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Eric J. Charles
University of Virginia Health System
68Publications
10H-index
298Citations
Publications 73
Newest
#1William J. Kane (UVA: University of Virginia)H-Index: 1
#2Eric J. Charles (UVA: University of Virginia)H-Index: 10
Last.Zequan Yang (UVA: University of Virginia)H-Index: 28
view all 7 authors...
Abstract Background As robotic surgery becomes more ubiquitous, determining clinical benefit is necessary to justify the cost and time investment required to become proficient. We hypothesized that robotic cholecystectomy would be associated with improved clinical outcomes but also increased cost as compared with standard laparoscopic cholecystectomy. Materials and Methods All patients undergoing robotic or laparoscopic cholecystectomy at a single academic hospital between 2007 and 2017 were ide...
1 CitationsSource
#1Eric J. Charles (UVA: University of Virginia)H-Index: 10
#2Mahendra D. Chordia (UVA: University of Virginia)H-Index: 19
Last.Victor E. Laubach (UVA: University of Virginia)H-Index: 40
view all 12 authors...
Primary graft dysfunction after lung transplantation, a consequence of ischemia-reperfusion injury (IRI), is a major cause of morbidity and mortality. IRI involves acute inflammation and innate imm...
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#1Eric J. Charles (UVA: University of Virginia)H-Index: 10
#2William J. Kane (UVA: University of Virginia)H-Index: 1
Last.Robert G. Sawyer (UVA: University of Virginia)H-Index: 48
view all 6 authors...
Abstract Optimal calorie goals for adult, obese critically ill surgical patients are unclear. To date, there has been little data comparing feeding regimens for obese and non-obese critically ill surgical patients and the effect on outcomes. The objective was to compare the effect of hypocaloric and eucaloric feeding goals in critically ill obese patients on outcomes, including infection, intensive care unit (ICU) length of stay, and mortality. We hypothesized that hypocaloric feeding of patient...
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#1Eric J. Charles (UVA: University of Virginia)H-Index: 10
#2Gorav Ailawadi (UVA: University of Virginia)H-Index: 44
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#1James H. Mehaffey (University of Virginia Health System)H-Index: 12
#2Robert B. Hawkins (University of Virginia Health System)H-Index: 9
Last.Peter T. Hallowell (University of Virginia Health System)H-Index: 12
view all 6 authors...
Abstract Background Surgical outcomes are affected by socioeconomic status, yet these factors are poorly accounted for in clinical databases. We sought to determine if the Distressed Communities Index (DCI), a composite ranking by zip code that quantifies socioeconomic risk, was associated with long-term survival after bariatric surgery. Methods All patients undergoing Roux-en-Y gastric bypass (1985-2004) at a single institution were paired with DCI. Scores range from 0 (no distress) to 100 (sev...
1 CitationsSource
#1Eric J. Charles (UVA: University of Virginia)H-Index: 10
#2Yikui Tian (UVA: University of Virginia)H-Index: 7
Last.Zequan Yang (UVA: University of Virginia)H-Index: 28
view all 9 authors...
Structured Abstract Objective Acute hyperglycemia during myocardial infarction worsens outcomes in part by inflammatory mechanisms. Pulsed ultrasound has anti-inflammatory potential in bone healing and neuromodulation. We hypothesized that pulsed ultrasound (pUS) would attenuate the hyperglycemic exacerbation of myocardial ischemia-reperfusion injury (IRI) via the cholinergic anti-inflammatory pathway. Methods Acute hyperglycemia was induced in wild-type C57BL6 (WT) or acetylcholine-receptor kno...
2 CitationsSource
#1Carrie A. Foster (VCU: Virginia Commonwealth University)
#2Eric J. Charles (UVA: University of Virginia)H-Index: 10
Last.R. Scott Jones (UVA: University of Virginia)H-Index: 20
view all 6 authors...
Background Postoperative pulmonary complications (PPCs; unplanned reintubation, postoperative pneumonia, and failure to liberate from mechanical ventilation within 48 hours), contribute significantly to increased rates of morbidity and mortality. Procedure type is an important factor that contributes risk in generalized PPC prediction models. The objective of this study was to develop and validate procedure-specific risk scores for the 6 procedures with the highest rates of PPCs. Study Design Am...
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#1James H. Mehaffey (UVA: University of Virginia)H-Index: 12
#2Robert B. Hawkins (UVA: University of Virginia)H-Index: 9
Last.R. Scott Jones (UVA: University of Virginia)H-Index: 20
view all 13 authors...
Background Socioeconomic status affects surgical outcomes, however these factors are not included in clinical quality improvement data and risk models. We performed a prospective registry analysis to determine if the Distressed Communities Index (DCI), a composite socioeconomic ranking by zip code, could predict risk-adjusted surgical outcomes and resource utilisation. Methods All patients undergoing surgery (n=44,451) in a regional quality improvement database (American College of Surgeons-Nati...
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#1Robert B. Hawkins (UVA: University of Virginia)H-Index: 9
#2Eric J. Charles (UVA: University of Virginia)H-Index: 10
Last.Margaret C. Tracci (UVA: University of Virginia)H-Index: 8
view all 8 authors...
Abstract Objective Several studies have demonstrated that socioeconomic factors may affect surgical outcomes. Analyses in vascular surgery have been limited by the availability of individual or community-level socioeconomic data. We sought to determine whether the Distressed Communities Index (DCI), a composite socioeconomic ranking by ZIP code, could predict short- and long-term outcomes for patients with peripheral artery disease. Methods All Virginia Quality Initiative patients (n = 2578) und...
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#1Adishesh K. Narahari (University of Virginia Health System)H-Index: 5
#2Ian O. Cook (University of Virginia Health System)H-Index: 1
Last.Gorav Ailawadi (University of Virginia Health System)H-Index: 44
view all 12 authors...
Abstract Objective National Institutes of Health (NIH) funding is becoming increasingly difficult to obtain. We sought to determine trends in NIH funding for cardiac surgeons hypothesizing they are at a disadvantage in obtaining funding due to intensive clinical demands. Methods Cardiac surgeons (adult/congenital) currently at the top 141 NIH-funded institutions were identified using institutional websites. The NIH funding history for each cardiac surgeon was queried using NIH Research Portfolio...
2 CitationsSource
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