Daniel B. Larremore
University of Colorado Boulder
Adjacency matrixPopulationMathematicsComplex networkComputer science
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Publications 35
#1Stephen M. KisslerH-Index: 4
#2Nishant KishoreH-Index: 1
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#1Daniel B. LarremoreH-Index: 14
#2Kate M. BubarH-Index: 1
Last. Yonatan H. GradH-Index: 21
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#1Daniel B. Larremore (CU: University of Colorado Boulder)H-Index: 14
#2Bailey K. Fosdick (CSU: Colorado State University)H-Index: 11
Last. Yonatan H. Grad (Harvard University)H-Index: 21
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Establishing how many people have already been infected by SARS-CoV-2 is an urgent priority for controlling the COVID-19 pandemic. Patchy virological testing has hampered interpretation of confirmed case counts, and unknown rates of asymptomatic and mild infections make it challenging to develop evidence-based public health policies. Serological tests that identify past infection can be used to estimate cumulative incidence, but the relative accuracy and robustness of various sampling strategies...
2 CitationsSource
#1Nyamekye Obeng-Adjei (NIH: National Institutes of Health)H-Index: 6
#2Daniel B. Larremore (CU: University of Colorado Boulder)H-Index: 14
Last. Boubacar Traore (University of the Sciences)H-Index: 17
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Malaria pathogenicity is determined, in part, by the adherence of Plasmodium falciparum infected erythrocytes to the microvasculature mediated via specific interactions between PfEMP1 variant domains to host endothelial receptors. Naturally acquired antibodies against specific PfEMP1 variants can play an important role in clinical protection against malaria. We evaluated IgG responses against a repertoire of PfEMP1 CIDR domain variants to determine the rate and order of variant-specific antibody...
In bipartite networks, community structures are restricted to being disassortative, in that nodes of one type are grouped according to common patterns of connection with nodes of the other type. This makes the stochastic block model (SBM), a highly flexible generative model for networks with block structure, an intuitive choice for bipartite community detection. However, typical formulations of the SBM do not make use of the special structure of bipartite networks. In this work, we introduce a B...
#1Amy K. BeiH-Index: 19
#2Daniel B. LarremoreH-Index: 14
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As transmission intensity has declined in Senegal, so has the genetic complexity of circulating Plasmodium falciparum parasites, resulting in specific genotypes emerging and persisting over years. We address whether changes in parasite genetic signatures can alter the immune repertoire to variant surface antigens, and whether such responses can influence the expansion or contraction of specific parasite genotypes in the population. We characterize parasites within genotypic clusters, defined as ...
Experiments suggest that cerebral cortex gains several functional advantages by operating in a dynamical regime near the critical point of a phase transition. However, a long-standing criticism of this hypothesis is that critical dynamics are rather noisy, which might be detrimental to aspects of brain function that require precision. If the cortex does operate near criticality, how might it mitigate the noisy fluctuations? One possibility is that other parts of the brain may act to control the ...
#1Samuel F. WayH-Index: 7
#2Allison C. MorganH-Index: 2
Last. Aaron Clauset (CU: University of Colorado Boulder)H-Index: 30
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Faculty at prestigious institutions produce more scientific papers, receive more citations and scholarly awards, and are typically trained at more-prestigious institutions than faculty with less prestigious appointments. This imbalance is often attributed to a meritocratic system that sorts individuals into more-prestigious positions according to their reputation, past achievements, and potential for future scholarly impact. Here, we investigate the determinants of scholarly productivity and mea...
#1Daniel B. Larremore (CU: University of Colorado Boulder)H-Index: 14
Measuring the overlap between two populations is, in principle, straightforward. Upon fully sampling both populations, the number of shared objects—species, taxonomical units, or gene variants, depending on the context—can be directly counted. In practice, however, only a fraction of each population’s objects are likely to be sampled due to stochastic data collection or sequencing techniques. Although methods exists for quantifying population overlap under subsampled conditions, their bias is we...
#1Vidit Agrawal (UA: University of Arkansas)H-Index: 1
#2Andrew B. Cowley (CU: University of Colorado Boulder)H-Index: 1
Last. Woodrow L. Shew (UA: University of Arkansas)H-Index: 20
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It is widely appreciated that balanced excitation and inhibition are necessary for proper function in neural networks. However, in principle, balance could be achieved by many possible configurations of excitatory and inhibitory synaptic strengths and relative numbers of excitatory and inhibitory neurons. For instance, a given level of excitation could be balanced by either numerous inhibitory neurons with weak synapses or a few inhibitory neurons with strong synapses. Among the continuum of dif...
2 CitationsSource