Patrick J. Tighe
University of Florida
SurgeryPhysical therapyPerioperativeAnesthesiaMedicine
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Publications 108
#1L. Zhou (UA: University of Arizona)H-Index: 2
#2Sandipan Bhattacharjee (UA: University of Arizona)H-Index: 8
Last. Wei-Hsuan Lo-Ciganic (UF: University of Florida)H-Index: 13
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BACKGROUND AND AIMS Little is known about opioid and gabapentinoid (OPI-GABA) use duration and dose patterns' associations with adverse outcomes risks. We examined associations between OPI-GABA dose and duration trajectories and subsequent drug overdose. DESIGN Retrospective cohort study. SETTING US Medicare. PARTICIPANTS Using a 5% sample (2011-2016), we identified 71,005 fee-for-service Medicare beneficiaries with fibromyalgia, low back pain, neuropathy, and/or osteoarthritis initiating OPIs a...
#1Xinlei Mi (Columbia University)H-Index: 2
#2Patrick J. Tighe (UF: University of Florida)H-Index: 15
Last. Baiming Zou (UNC: University of North Carolina at Chapel Hill)
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Deep Treatment Learning (deepTL), a robust yet efficient deep learning-based semiparametric regression approach, is proposed to adjust the complex confounding structures in comparative effectiveness analysis of observational data, e.g. electronic health record (EHR) data, in which complex confounding structures are often embedded. Specifically, we develop a deep learning neural network with a score-based ensembling scheme for flexible function approximation. An improved semiparametric procedure ...
Current day pain assessment methods rely on patient self-report or by an observer like the Intensive Care Unit (ICU) nurses. Patient self-report is subjective to the individual and suffers due to poor recall. Pain assessment by manual observation is limited by the number of administrations per day and staff workload. Previous studies showed the feasibility of automatic pain assessment by detecting Facial Action Units (AUs). Pain is observed to be associated with certain facial action units (AUs)...
#1Tyler J. Loftus (University of Florida Health)H-Index: 11
#2Amanda C. Filiberto (University of Florida Health)H-Index: 2
Last. Gilbert R. Upchurch (University of Florida Health)H-Index: 2
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Surgeons perform two primary tasks: operating and engaging patients and caregivers in shared decision-making. Human dexterity and decision-making are biologically limited. Intelligent, autonomous machines have the potential to augment or replace surgeons. Rather than regarding this possibility with denial, ire, or indifference, surgeons should understand and steer these technologies. Closer examination of surgical innovations and lessons learned from the automotive industry can inform this proce...
#1Anis DavoudiH-Index: 7
Last. Parisa RashidiH-Index: 2
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Critical care patients experience varying levels of pain during their stay in the intensive care unit, often requiring administration of analgesics and sedation. Such medications generally exacerbate the already sedentary physical activity profiles of critical care patients, contributing to delayed recovery. Thus, it is important not only to minimize pain levels, but also to optimize analgesic strategies in order to maximize mobility and activity of ICU patients. Currently, we lack an understand...
#1Florenc DemroziH-Index: 1
Last. Parisa RashidiH-Index: 2
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Pain and physical function are both essential indices of recovery in critically ill patients in the Intensive Care Units (ICU). Simultaneous monitoring of pain intensity and patient activity can be important for determining which analgesic interventions can optimize mobility and function, while minimizing opioid harm. Nonetheless, so far, our knowledge of the relation between pain and activity has been limited to manual and sporadic activity assessments. In recent years, wearable devices equippe...
#1Patrick J. Tighe (UF: University of Florida)H-Index: 15
#2Bharadwaj Sannapaneni (UF: University of Florida)
Last. Parisa Rashidi (UF: University of Florida)H-Index: 2
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OBJECTIVE: Recent efforts to update the definitions and taxonomic structure of concepts related to pain have revealed opportunities to better quantify topics of existing pain research subject areas. METHODS: Here, we apply basic natural language processing (NLP) analyses on a corpus of >200,000 abstracts published on PubMed under the medical subject heading (MeSH) of "pain" to quantify the topics, content, and themes on pain-related research dating back to the 1940s. RESULTS: The most common ste...
#1Patrick J. Tighe (UF: University of Florida)H-Index: 15
#2Michael L. Kent (Duke University)H-Index: 45
Last. W. Michael Hooten (Mayo Clinic)H-Index: 33
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#1Yan Li (UF: University of Florida)H-Index: 6
#2Chris Delcher (UK: University of Kentucky)H-Index: 12
Last. Almut G. Winterstein (UF: University of Florida)H-Index: 24
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The recent opioid prescribing guideline cautions about the concomitant prescribing of opioids and skeletal muscle relaxants (SMRs) given the additive central nervous system depressant effect. However, the clinical relevance remains unclear. In this retrospective cohort study, we compared the risk of opioid overdose associated with concomitant use of opioids and SMRs vs. opioid use alone. Adjusted hazard ratios were 1.09 (95% confidence interval (CI), 0.74-1.62) and 1.26 (95% CI, 1.00-1.58) in th...
1 CitationsSource
#1Faraj W. Abdallah (Ottawa Hospital Research Institute)H-Index: 25
#1Faraj W. Abdallah (Ottawa Hospital Research Institute)H-Index: 7
Last. Colin J. L. McCartney (Ottawa Hospital Research Institute)H-Index: 1
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OBJECTIVE: The relationship between preexisting osteoarthritic pain and subsequent post-total knee arthroplasty (TKA) pain is not well defined. This knowledge gap makes diagnosis of post-TKA pain and development of management plans difficult and may impair future investigations on personalized care. Therefore, a set of diagnostic criteria for identification of acute post-TKA pain would inform standardized management and facilitate future research. METHODS: The Analgesic, Anesthetic, and Addictio...