Nita G. Forouhi
Medical Research Council
288Publications
73H-index
25.7kCitations
Publications 288
Newest
Zheng J-S.1
Estimated H-index: 1
(Medical Research Council),
Fumiaki Imamura27
Estimated H-index: 27
(Medical Research Council)
+ 36 AuthorsJ H Gómez1
Estimated H-index: 1
1 Citations Source Cite
Published on Mar 1, 2019in Public Health Nutrition 2.48
Maria Carlota Dao , Amy F. Subar80
Estimated H-index: 80
+ 6 AuthorsBridget Holmes7
Estimated H-index: 7
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Published on Jan 1, 2019in American Journal of Human Genetics 8.86
Aldi T. Kraja35
Estimated H-index: 35
(Washington University in St. Louis),
Chunyu Liu49
Estimated H-index: 49
(Boston University)
+ 149 AuthorsDaniel I. Chasman91
Estimated H-index: 91
(Harvard University)
Mitochondria (MT), the major site of cellular energy production, are under dual genetic control by 37 mitochondrial DNA (mtDNA) genes and numerous nuclear genes (MT-nDNA). In the CHARGEmtDNA+ Consortium, we studied genetic associations of mtDNA and MT-nDNA associations with body mass index (BMI), waist-hip-ratio (WHR), glucose, insulin, HOMA-B, HOMA-IR, and HbA1c. This 45-cohort collaboration comprised 70,775 (insulin) to 170,202 (BMI) pan-ancestry individuals. Validation and imputation of mtDNA...
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Published on Apr 1, 2019in Diabetes Care 13.40
Linda E.T. Vissers3
Estimated H-index: 3
(Utrecht University),
Ivonne Sluijs28
Estimated H-index: 28
(Utrecht University)
+ 33 AuthorsMaria-Dolores Chirlaque27
Estimated H-index: 27
(University of Murcia)
OBJECTIVE To estimate the causal association between intake of dairy products and incident type 2 diabetes. RESEARCH DESIGN AND METHODS The analysis included 21,820 European individuals (9,686 diabetes cases) of the EPIC-InterAct case-cohort study. Participants were genotyped, and rs4988235 (LCT-12910C>T), a SNP for lactase persistence (LP) which enables digestion of dairy sugar, i.e., lactose, was imputed. Baseline dietary intakes were assessed with diet questionnaires. We investigated the asso...
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Published on Mar 5, 2019in Nature Communications 12.35
Laura B. L. Wittemans1
Estimated H-index: 1
(University of Cambridge),
Luca A. Lotta11
Estimated H-index: 11
(University of Cambridge)
+ 20 AuthorsLixia Zeng14
Estimated H-index: 14
(Technische Universität München)
Circulating levels of glycine have previously been associated with lower incidence of coronary heart disease (CHD) and type 2 diabetes (T2D) but it remains uncertain if glycine plays an aetiological role. We present a meta-analysis of genome-wide association studies for glycine in 80,003 participants and investigate the causality and potential mechanisms of the association between glycine and cardio-metabolic diseases using genetic approaches. We identify 27 genetic loci, of which 22 have not pr...
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Published on Mar 5, 2019in Circulation 18.88
Frank Qian (Harvard University), Andres V. Ardisson Korat4
Estimated H-index: 4
(Harvard University)
+ 20 AuthorsYoichiro Hirakawa25
Estimated H-index: 25
(Kyushu University)
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Published on Apr 1, 2019in Nature Genetics 27.13
Amy R. Bentley13
Estimated H-index: 13
(National Institutes of Health),
Yun J. Sung5
Estimated H-index: 5
(Washington University in St. Louis)
+ 298 AuthorsXuan Deng3
Estimated H-index: 3
(Boston University)
The concentrations of high- and low-density-lipoprotein cholesterol and triglycerides are influenced by smoking, but it is unknown whether genetic associations with lipids may be modified by smoking. We conducted a multi-ancestry genome-wide gene–smoking interaction study in 133,805 individuals with follow-up in an additional 253,467 individuals. Combined meta-analyses identified 13 new loci associated with lipids, some of which were detected only because association differed by smoking status. ...
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Published on Feb 1, 2018in American Journal of Human Genetics 8.86
Yun J. Sung5
Estimated H-index: 5
(Washington University in St. Louis),
Thomas W. Winkler23
Estimated H-index: 23
(University of Regensburg)
+ 294 AuthorsNora Franceschini47
Estimated H-index: 47
(University of North Carolina at Chapel Hill)
Genome-wide association analysis advanced understanding of blood pressure (BP), a major risk factor for vascular conditions such as coronary heart disease and stroke. Accounting for smoking behavior may help identify BP loci and extend our knowledge of its genetic architecture. We performed genome-wide association meta-analyses of systolic and diastolic BP incorporating gene-smoking interactions in 610,091 individuals. Stage 1 analysis examined ∼18.8 million SNPs and small insertion/deletion var...
12 Citations Source Cite
Published on Apr 1, 2018in The Lancet 53.25
Angela M. Wood31
Estimated H-index: 31
(University of Cambridge),
Stephen Kaptoge47
Estimated H-index: 47
(University of Cambridge)
+ 128 AuthorsStephen Burgess37
Estimated H-index: 37
(University of Cambridge)
Summary Background Low-risk limits recommended for alcohol consumption vary substantially across different national guidelines. To define thresholds associated with lowest risk for all-cause mortality and cardiovascular disease, we studied individual-participant data from 599 912 current drinkers without previous cardiovascular disease. Methods We did a combined analysis of individual-participant data from three large-scale data sources in 19 high-income countries (the Emerging Risk Factors Coll...
69 Citations Source Cite
Published on Jun 1, 2018in Diabetes 7.27
Janine Kröger23
Estimated H-index: 23
,
Karina Meidtner14
Estimated H-index: 14
+ 40 AuthorsCourtney Dow5
Estimated H-index: 5
(French Institute of Health and Medical Research)
Fetuin-A, a hepatic-origin protein, is strongly positively associated with risk of type 2 diabetes in human observational studies, but it is unknown whether this association is causal. We aimed to study the potential causal relation of circulating fetuin-A to risk of type 2 diabetes in a Mendelian Randomization study with SNPs located in the fetuin-A-encoding AHSG gene. We used data from eight European countries of the prospective EPIC-InterAct case-cohort study including 10,020 incident cases. ...
1 Citations Source Cite
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