Denver)H-Index: 59
view all 66 authors...
Source
#1Candelaria Vergara (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 18
#2Chloe L. Thio (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 45
Last.Priya Duggal (Johns Hopkins University)H-Index: 32
view all 30 authors...
Background & Aims Spontaneous clearance of hepatitis C virus (HCV) occurs in approximately 30% of infected persons and less often in populations of African ancestry. Variants in major histocompatibility complex (MHC) and in interferon lambda genes are associated with spontaneous HCV clearance, but there have been few studies of these variants in persons of African ancestry. We performed a dense multi-ancestry genome-wide association study of spontaneous clearance of HCV, focusing on individuals ...
Source
#1Rachel M. Sherman (Johns Hopkins University)H-Index: 2
#2Juliet Forman (HMC: Harvey Mudd College)H-Index: 1
Last.Steven L. SalzbergH-Index: 128
view all 46 authors...
In the version of this article initially published, the statement “there are no pan-genomes for any other animal or plant species” was incorrect. The statement has been corrected to “there are no reported pan-genomes for any other animal species, to our knowledge.” We thank David Edwards for bringing this error to our attention. The error has been corrected in the HTML and PDF versions of the article.
1 CitationsSource
#1Michelle Daya (CU: University of Colorado Boulder)H-Index: 10
#2Nicholas Rafaels (CU: University of Colorado Boulder)H-Index: 26
Last.Kathleen C. Barnes (CU: University of Colorado Boulder)H-Index: 59
view all 65 authors...
Source
#1Rachel M. Sherman (Johns Hopkins University)H-Index: 2
#2Juliet Forman (HMC: Harvey Mudd College)H-Index: 1
Last.Steven L. SalzbergH-Index: 128
view all 46 authors...
We used a deeply sequenced dataset of 910 individuals, all of African descent, to construct a set of DNA sequences that is present in these individuals but missing from the reference human genome. We aligned 1.19 trillion reads from the 910 individuals to the reference genome (GRCh38), collected all reads that failed to align, and assembled these reads into contiguous sequences (contigs). We then compared all contigs to one another to identify a set of unique sequences representing regions of th...
34 CitationsSource
#1Candelaria Vergara (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 18
#2Samantha Bomotti (Johns Hopkins University)H-Index: 1
Last.Priya Duggal (Johns Hopkins University)H-Index: 32
view all 8 authors...
Source
#1Candelaria Vergara (JHUSOM: Johns Hopkins University School of Medicine)H-Index: 18
#2Margaret M. Parker (Brigham and Women's Hospital)H-Index: 17
Last.Priya Duggal (Johns Hopkins University)H-Index: 32
view all 7 authors...
Genotype imputation estimates unobserved genotypes from genome-wide makers, to increase genome coverage and power for genome-wide association studies. Imputation has been successful for European ancestry populations in which very large reference panels are available. Smaller subsets of African descent populations are available in 1000 Genomes (1000G), the Consortium on Asthma among African ancestry Populations in the Americas (CAAPA) and the Haplotype Reference Consortium (HRC). We compared the ...
5 CitationsSource
#2Yijuan HuH-Index: 13
Last.Maria YazdanbakhshH-Index: 55
view all 19 authors...
Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome
12 CitationsSource
#1Ryan Santos Costa (UFBA: Federal University of Bahia)H-Index: 7
#2Camila Alexandrina Figueiredo (UFBA: Federal University of Bahia)H-Index: 17
Last.Kathleen C. Barnes (Johns Hopkins University)H-Index: 59
view all 13 authors...
Wellcome Trust, the HCPC Latin America Excellence Centre Programme (072405/Z/03/Z), and the Brazilian agency Conselho Nacional de Desenvolvimento Cientifico e TecnologicoeCNPq
5 CitationsSource
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