Dirk Habedank
Publications 29
Background The ventilatory anaerobic threshold (VO2@AT) has been used in preoperative risk assessment and rehabilitation for many years. Our aim was to determine the interobserver variability of AT using cardiopulmonary exercise (CPET) data from a large epidemiological study (SHIP, Study of Health in Pomerania).
#1Ralf EwertH-Index: 32
#2Till IttermannH-Index: 26
Last.Kovács G (Medical University of Graz)H-Index: 17
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Background Systemic sclerosis (SSc) is a severe rheumatic disease of the interstitial tissue, in which heart and lung involvement can lead to disease-specific mortality. Our study tests the hypothesis that in addition to established prognostic factors, cardiopulmonary exercise testing (CPET) parameters, particularly peak oxygen uptake (peakVO2) and ventilation/carbon dioxide (VE/VCO2)-slope, can predict survival in patients with SSc.
#1Dirk HabedankH-Index: 11
#2Christian F. OpitzH-Index: 30
Last.Ralf EwertH-Index: 1
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We hypothesized that the slope of relation ventilation to carbon dioxide output (V’E/V’CO2-slope) could be predictive already during the very first days after submassive pulmonary embolism (PE) to right ventricular systolic pressure (RVsys by echocardiography) after 6 months. We evaluated 21 hemodynamically stable patients at admittance, at days 3, 7, 90, and 180 by cardiopulmonary exercise testing and echocardiography. V’E/V’CO2-slope (48.4 ± 10.8) decreased within the first week (43.0 ± 9.8 at...
#1Martin Stockburger (Charité)H-Index: 13
#2Eduardo de TeresaH-Index: 4
Last.Uwe K.H. WiegandH-Index: 2
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Aims Previous studies showed unfavourable effects of right ventricular (RV) pacing. Ventricular pacing (VP), however, is required in many patients with atrioventricular (AV) block. The PREVENT-HF study explored left ventricular (LV) remodelling during RV vs. biventricular (BIV) pacing in AV block without advanced heart failure. The pre-specified PREVENT-HF German Substudy examined exercise capacity and N-terminal pro-brain natriuretic peptide (NT-proBNP). Methods and results Patients with expect...
1 CitationsSource
#1Dirk HabedankH-Index: 11
#2F. Joachim MeyerH-Index: 16
Last.Ralf Ewert (University of Greifswald)H-Index: 21
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Background Respiratory muscle (RM) function predicts prognosis in non-cachectic patients with chronic heart failure (CHF). We hypothesized that weakness of RM (maximum inspiratory mouth occlusion pressure, Pimax) is a function of body mass index, and that outcome is more a function of BMI than of Pimax or ventilatory drive (P0.1).
17 CitationsSource
#1Florian Blaschke (Charité)H-Index: 9
#2Thomas Knaus (Charité)H-Index: 3
Last.Martin Stockburger (Charité)H-Index: 13
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Aims Mortality in chronic heart failure (CHF) patients with left bundle branch block (LBBB) is high. Cardiac resynchronization therapy (CRT) reduces symptoms and mortality in CHF patients with LBBB. Whether CRT promotes or prevents ventricular tachycardia (VT)/ventricular fibrillation (VF) remains controversial, however. Therefore, we aimed to analyse arrhythmia-related CRT effects and characterized the VT/VF incidence in CRT-defibrillator patients and matched controls with conventional implanta...
10 CitationsSource
10 CitationsSource
#1Martin Stockburger (Charité)H-Index: 13
#2Alice Krebs (Charité)H-Index: 7
Last.Rainer Dietz (Charité)H-Index: 63
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Evidence-based treatment for heart failure (HF) comprises beta-blockers, angiotensin converting enzyme inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists (ARA). Diuretics (DR) are prescribed in acute and chronic HF, but their impact on survival and ventricular tachyarrhythmias (VT/VF) is unclear. The present observational study aims to examine the influence of DR and ARA on survival and appropriate cardioverter/defibrillator (ICD) treatment episodes in routine ICD pa...
1 CitationsSource
Ziele: Die peripartale Kardiomyopathie (PPCM) ist eine seltene, potenziell lebensgefahrliche Erkrankung unklarer Genese, die bei primar gesunden Frauen im letzten Monat der Schwangerschaft oder bis funf Monate postpartum auftritt. Das Ziel dieser Studie war, ein umfassendes MR-Untersuchungsprotokoll bei Frauen mit PPCM zu evaluieren. Methode: Das standardisierte MR-Protokoll (1,5 T) umfasste SSFP-Cine-Sequenzen zur Volumenberechnung und Funktionsdiagnostik des rechten und linken Ventrikels, T2- ...
#1Tibor Szabó (Charité)H-Index: 6
#2Stephan von Haehling (Charité)H-Index: 45
Last.Wolfram Doehner (Charité)H-Index: 46
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Abstract Background In chronic heart failure (CHF), impaired insulin sensitivity (Si) is frequently observed. It is associated with symptomatic status and poor prognosis suggesting an intrinsic role of Si within CHF pathophysiology. HOmeostasis Model Assessment (HOMA), Fasting Insulin Resistance Index (FIRI), and QUick Insulin CheCK Index (QUICKI) are based on single-time fasting glucose and insulin assessment. Their value and discriminatory power in comparison to dynamic range assessment of Si ...
11 CitationsSource