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Wah Cheuk
60Publications
30H-index
4,470Citations
Publications 60
Newest
Published on Jun 15, 2014in Clinical Cancer Research8.91
Shuangping Guo5
Estimated H-index: 5
,
John K. C. Chan79
Estimated H-index: 79
+ 10 AuthorsRuian Wang1
Estimated H-index: 1
(Fourth Military Medical University)
Purpose: Gain-of-function mutations of enhancer of Zeste homolog 2 ( EZH2 ) occur frequently in diffuse large B-cell lymphomas and in follicular lymphomas. However, the frequency of EZH2 mutation in Chinese follicular lymphomas and the potential targets affected by this mutation are unknown. Experimental Design: We determined EZH2 codon 641 mutations in Chinese follicular lymphomas ( n = 124) and compared them with Western follicular lymphomas ( n = 70) using a sensitive pyrosequencing assay. Ge...
Published on Oct 1, 2013in International Journal of Surgical Pathology0.97
John K. C. Chan79
Estimated H-index: 79
,
Yiu-Tung Ip3
Estimated H-index: 3
(Tuen Mun Hospital),
Wah Cheuk30
Estimated H-index: 30
With advances in immunohistochemical technology and growing knowledge of the molecular genetics of tumors, immunohistochemistry is playing an increasingly important role in providing genetic information for tumors. Specific chromosomal translocations can be demonstrated through detection of the protein product of one of the genes involved in gene fusion (such as BCL2, cyclin D, and ALK). Some mutations can be detected by (1) aberrant localization of the protein product (such as β-catenin and nuc...
Published on Nov 1, 2012in Seminars in Diagnostic Pathology2.08
Wah Cheuk30
Estimated H-index: 30
,
John K.C. Chan2
Estimated H-index: 2
Lymphadenopathy is a common occurrence in IgG4-related disease; it can appear before, concurrent with, or after the diagnosis of this disease, which is characterized by tumefactive sclerosing inflammatory lesions predominantly affecting extranodal sites, such as the pancreas, salivary gland, and lacrimal gland. Although multiple lymph node groups are commonly involved, constitutional symptoms are absent. The lymph nodes can show a broad morphologic spectrum, including multicentric Castleman dise...
Published on Oct 1, 2012in Arthritis & Rheumatism9.00
John H. Stone67
Estimated H-index: 67
(Harvard University),
Arezou Khosroshahi25
Estimated H-index: 25
(Harvard University)
+ 36 AuthorsMollie N. Carruthers15
Estimated H-index: 15
(Harvard University)
John H. Stone, Arezou Khosroshahi, Vikram Deshpande, John K. C. Chan, J. Godfrey Heathcote, Rob Aalberse, Atsushi Azumi, Donald B. Bloch, William R. Brugge, Mollie N. Carruthers, Wah Cheuk, Lynn Cornell, Carlos Fernandez-Del Castillo, Judith A. Ferry, David Forcione, Gunter Kloppel, Daniel L. Hamilos, Terumi Kamisawa, Satomi Kasashima, Shigeyuki Kawa, Mitsuhiro Kawano, Yasufumi Masaki, Kenji Notohara, Kazuichi Okazaki, Ji Kon Ryu, Takako Saeki, Dushyant Sahani, Yasuharu Sato, Thomas Smyrk, James...
Published on Oct 1, 2012in The American Journal of Surgical Pathology6.16
Wah Cheuk30
Estimated H-index: 30
,
William Y.W. Tsang25
Estimated H-index: 25
,
John K. C. Chan79
Estimated H-index: 79
Published on Sep 1, 2012in Modern Pathology6.37
Vikram V. Deshpande85
Estimated H-index: 85
(Harvard University),
Yoh Zen62
Estimated H-index: 62
(University of Cambridge)
+ 38 AuthorsJudith A. Ferry57
Estimated H-index: 57
(Harvard University)
IgG4-related disease is a newly recognized fibro-inflammatory condition characterized by several features: a tendency to form tumefactive lesions in multiple sites; a characteristic histopathological appearance; and-often but not always-elevated serum IgG4 concentrations. An international symposium on IgG4-related disease was held in Boston, MA, on 4-7 October 2011. The organizing committee comprising 35 IgG4-related disease experts from Japan, Korea, Hong Kong, the United Kingdom, Germany, Ital...
Published on Nov 1, 2011in International Journal of Gynecological Pathology2.01
Wah Cheuk30
Estimated H-index: 30
,
Ian Beavon1
Estimated H-index: 1
+ 1 AuthorsJohn K. C. Chan79
Estimated H-index: 79
Solid pseudopapillary neoplasm, an uncommon, intriguing, low-grade malignant tumor of the pancreas, can exceptionally occur in extrapancreatic sites. We report 1 such case occurring as an ovarian primary in a 25-year-old woman, who presented with abdominal fullness. She remained well 12 years after resection of the 1.7-kg right ovarian tumor. Histologically, the tumor showed a solid, dehiscent, and pseudopapillary growth, traversed by fibrous septa and arborizing blood vessels. The polygonal tum...
Published on May 1, 2011in International Journal of Gynecological Pathology2.01
Gang Chen7
Estimated H-index: 7
,
Wah Cheuk30
Estimated H-index: 30
+ 1 AuthorsJohn K. C. Chan79
Estimated H-index: 79
Carcinosarcoma is exceedingly rare in the vulva. We describe a case of carcinosarcoma in a 67-year-old female patient who presented with recent enlargement and pain of a vulval nodule noted for 15 years. The excised tumor showed intermixed carcinomatous (adenocarcinoma and anaplastic carcinoma) and sarcomatous elements (osteosarcoma, chondrosarcoma, and leiomyosarcoma), which focally merged with several lobules of typical eccrine spiradenoma. The inguinal lymph nodes showed metastasis of the car...
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