Russell J. de Souza
McMaster University
EndocrinologyFructoseDiabetes mellitusMedicineMeta-analysis
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Publications 148
#1David J. A. JenkinsH-Index: 75
#2Viranda H. Jayalath (U of T: University of Toronto)H-Index: 11
Last. Phil Gold (McGill University)H-Index: 20
view all 24 authors...
AIMS When young, can we predict who will be the great innovators? For example, in medicine who will change clinical practice? We have therefore assessed whether the current academic excellence approach to medical school entrance would have captured previous great innovators in medicine, assuming that they should all have well fulfilled current entrance requirements. METHODS The authors assembled a list of 100 great medical innovators which was then approved, rejected or added to by a jury of 12 ...
#1Nitika Sanger (McMaster University)H-Index: 5
#2Balpreet Panesar (McMaster University)H-Index: 1
Last. M. Constantine Samaan (McMaster University)H-Index: 10
view all 14 authors...
Opioid use has reached an epidemic proportion in Canada and the United States that is mostly attributed to excess availability of prescribed opioids for pain. This excess in opioid use led to an increase in the prevalence of opioid use disorder (OUD) requiring treatment. The most common treatment recommendations include medication-assisted treatment (MAT) combined with psychosocial interventions. Clinical trials investigating the effectiveness of MAT, however, have a limited focus on effectivene...
#1Russell J. de Souza (McMaster University)H-Index: 38
#2Mahshid Dehghan (Population Health Research Institute)H-Index: 24
Last. Rafael DiazH-Index: 52
view all 28 authors...
BACKGROUND: The association of nuts with cardiovascular disease and deaths has been investigated mostly in Europe, the USA, and East Asia, with few data available from other regions of the world or from low- and middle-income countries. OBJECTIVE: To assess the association of nuts with mortality and cardiovascular disease (CVD). METHODS: The Prospective Urban Rural Epidemiology study is a large multinational prospective cohort study of adults aged 35-70 y from 16 low-, middle-, and high-income c...
#1Michael A. Zulyniak (McMaster University)H-Index: 11
#2Russell J. de Souza (McMaster University)H-Index: 38
Last. Padmaja Subbarao (U of T: University of Toronto)H-Index: 33
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Background: The global prevalence of childhood eczema has increased over the last few decades, with a marked increase in high-income countries. Differences in prevalence of childhood eczema between countries and ethnicities suggest that genetic and early modifiable environmental factors, such as dietary intake, may underlie this observation. To investigate the association between pregnancy diet and infant eczema in a consortium of prospective Canadian birth cohorts predominantly comprised of whi...
#1Meghan B. Azad (UM: University of Manitoba)H-Index: 26
#2Alyssa J. Archibald (UM: University of Manitoba)H-Index: 1
Last. Theo J. Moraes (U of T: University of Toronto)H-Index: 24
view all 13 authors...
Obesity often originates in early life, and is linked to excess sugar intake. Nonnutritive sweeteners (NNS) are widely consumed as “healthier” alternatives to sugar, yet recent evidence suggests NNS may adversely influence weight gain and metabolic health. The impact of NNS during critical periods of early development has rarely been studied. We investigated the effect of prenatal NNS exposure on postnatal adiposity and adipocyte development. In the CHILD birth cohort (N = 2298), we assessed mat...
#1Sandi Azab (Alexandria University)H-Index: 2
#2Russell J. de Souza (McMaster University)H-Index: 38
Last. Philip Britz-McKibbin (McMaster University)H-Index: 27
view all 9 authors...
Nutritional studies rely on various biological specimens for fatty acid (FA) determination, yet it is unclear how levels of serum non-esterified FA (NEFAs) correlate with other circulating lipid pools. Here, we used a high throughput method (< 4 min/sample) based on multisegment injection-non-aqueous-capillary electrophoresis-mass spectrometry (MSI-NACE-MS) to investigate whether specific serum NEFAs have utility as biomarkers of dietary fat intake in women. We first identified circulating NEFAs...
2 CitationsSource
#1Gita Wahi (McMaster University)H-Index: 10
#2Julie WilsonH-Index: 4
Last. Sonia S. Anand (McMaster University)H-Index: 82
view all 11 authors...
Background: Indigenous people in Canada carry a disproportionate burden of obesity and obesity-related diseases compared with non-Indigenous Canadians, which could be related to intergenerational trauma exposures. Implementing effective health promotion strategies to improve nutrition and physical activity behaviors during early childhood could be a strategy to mitigate the burden of intergenerational trauma exposures that have the potential to impact the trajectory to obesity and related compli...
#1Q. Liu (U of T: University of Toronto)H-Index: 2
#2Sabrina Ayoub-Charette (U of T: University of Toronto)H-Index: 2
Last. John L. SievenpiperH-Index: 46
view all 10 authors...
Background Sugar‐sweetened beverages are associated with hypertension. We assessed the relation of important food sources of fructose‐containing sugars with incident hypertension using a systematic...
2 CitationsSource
#1Sonia S. Anand (McMaster University)H-Index: 82
#2Sylvia Abonyi (U of S: University of Saskatchewan)H-Index: 9
Last. Ellen L. Toth (U of A: University of Alberta)H-Index: 25
view all 25 authors...
Summary Background Historical, colonial, and racist policies continue to influence the health of Indigenous people, and they continue to have higher rates of chronic diseases and reduced life expectancy compared with non-Indigenous people. We determined factors accounting for variations in cardiovascular risk factors among First Nations communities in Canada. Methods Men and women (n=1302) aged 18 years or older from eight First Nations communities participated in a population-based study. Quest...
#1Tauseef A. Khan (U of T: University of Toronto)H-Index: 9
#2Mobushra Tayyiba (U of T: University of Toronto)H-Index: 1
Last. John L. SievenpiperH-Index: 46
view all 10 authors...
Abstract Objective To determine the association of total and added fructose-containing sugars on cardiovascular (CVD) incidence and mortality. Methods MEDLINE, EMBASE and Cochrane Library were searched from January 1, 1980, to July 31, 2018. Prospective cohort studies assessing the association of reported intakes of total, sucrose, fructose and added sugars with CVD incidence and mortality in individuals free from disease at baseline were included. Risk estimates were pooled using the inverse va...
4 CitationsSource