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Robert C. Noland
Pennington Biomedical Research Center
Publications 43
Published on May 16, 2019in Journal of Biological Chemistry
Sujoy Ghosh33
Estimated H-index: 33
(Pennington Biomedical Research Center),
Shawna E. Wicks8
Estimated H-index: 8
+ 7 AuthorsRobert C. Noland18
Estimated H-index: 18
(Pennington Biomedical Research Center)
Published on May 1, 2019in Metabolism-clinical and Experimental 6.51
Randall L. Mynatt29
Estimated H-index: 29
Robert C. Noland18
Estimated H-index: 18
+ 6 AuthorsJaycob D. Warfel4
Estimated H-index: 4
Abstract Background Metabolic flexibility can be assessed by changes in respiratory exchange ratio (RER) following feeding. Though metabolic flexibility (difference in RER between fasted and fed state) is often impaired in individuals with obesity or type 2 diabetes, the cellular processes contributing to this impairment are unclear. Materials and methods From several clinical studies we identified the 16 most and 14 least metabolically flexible male and female subjects out of >100 participants ...
Tai-Yu Huang2
Estimated H-index: 2
Felicia R. Goldsmith + -3 AuthorsChristopher D. Morrison32
Estimated H-index: 32
ABSTRACTPurposeStudies suggest ketogenic diets (KDs) produce favorable outcomes (health and exercise performance); however, most rodent studies have used a low protein KD, which does not reflect the normal-to-high protein KDs used by humans. Liver has an important role in ketoadaptation due to its i
Published on May 16, 2019in Journal of Applied Physiology 3.14
Scott Fuller3
Estimated H-index: 3
(Pennington Biomedical Research Center),
Scott Fuller (University of Louisiana at Lafayette)+ 8 AuthorsJohn M. Brown (Pennington Biomedical Research Center)
Effects of low-intensity exercise on substrate metabolism pathways were tested in liver and skeletal muscle of healthy mice. This is the first study to describe exercise-induced adaptations in pero...
Published on Jun 1, 2019in Diabetes 7.20
William T. King , Christopher L. Axelrod2
Estimated H-index: 2
+ 2 AuthorsJohn P. Kirwan54
Estimated H-index: 54
Introduction: Mitochondria are organelles that routinely undergo fission and fusion in a process known as mitochondrial dynamics. Increased mitochondrial fission is implicated in the pathogenesis of obesity, type 2 diabetes, and metabolic disease. DRP1 has been identified as a key regulator of mitochondrial fission. We and others have demonstrated that loss of DRP1 is associated with improvements in glucose homeostasis, however, the role of DRP1 in mitochondrial fatty acid oxidation is unknown. ...
Published on Apr 1, 2019in Diabetes 7.20
Claudia Kruger9
Estimated H-index: 9
(Pennington Biomedical Research Center),
Trang-Tiffany Nguyen1
Estimated H-index: 1
(Pennington Biomedical Research Center)
+ 8 AuthorsRandall L. Mynatt29
Estimated H-index: 29
(Pennington Biomedical Research Center)
Proximal tubular epithelial cells are highly energy demanding. Their energy need is covered mostly from mitochondrial fatty acid oxidation. Whether derailments in fatty acid metabolism and mitochondrial dysfunction are forerunners of tubular damage has been suggested but is not entirely clear. Here we modeled mitochondrial overload by creating mice lacking the enzyme carnitine acetyltransferase (CrAT) in the proximal tubules, thus limiting a primary mechanism to export carbons under conditions o...
Published on Mar 12, 2019in British Journal of Sports Medicine 11.64
Robert Ross47
Estimated H-index: 47
(UM: University of Michigan),
Bret H. Goodpaster80
Estimated H-index: 80
(Translational Research Institute)
+ 13 AuthorsAlex Castro1
Estimated H-index: 1
(State University of Campinas)
There is evidence from human twin and family studies as well as mouse and rat selection experiments that there are considerable interindividual differences in the response of cardiorespiratory fitness (CRF) and other cardiometabolic traits to a given exercise programme dose. We developed this consensus statement on exercise response variability following a symposium dedicated to this topic. There is strong evidence from both animal and human studies that exercise training doses lead to variable ...
Published on Jul 1, 2018in Obesity 3.97
Susan J. Burke8
Estimated H-index: 8
(Pennington Biomedical Research Center),
Heidi M. Batdorf2
Estimated H-index: 2
(Pennington Biomedical Research Center)
+ 6 AuthorsJ. Jason Collier16
Estimated H-index: 16
(Pennington Biomedical Research Center)
Published on Apr 1, 2018in Molecular Nutrition & Food Research 4.65
Yongmei Yu11
Estimated H-index: 11
(Pennington Biomedical Research Center),
Tamra Mendoza8
Estimated H-index: 8
(Pennington Biomedical Research Center)
+ 6 AuthorsZ. Elizabeth Floyd23
Estimated H-index: 23
(Pennington Biomedical Research Center)