Elani Streja
University of California, Irvine
Intensive care medicineHemodialysisDialysisDiabetes mellitusMedicine
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Publications 241
#1Melissa SoohooH-Index: 15
#2Cynthia A. Jackevicius (UWO: University of Western Ontario)H-Index: 34
Last. Elani StrejaH-Index: 36
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#1Paungpaga Lertdumrongluk (SWU: Srinakharinwirot University)H-Index: 8
#2Ekamol Tantisattamo (UCI: University of California, Irvine)H-Index: 5
Last. Elani Streja (UCI: University of California, Irvine)H-Index: 36
view all 8 authors...
BACKGROUND: Higher estimated glomerular filtration rate (eGFR) at dialysis initiation, known as earlier start of dialysis, is often a surrogate of poor outcomes including higher mortality. We hypothesized that earlier dialysis initiation is associated with a faster decline in residual kidney function (RKF), which is also associated with higher mortality among incident hemodialysis (HD) patients. METHODS: In a cohort of 4911 incident HD patients who initiated HD over a 5-year period (July 2001 to...
#1Christopher Reist (UCI: University of California, Irvine)H-Index: 31
#2Elani Streja (UCI: University of California, Irvine)H-Index: 36
Last. Michael HollifieldH-Index: 4
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BACKGROUND.: Prazosin has been an accepted treatment for patients with post-traumatic stress disorder (PTSD) who experience sleep disturbances, including nightmares. Results of a recent large randomized control trial did not find benefit of prazosin vs placebo in improving such outcomes. A meta-analysis that includes this most recent trial was conducted to examine the pooled effect of prazosin vs placebo on sleep disturbances and overall PTSD symptoms in patients with PTSD. METHODS.: A systemati...
#1Amy S. You (UCI: University of California, Irvine)H-Index: 6
#2Kamyar Kalantar-Zadeh (UCI: University of California, Irvine)H-Index: 96
Last. Connie M. Rhee (UCI: University of California, Irvine)H-Index: 28
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Abstract Introduction While residual urine output (UOP) is associated with better survival and quality of life in dialysis patients, frequent measurement by 24-hour urine collection is burdensome. We thus sought to examine the association of patients’ self-reported residual UOP, as an alternative proxy of measured residual UOP, with mortality risk in a prospective hemodialysis cohort study. Methods Among 670 hemodialysis patients from the prospective multi-center Malnutrition, Diet, and Racial D...
#1Elvira O. Gosmanova (Albany Medical College)H-Index: 12
#2Miklos Z. Molnar (Methodist University)H-Index: 3
Last. Kamyar Kalantar-Zadeh (UCI: University of California, Irvine)H-Index: 96
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Abstract Background Angiotensin converting enzyme inhibitors and angiotensin receptor blockers (ACEi/ARB) improve predialysis outcomes; however, ACEi/ARB are underutilized in patients transitioning to dialysis. We examined the association of different patterns of predialysis ACEi/ARB use with postdialysis survival, and whether potentially modifiable adverse events are associated with lower predialysis ACEi/ARB utilization. Methods This was a historic cohort study of 34,676 US veterans with, and ...
#2Neda NaderiH-Index: 2
Last. Connie M. RheeH-Index: 28
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Abstract Background Serum albumin (sAlb) may be a strong predictor of longevity in the general population and in chronic kidney disease. Objective To determine the relationship between sAlb concentrations and mortality risk independent of kidney function. Methods Retrospective cohort study of 31,274 adults from the 1999-2010 National Health and Nutrition Examination Survey. Estimated glomerular filtration rate (eGFR) was examined as both a confounder and modifier of the association of sAlb with ...
#1Gang Jee Ko (KU: Korea University)H-Index: 3
#2Connie M. Rhee (UCI: University of California, Irvine)H-Index: 28
Last. Kamyar Kalantar-Zadeh (UCI: University of California, Irvine)H-Index: 96
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Author(s): Ko, Gang Jee; Rhee, Connie M; Obi, Yoshitsugu; Chang, Tae Ik; Soohoo, Melissa; Kim, Tae Woo; Kovesdy, Csaba P; Streja, Elani; Kalantar-Zadeh, Kamyar | Abstract: Arteriovenous fistulas (AVFs) are the preferred vascular access type in most hemodialysis patients. However, the optimal vascular access type in octogenarians and older (≥80 years) hemodialysis patients remains widely debated given their limited life expectancy and lower AVF maturation rates.Among incident hemodialysis patient...
2 CitationsSource
#1John Sy (UCI: University of California, Irvine)H-Index: 2
#2Elani Streja (UCI: University of California, Irvine)H-Index: 36
Last. Kirsten L. Johansen (UCSF: University of California, San Francisco)H-Index: 51
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Abstract: Introduction Dialysis patients incur disproportionately high costs compared with other Medicare beneficiaries. Care for frail individuals may be even more costly. We examined the extent to which frailty contributes to higher costs among dialysis patients. Methods We utilized ACTIVE/ADIPOSE enrollees (adult hemodialysis patients evaluated from June 2009 to August 2011) in a retrospective cohort analysis. Individuals utilizing Medicare as the primary payer were included. Fried’s frailty ...
#1Yu-Ji Lee (SKKU: Sungkyunkwan University)
#2Yusuke Okuda (UCI: University of California, Irvine)H-Index: 1
Last. Elani Streja (UCI: University of California, Irvine)H-Index: 36
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Rationale & Objective Patients receiving twice-weekly or less-frequent hemodialysis (HD) may need to undergo higher ultrafiltration rates (UFRs) to maintain acceptable fluid balance. We hypothesized that higher UFRs are associated with faster decline in residual kidney function (RKF) and a higher rate of mortality. Study Design Retrospective cohort study. Setting & Participants 1,524 patients with kidney failure who initiated maintenance HD at a frequency of twice or less per week for at least 6...
1 CitationsSource
#1Duk-Hee Kang (Ewha Womans University)H-Index: 1
#2Yu-Ji Lee (SKKU: Sungkyunkwan University)
Last. Elani Streja (UCI: University of California, Irvine)H-Index: 36
view all 10 authors...
BACKGROUND: Eosinophils are traditionally known as moderators of allergic reactions; however, they have now emerged as one of the principal immune-regulating cells as well as predictors of vascular disease and mortality in the general population. Although eosinophilia has been demonstrated in hemodialysis (HD) patients, associations of eosinophil count (EOC) and its changes with mortality in HD patients are still unknown. METHODS: In 107 506 incident HD patients treated by a large dialysis organ...