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Konrad Stawiski
Medical University of Łódź
15Publications
3H-index
30Citations
Publications 15
Newest
#1Magdalena Zakrzewska (Medical University of Łódź)H-Index: 12
#2Renata Gruszka (Medical University of Łódź)H-Index: 1
Last.Krzysztof Zakrzewski (Memorial Hospital of South Bend)H-Index: 12
view all 9 authors...
The understanding of the molecular biology of pediatric neuronal and mixed neuronal-glial brain tumors is still insufficient due to low frequency and heterogeneity of those lesions which comprise several subtypes presenting neuronal and/or neuronal-glial differentiation. Important is that the most frequent ganglioglioma (GG) and dysembryoplastic neuroepithelial tumor (DNET) showed limited number of detectable molecular alterations. In such cases analyses of additional genomic mechanisms seem to ...
#1Beata Małachowska (Medical University of Łódź)H-Index: 7
#2Bartłomiej Tomasik (Medical University of Warsaw)H-Index: 6
Last.Wojciech Fendler (Harvard University)H-Index: 19
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Abstract Background MicroRNAs (miRNAs) were hypothesized to be robust and easy to measure biomarkers of radiation exposure which led to multiple studies in various clinical and experimental scenarios. We sought to identify evolutionary conserved, radiation-induced circulating miRNAs through a multi-species, integrative systematic review, and meta-analysis of miRNAs in radiation. Methods The systematic review was registered in the PROSPERO database (ID: XXX). We downloaded a list of studies with ...
Head and neck squamous cell carcinomas (HNSCCs) contribute to over 300,000 deaths every year worldwide. Although the survival rates have improved in some groups of patients, mostly due to new treatment options and the increasing percentage of human papillomavirus (HPV)-related cancers, local recurrences and second primary tumors remain a great challenge for the clinicians. Presently, there is no biomarker for patient surveillance that could help identify patients with HNSCC that are more likely ...
#1Ernest J. Bobeff (Medical University of Łódź)H-Index: 2
#2Bartłomiej J. Posmyk (Medical University of Łódź)
Last.Dariusz J. Jaskólski (Medical University of Łódź)H-Index: 10
view all 8 authors...
Objective Traumatic brain injury (TBI) remains a major cause of morbidity and mortality worldwide. The prognostic value of skull fracture (SF) remains to be clearly defined. To evaluate the need for neurosurgical intervention and determine the risk factors of conservative treatment failure (CTF), we retrieved from the hospital database the records of patients with SF after TBI. Methods We analyzed 146 consecutive patients (mean age: 49.8 ± 17.5 years) treated at the department of neurosurgery in...
#1Ernest J. BobeffH-Index: 2
#2Jan FortuniakH-Index: 4
Last.Dariusz J. JaskólskiH-Index: 10
view all 8 authors...
Background Traumatic brain injury (TBI) remains a life-threatening condition characterized by growing incidence worldwide, particularly in the aging population, in which the primary goal of treatment appears to be avoidance of chronic institutionalization. Methods To identify independent predictors of 30-day mortality or vegetative state in a geriatric population and calculate an intuitive scoring system, we screened 480 patients after TBI treated at a single department of neurosurgery over a 2-...
#1Magdalena Kotlicka-Antczak (Medical University of Łódź)H-Index: 9
#2Michał S. Karbownik (Medical University of Łódź)H-Index: 4
Last.Paolo Fusar-Poli (UNIPV: University of Pavia)H-Index: 62
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Abstract Objective The predictive accuracy of the Clinical High Risk criteria for Psychosis (CHR-P) regarding the future development of the disorder remains suboptimal. It is therefore necessary to incorporate refined risk estimation tools which can be applied at the individual subject level. The aim of the study was to develop an easy-to use, short refined risk estimation tool to predict the development of psychosis in a new CHR-P cohort recruited in European country with less established early...
#1Eirini-Stavroula Komseli (UoA: National and Kapodistrian University of Athens)H-Index: 3
#2Ioannis S. Pateras (UoA: National and Kapodistrian University of Athens)H-Index: 17
Last.Vassilis G. Gorgoulis (UoA: National and Kapodistrian University of Athens)H-Index: 45
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Senescence is a fundamental biological process implicated in various pathologies, including cancer. Regarding carcinogenesis, senescence signifies, at least in its initial phases, an anti-tumor response that needs to be circumvented for cancer to progress. Micro-RNAs, a subclass of regulatory, non-coding RNAs, participate in senescence regulation. At the subcellular level micro-RNAs, similar to proteins, have been shown to traffic between organelles influencing cellular behavior. The differentia...
#1Konrad Pagacz (Medical University of Łódź)H-Index: 1
#2Konrad Stawiski (Medical University of Łódź)H-Index: 3
Last.Wojciech Fendler (Harvard University)H-Index: 19
view all 5 authors...
#1Anna Puła (Medical University of Łódź)H-Index: 1
#2Konrad Stawiski (Medical University of Łódź)H-Index: 3
Last.Tadeusz Robak (Medical University of Łódź)H-Index: 55
view all 5 authors...
AbstractIbrutinib and idelalisib, B-cell receptor (BCR) signaling pathway inhibitors, have been recently approved for use against relapsed/refractory chronic lymphocytic leukemia (CLL). To assess the efficacy and safety of BCR pathway inhibitors in relapsed/refractory CLL, we conducted a systematic review and meta-analysis of five randomized controlled trials (1866 patients). Our study demonstrated that BCR pathway inhibitors significantly prolonged progression-free survival (PFS; pooled HR = 0....
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