F. Zani
University of Parma
Organic chemistryChemistryAntimicrobialBiochemistryLigand
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Publications 45
#1Claudia Huedo (UAM: Autonomous University of Madrid)
#2F. ZaniH-Index: 20
Last. Elena López-Torres (UAM: Autonomous University of Madrid)H-Index: 14
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#1Cristina González-García (UAM: Autonomous University of Madrid)H-Index: 2
#2Alejandro Mata (UAM: Autonomous University of Madrid)H-Index: 1
Last. Elena López-Torres (UAM: Autonomous University of Madrid)H-Index: 14
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Abstract Four novel ligands derived from 2,3-butanedione have been synthesized, two dissymmetric thiosemicarbazone/3-hydroxy-2-naphthohydrazone ligands, H 2 L 1 (bearing 4-isopropyl-3-thiosemicarbazone) and H 2 L 2 (containing 4-cyclohexyl-3-thiosemicarbazone) and the symmetric H 2 L 3 , diacetyl bis(3-hydroxy-2-naphthohydrazone), and H 2 L 4 , diacetyl bis(4-cyclohexyl-3-thiosemicarbazone). Their reactivity with SnR 2 Cl 2 (R = methyl, n -butyl and phenyl) was explored and the resulting complex...
9 CitationsSource
#1F. Zani (University of Parma)H-Index: 20
#2Cristina VenezianiH-Index: 1
Last. Ruggero Bettini (University of Parma)H-Index: 32
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Abstract Glucocorticosteroids, a class of drugs widely used in the treatment of allergies, airways inflammation and inflammatory ocular diseases, are often difficult to sterilize due to their inherent sensibility to heat or irradiation induced degradation. Being often in form of suspension, obviously the final medicinal product cannot be sterilized by filtration. The effectiveness of supercritical CO 2 (SC-CO 2 ) based method for the sterilization of food and biomedical materials is well documen...
9 CitationsSource
#1Stefano Barbieri (University of Parma)H-Index: 14
#2Fabio Sonvico (University of Parma)H-Index: 22
Last. Paolo Colombo (University of Parma)H-Index: 47
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Abstract Tamoxifen citrate (TAM), an anticancer drug with amphiphilic properties, was loaded in lecithin/chitosan nanoparticles (LCN) with a view to oral administration. The influence of tamoxifen loading on the physico-chemical properties of nanoparticles was studied. Size, surface charge and morphological properties of tamoxifen-loaded nanoparticles (LCN-TAM) were assessed. The increase in the tamoxifen amount in the LCN-TAM preparation up to 60 mg/100ml maintained the positive zeta potential ...
27 CitationsSource
#1F. ZaniH-Index: 20
Last. Ruggero BettiniH-Index: 32
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Three types of palladium(II) halide complexes of quinolinylaminophosphonates have been synthesized and studied. Diethyl and dibutyl [alpha-anilino-(quinolin-2-ylmethyl)]phosphonates (L1, L2) act as N, N-chelate ligands through the quinoline and aniline nitrogens giving complexes cis-[Pd(L1/L2)X2] (X=Cl, Br) (1-4). Their 3-substituted analogues [alpha-anilino-(quinolin-3-ylmethyl)]phosphonates (L3, L4) form dihalidopalladium complexes trans-[Pd(L3/L4)2X2] (5-8), with trans N-bonded ligand molecul...
41 CitationsSource
#1Elena López-Torres (UAM: Autonomous University of Madrid)H-Index: 14
#2F. ZaniH-Index: 20
Last. M. Antonia Mendiola (UAM: Autonomous University of Madrid)H-Index: 12
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Several methyltin(IV) and butyltin(IV) complexes with the ligand benzil bis (benzoylhydrazone) and 4,4′-bipyridyl as coligand were synthesised and characterized by elemental analysis and by IR, 1 H, 13 C and 119 Sn NMR spectroscopies. Some of them were also analyzed using single crystal X-ray diffraction. The title compounds were evaluated for their in vitro antimicrobial properties. All buthyltin complexes showed significant inhibition of Gram positive bacteria, resulting Bacillus subtilis , Sa...
22 CitationsSource
#1Stefania BenvenutiH-Index: 25
#2F. SeveriH-Index: 5
Last. L. AntoliniH-Index: 8
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#1Truc Thanh Ngoc Huynh (University of Lyon)H-Index: 2
#2Karine Padois (University of Lyon)H-Index: 7
Last. Françoise Falson (University of Lyon)H-Index: 21
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Abstract Conventional formulations of chlorhexidine usually provide short-term efficiency, requiring repeated applications to maintain antibacterial activity. Therefore, appropriate release system of chlorhexidine controlling local drug delivery would reduce the number of applications and enhance patient compliance. The aim of this study was to develop a controlled release system based on medical polyurethane for the local delivery of chlorhexidine diacetate (CDA). CDA-loaded polyurethane films ...
35 CitationsSource
#1María C. Rodríguez-Argüelles (University of Vigo)H-Index: 20
#2Sandra Mosquera-Vázquez (University of Vigo)H-Index: 4
Last. F. Zani (University of Parma)H-Index: 20
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Abstract Some first row transition metal(II) complexes of imidazole-2-carbaldehyde semicarbazone (H2L) have been synthesised and characterised. Single crystal X-ray diffraction studies have revealed the molecular structure of the neutral complex NiCl2(H2L)(H2O). This latter complex shows a pseudo-octahedral geometry, with both chloride ions displaying a cis disposition. The asymmetry of this complex allows the formation of two enantiomers in the racemic crystal structure. The non-deprotonated se...
23 CitationsSource