Match!
Yu Yi Fu
Nan Kai University of Technology
1Publications
1H-index
30Citations
Publications 1
Newest
Published on Apr 1, 2008in Neuro-oncology10.09
Yu-Show Fu13
Estimated H-index: 13
(NYMU: National Yang-Ming University),
Yen Yang Lin1
Estimated H-index: 1
(NYMU: National Yang-Ming University)
+ 8 AuthorsYu Yi Fu1
Estimated H-index: 1
(Nan Kai University of Technology)
We tested the herbal extract 2,3,5,6-tetramethylpyrazine (TMP) for possible therapeutic efficacy against a glioma cell line and against gliomas transplanted into rat brains. In the cultured glioma cells, 50 μM TMP significantly inhibited glutamate-induced increase in intracellular calcium. Significant cell damage (30%) and proliferation suppression (10%), however, occurred only at higher concentrations (200–400 μM). Glioma- neuronal co-culturing resulted in significant neuronal damage and higher...
1