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Vatsalya Vatsalya
University of Louisville
37Publications
7H-index
128Citations
Publications 39
Newest
Abstract Background & Aims: Acute alcoholic hepatitis (AAH) is a major cause of liver-related morbidity and mortality; there are no good blood biomarkers for diagnosis or determining magnitude of cell death. Keratin 18 (KRT18, also called K18), found in epithelial cells, is released from hepatocytes upon death. We investigated whether level of K18 is a better marker of hepatocyte death than standard biomarkers and might be used to identify patients with AAH at risk for death within 90 days. Meth...
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Alcohol hangover is a combination of mental, sympathetic, and physical symptoms experienced the day after a single period of heavy drinking, starting when blood alcohol concentration approaches zero. How individual measures/domains of hangover symptomology might differ with moderate to heavy alcohol consumption and how these symptoms correlate with the drinking markers is unclear. We investigated the amount/patterns of drinking and hangover symptomology by the categories of alcohol drinking. We ...
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#1Vatsalya VatsalyaH-Index: 7
#2Maiying Kong (University of Louisville)H-Index: 19
Last.Swati Joshi-BarveH-Index: 4
view all 8 authors...
This is the first study to examine the urinary acrolein metabolite 3-hydroxypropylmercapturic acid (HPMA) in alcoholic liver disease. HPMA was higher in patients with severe acute alcoholic hepatit...
2 CitationsSource
#1Yun Zhou (University of Louisville)H-Index: 2
#2Vatsalya VatsalyaH-Index: 7
Last.Wenke FengH-Index: 31
view all 6 authors...
2 CitationsSource
#1Vatsalya VatsalyaH-Index: 7
#2Maiying Kong (University of Louisville)H-Index: 19
Last.Craig J. McClainH-Index: 66
view all 8 authors...
Abstract Zinc deficiency is a frequent complication of alcohol abuse for multiple reasons including poor intake, increased excretion, internal redistribution and altered transporters. Zinc deficiency has been postulated to play a role in the development/progression of alcoholic liver disease (ALD). This study aimed to relate serum zinc levels with alcohol intake, serum albumin concentration and markers of inflammation and liver injury. One hundred and eight male and female very heavy drinking (≥...
3 CitationsSource
#1Irina A. KirpichH-Index: 17
#2Vatsalya VatsalyaH-Index: 7
Last.Craig J. McClainH-Index: 66
view all 6 authors...
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#1Vatsalya VatsalyaH-Index: 7
#2Leila GobejishviliH-Index: 13
Last.Swati Joshi-BarveH-Index: 22
view all 7 authors...
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Objectives: Diagnostics is the first step for the treatment and eradication of infectious microbial diseases. Due to ever evolving pathogens and emerging new diseases, there is an urgent need to identify suitable diagnostic techniques for better management of each disease. The success rate of specific diagnostic technique in any population depends on various factors including type of the microbial pathogen, availability of resources, technical expertise, disease severity and degree of epidemic o...
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