Herta Flor
Heidelberg University
PsychologyNeurosciencePhysical therapyChronic painMedicine
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Publications 671
#1Jamila Andoh (Heidelberg University)H-Index: 9
#2Christopher Milde (Heidelberg University)H-Index: 5
Last. Herta Flor (Heidelberg University)H-Index: 98
view all 9 authors...
Phantom limb pain (PLP) has been associated with reorganization in primary somatosensory cortex (S1) and preserved S1 function. Here we examined if methodological differences in the assessment of cortical representations might explain these findings. We used functional magnetic resonance imaging during a virtual reality movement task, analogous to the classical mirror box task, in twenty amputees with and without PLP and twenty matched healthy controls. We assessed the relationship between task-...
#3Henrik Walter (Charité)H-Index: 69
Last. Uli BrombergH-Index: 21
view all 28 authors...
Imaging genetics offers the possibility of detecting associations between genotype and brain structure as well as function, with effect sizes potentially exceeding correlations between genotype and behavior. However, study results are often limited due to small sample sizes and methodological differences, thus reducing the reliability of findings. The IMAGEN cohort with 2000 young adolescents assessed from the age of 14 onwards tries to eliminate some of these limitations by offering a longitudi...
#1Mikkel ThøgersenH-Index: 3
#1Mikkel Thøgersen (Heidelberg University)H-Index: 1
Last. Laura Petrini (AAU: Aalborg University)H-Index: 11
view all 6 authors...
Phantom limb pain (PLP) may be relieved using a visual representation of an intact limb. However, patients with distorted (telescoped) phantoms seem unable to associate with visualizations of intact limbs. A virtual arm visualization was matched to the individual's phantom perception and controlled in an augmented reality (AR) intervention. Seven PLP participants with telescoped phantoms performed eight supervised home-based AR-training sessions (45 min each) within two weeks. The virtual arm wa...
1 CitationsSource
#1Zuo Zhang ('KCL': King's College London)H-Index: 2
#2Lauren Robinson ('KCL': King's College London)H-Index: 1
Last. Arun L.W. Bokde (Trinity College, Dublin)H-Index: 44
view all 36 authors...
Abstract Background Eating disorders are common in adolescence, devastating and strongly comorbid with other psychiatric disorders. Yet, little is known about their etiology to develop effective preventive measures. Methods Longitudinal assessments of disordered eating behaviors (DEBs; binge-eating, purging and dieting) and comorbid psychopathology were measured in 1,386 adolescents from the IMAGEN study. Development of DEBs and associated mental health problems were investigated by comparing pa...
#1Srinivasa N. RajaH-Index: 55
#2Daniel B. CarrH-Index: 72
Last. Kathleen A. SlukaH-Index: 70
view all 16 authors...
#1Amirhossein Modabbernia (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 25
#3Avi Reichenberg (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 9
Last. Andreas Becker (GAU: University of Göttingen)H-Index: 23
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Adolescence is a period of major brain reorganization shaped by biologically timed and by environmental factors. We sought to discover linked patterns of covariation between brain structural development and a wide array of these factors by leveraging data from the IMAGEN study, a longitudinal population-based cohort of adolescents. Brain structural measures and a comprehensive array of non-imaging features (relating to demographic, anthropometric, and psychosocial characteristics) were available...
#1Nicholas Judd (KI: Karolinska Institutet)
#2Bruno Sauce (KI: Karolinska Institutet)H-Index: 10
Last. Corinna Insensee (University Medical Center)
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Genetic factors and socioeconomic status (SES) inequalities play a large role in educational attainment, and both have been associated with variations in brain structure and cognition. However, genetics and SES are correlated, and no prior study has assessed their neural associations independently. Here we used a polygenic score for educational attainment (EduYears-PGS), as well as SES, in a longitudinal study of 551 adolescents to tease apart genetic and environmental associations with brain de...
#1Tamar R. Makin (UCL: University College London)H-Index: 21
#2Herta Flor (UMA: University of Mannheim)H-Index: 98
Abstract Following arm amputation the region that represented the missing hand in primary somatosensory cortex (S1) becomes deprived of its primary input, resulting in changed boundaries of the S1 body map. This remapping process has been termed ‘reorganisation’ and has been attributed to multiple mechanisms, including increased expression of previously masked inputs. In a maladaptive plasticity model, such reorganisation has been associated with phantom limb pain (PLP). Brain activity associate...
#1Han Bossier (UGent: Ghent University)H-Index: 2
#2Sanne Roels (UGent: Ghent University)H-Index: 7
Last. Antoine Grigis (Université Paris-Saclay)H-Index: 3
view all 25 authors...
Abstract Replicating results (i.e. obtaining consistent results using a new independent dataset) is an essential part of good science. As replicability has consequences for theories derived from empirical studies, it is of utmost importance to better understand the underlying mechanisms influencing it. A popular tool for non-invasive neuroimaging studies is functional magnetic resonance imaging (fMRI). While the effect of underpowered studies is well documented, the empirical assessment of the i...
1 CitationsSource
#1A. Galinowski (Paris V: Paris Descartes University)H-Index: 15
#2Ruben Miranda (Paris V: Paris Descartes University)H-Index: 5
Last. Jean-Luc Martinot (Paris V: Paris Descartes University)H-Index: 19
view all 43 authors...