Lisa K. Micklesfield
South African Medical Research Council
Publications 126
#1Sara K. Hanson (Emory University)
#2Richard J. Munthali (University of the Witwatersrand)H-Index: 5
Last.Aryeh D. Stein (Emory University)H-Index: 59
view all 8 authors...
Background Adolescence is a critical phase of human development that lays the foundation for health in later life. Of the 1.8 billion adolescents in the world, roughly 90% live in low and middle-income countries. Yet most longitudinal studies of adolescent physical activity, sedentary behavior, and sleep come from high-income countries. There is a need for a better understanding of these behaviors to inform obesity and chronic disease prevention strategies.
#1Asanda Mtintsilana (South African Medical Research Council)H-Index: 1
#2Lisa K. Micklesfield (South African Medical Research Council)H-Index: 19
Last.Julia H. Goedecke (South African Medical Research Council)H-Index: 5
view all 5 authors...
Cross-sectional studies in South Africa (SA) have shown that black SA women, despite being more insulin resistant, have less visceral adipose tissue (VAT) and more subcutaneous adipose tissue (SAT) than white women. This study aimed to investigate whether baseline and/or change in body fat and its distribution predict type 2 diabetes (T2D) risk in middle-aged black SA women, 13 years later. We studied 142 black SA women who are the caregivers of the Birth-to-Twenty plus cohort, and who had norma...
#1Oluwatosin Ayeni (University of the Witwatersrand)H-Index: 3
#2Shane A. Norris (University of the Witwatersrand)H-Index: 30
Last.Lisa K. Micklesfield (University of the Witwatersrand)H-Index: 19
view all 16 authors...
#1Catherine E. Draper (UCT: University of Cape Town)H-Index: 15
#2Simone A. Tomaz (UCT: University of Cape Town)H-Index: 4
Last.E V Lambert (UCT: University of Cape Town)H-Index: 16
view all 7 authors...
Background. Healthy Active Kids South Africa (HAKSA) Report Cards were produced in 2007, 2010, 2014 and 2016. Objective. The 2018 Report Card aims to report on the latest available evidence relating to the physical activity (PA), nutrition and body composition of South African (SA) children and adolescents. Methods. A review was conducted using the following databases: PubMed; Africa Journals Online; and Africa-Wide (EBSCOhost). Articles published from January 2016 to September 2018 were include...
#1Catherine E. DraperH-Index: 15
#2Simone A. TomazH-Index: 4
Last.Sally WykeH-Index: 37
view all 8 authors...
Rising levels of obesity in South Africa require innovation in community-level lifestyle change programmes. Our aim was to co-develop Impilo neZenkolo (‘Health through Faith’), a healthy lifestyle programme for low-income, black South Africans delivered through churches, and evaluate its feasibility, acceptability and potential effectiveness. In the first phase we developed programme materials with church members. In the second phase we trained lay leaders to deliver the programme and assessed f...
#1Engelbert A. Nonterah (UU: Utrecht University)H-Index: 4
#2Palwende R Boua (University of the Witwatersrand)
Last.Nigel J. Crowther (University of the Witwatersrand)H-Index: 28
view all 27 authors...
Background Studies on the determinants of carotid intima‐media thickness (CIMT), a marker of sub‐clinical atherosclerosis, mostly come from white, Asian, and diasporan black populations. We present...
#1Tinashe Chikowore (National Health Laboratory Service)H-Index: 1
#2Venesa Sahibdeen (National Health Laboratory Service)H-Index: 2
Last.Zané Lombard (National Health Laboratory Service)H-Index: 11
view all 7 authors...
Abstract Aim To evaluate the association between loss-of-function (LOF) PCSK9 variants (A433T/rs28362263 and C679X/rs28362286) and biomarkers of cardiometabolic risk, specifically fasting glucose and low density lipoprotein cholesterol (LDL-C) concentrations. Methods Our study comprised 757 male and female black South African adolescents (mean age 18.0 ± 0.5 years) who are part of the Birth to Twenty Plus Cohort and had been genotyped for the two above-mentioned variants. Anthropometric measures...
#1Yingxu Zeng (Umeå University)
#2Asanda Mtintsilana (University of the Witwatersrand)H-Index: 1
Last.Elin Chorell (Umeå University)H-Index: 7
view all 6 authors...
Abstract Background South Africa (SA) has the highest global projected increase in diabetes risk. Factors typically associated with insulin resistance and type 2 diabetes risk in Caucasians are not significant correlates in black African populations. Therefore, we aimed to identify circulating metabolite patterns that predict type 2 diabetes development in this high-risk, yet understudied SA population. Methods We conducted a prospective cohort study in black SA women with normal glucose toleran...
#1Asanda MtintsilanaH-Index: 1
Last.Julia H. GoedeckeH-Index: 30
view all 8 authors...
The dietary inflammatory index (DII®), a validated tool used to measure the inflammatory potential of the diet, has been associated with metabolic disorders in various settings, but not in African populations. The aim of this study was to investigate whether the DII is associated with markers of type 2 diabetes (T2D) risk, and if this association is mediated by adiposity and/or low-grade inflammation, in black South Africa women. Energy-adjusted-DII (E-DII) scores were calculated in 190 women (m...