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Rebecca Spencer
University College London
16Publications
4H-index
112Citations
Publications 16
Newest
#1Merryl Harvey (BCU: Birmingham City University)H-Index: 6
#2Anna L. David (UCL: University College London)H-Index: 30
Last.Rebecca Spencer (UCL: University College London)H-Index: 4
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Background The EVERREST Prospective Study is a multicentre observational cohort study of pregnancies affected by severe early-onset fetal growth restriction. The study recruits women with singleton pregnancies where the estimated fetal weight is less than the 3rd centile and below 600 g, between 20 + 0 and 26 + 6 weeks of pregnancy, in the absence of a known chromosomal, structural or infective cause.
Source
#1Rebecca Spencer (UCL: University College London)H-Index: 4
#2C Rossi (UCL: University College London)H-Index: 3
Last.Anna L. David (UCL: University College London)H-Index: 30
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Source
#1Merryl HarveyH-Index: 6
#2Anna L. DavidH-Index: 30
Last.Rebecca SpencerH-Index: 4
view all 4 authors...
Abstract Background: The EVERREST Prospective Study is a multicentre observational cohort study of pregnancies affected by severe early-onset fetal growth restriction. The study recruits women with singleton pregnancies where the estimated fetal weight is less than the 3rd centile and below 600 g, between 20 + 0 and 26 + 6 weeks of pregnancy, in the absence of a known chromosomal, structural or infective cause. Method: The reported study was retrospective descriptive qualitative interview study ...
#1Rosalind AughwaneH-Index: 3
#2Magdalena SokolskaH-Index: 5
Last.Anna L. DavidH-Index: 30
view all 14 authors...
#1Rebecca SpencerH-Index: 4
#2Dj CarrH-Index: 8
Last.Anna L. DavidH-Index: 30
view all 3 authors...
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Source
#1Andrew Sharp (University of Liverpool)H-Index: 10
#2Christine Cornforth (University of Liverpool)H-Index: 1
Last.G. J. BuggH-Index: 5
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Summary Background Severe early-onset fetal growth restriction can lead to a range of adverse outcomes including fetal or neonatal death, neurodisability, and lifelong risks to the health of the affected child. Sildenafil, a phosphodiesterase type 5 inhibitor, potentiates the actions of nitric oxide, which leads to vasodilatation of the uterine vessels and might improve fetal growth in utero. Methods We did this superiority, placebo-controlled randomised trial in 19 fetal medicine units in the U...
43 CitationsSource
#1Rebecca Spencer (UCL: University College London)H-Index: 4
#2Gareth Ambler (UCL: University College London)H-Index: 27
Last.Anna L. David (UCL: University College London)H-Index: 30
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Fetal growth restriction (FGR) is a serious obstetric condition for which there is currently no treatment. The EVERREST Prospective Study has been designed to characterise the natural history of pregnancies affected by severe early onset FGR and establish a well phenotyped bio-bank. The findings will provide up-to-date information for clinicians and patients and inform the design and conduct of the EVERREST Clinical Trial: a phase I/IIa trial to assess the safety and efficacy of maternal vascula...
18 CitationsSource
#1Sarah Rae Easter (Brigham and Women's Hospital)H-Index: 5
#2Linda O. Eckert (UW: University of Washington)H-Index: 19
Last.Tom McElrath (Brigham and Women's Hospital)H-Index: 1
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2 CitationsSource
#1Rebecca SpencerH-Index: 4
#2Neil J. SebireH-Index: 70
Last.Anna L. DavidH-Index: 30
view all 6 authors...
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