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Cristian Ibarra
Karolinska Institutet
EndocrinologyTransplantationBiochemistryBiologyCell biology
31Publications
12H-index
648Citations
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Publications 30
Newest
#1Cristian Ibarra (KI: Karolinska Institutet)H-Index: 12
#2Marie Karlsson (KI: Karolinska Institutet)H-Index: 2
Last. Per Uhlén (KI: Karolinska Institutet)H-Index: 28
view all 17 authors...
2 CitationsSource
#1Sebastian SjöqvistH-Index: 11
#2Philipp JungebluthH-Index: 21
Last. Paolo MacchiariniH-Index: 45
view all 23 authors...
Publisher Correction: Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats
Source
#1Tong Liu (Karolinska University Hospital)H-Index: 4
#2Jian Zhao (Karolinska University Hospital)H-Index: 15
Last. Monica Nistér (Karolinska University Hospital)H-Index: 46
view all 6 authors...
Abstract The Na + /Ca 2+ exchanger (NCX) is a membrane antiporter that has been identified in the plasma membrane, the inner membrane of the nuclear envelope and in the membrane of the endoplasmic reticulum (ER). In humans, three genes have been identified, encoding unique NCX proteins. Although extensively studied, the NCX’s sub-cellular localization and mechanisms regulating the activity of different subtypes are still ambiguous. Here we investigated the subcellular localization of the NCX sub...
1 CitationsSource
#1Javier Duran (University of Chile)H-Index: 3
#2Daniel Lagos (University of Chile)H-Index: 3
Last. Manuel Estrada (University of Chile)H-Index: 22
view all 9 authors...
Testosterone is known to induce cardiac hypertrophy through androgen receptor (AR)-dependent and -independent pathways, but the molecular underpinnings of the androgen action remain poorly understood. Previous work has shown that Ca2+/calmodulin-dependent protein kinase II (CaMKII) and myocyte-enhancer factor 2 (MEF2) play key roles in promoting cardiac myocyte growth. In order to gain mechanistic insights into the action of androgens on the heart, we investigated how testosterone affects CaMKII...
3 CitationsSource
#1Sebastian SjöqvistH-Index: 11
#2Philipp JungebluthH-Index: 21
Last. Paolo MacchiariniH-Index: 45
view all 23 authors...
Retraction: Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats
1 CitationsSource
#1Javier DuranH-Index: 3
#2Cesar OyarceH-Index: 5
Last. Manuel EstradaH-Index: 22
view all 10 authors...
10 CitationsSource
#1Sebastian SjöqvistH-Index: 11
#2Philipp JungebluthH-Index: 21
Last. Paolo MacchiariniH-Index: 45
view all 23 authors...
Editorial Expression of Concern: Experimental orthotopic transplantation of a tissue-engineered oesophagus in rats
Source
#1Agneta Månsson-Broberg (KI: Karolinska Institutet)H-Index: 10
#2Sergey Rodin (KI: Karolinska Institutet)H-Index: 14
Last. Karl-Henrik Grinnemo (KI: Karolinska Institutet)H-Index: 19
view all 23 authors...
The intrinsic regenerative capacity of human fetal cardiac mesenchymal stromal cells (MSCs) has not been fully characterized. Here we demonstrate that we can expand cells with characteristics of cardiovascular progenitor cells from the MSC population of human fetal hearts. Cells cultured on cardiac muscle laminin (LN)-based substrata in combination with stimulation of the canonical Wnt/β-catenin pathway showed increased gene expression of ISL1, OCT4, KDR, and NKX2.5. The majority of cells staine...
7 CitationsSource
#1Cristian IbarraH-Index: 12
#2Sergio LavanderoH-Index: 51
Last. Manuel Estrada (University of Chile)H-Index: 22
view all 3 authors...
Currently, metabolic disorders are a cardinal focus of research given their impact in public health problems worldwide. The main risk factors for death in people suffering metabolic disorders are cardiovascular diseases. Metabolic changes are important settings for cardiac cells under these conditions because the cardiovascular system must maintain energy balance to preserve work output and efficiency of the heart. Cardiovascular system is regulated by hormones which control, adjust, and remodel...
Source
#1Ivana Bulatovic (Karolinska University Hospital)H-Index: 6
#2Cristian Ibarra (KI: Karolinska Institutet)H-Index: 12
Last. Karl-Henrik Grinnemo (Karolinska University Hospital)H-Index: 19
view all 10 authors...
Generation of new cardiomyocytes is critical for cardiac repair following myocardial injury, but which kind of stimuli is most important for cardiomyocyte regeneration is still unclear. Here we explore if apoptotic stimuli, manifested through caspase activation, influences cardiac progenitor up-regulation and cardiomyocyte differentiation. Using mouse embryonic stem cells as a cellular model, we show that sublethal activation of caspases increases the yield of cardiomyocytes while concurrently p...
12 CitationsSource
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