Marc Brisson
Laval University
Publications 101
#1Xiang Li (Imperial College London)
#2Christinah Mukandavire (Imperial College London)
Last.Tini Garske (Imperial College London)H-Index: 16
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Background The last two decades have seen substantial expansion of childhood vaccination programmes in low and middle income countries (LMICs). Here we quantify the health impact of these programmes by estimating the deaths and disability-adjusted life years (DALYs) averted by vaccination with ten antigens in 98 LMICs between 2000 and 2030. Methods Independent research groups provided model-based disease burden estimates under a range of vaccination coverage scenarios for ten pathogens: hepatiti...
#1Mélanie Drolet (Laval University)H-Index: 28
#2Élodie Bénard (Laval University)H-Index: 5
Last.Marc Brisson (Laval University)H-Index: 45
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Abstract Objectives To describe all published articles that have conducted comparisons of model-based effectiveness and cost-effectiveness results in the field of vaccination. Specific objectives were to 1) describe the methodologies used and 2) identify the strengths and limitations of the studies. Methods We systematically searched MEDLINE and Embase databases for studies that compared predictions of effectiveness and cost-effectiveness of vaccination of two or more mathematical models. We cat...
#1Philippe Lemieux-Mellouki (Laval University)H-Index: 4
#2Mélanie Drolet (Laval University)H-Index: 28
Last.Marc Brisson (Laval University)H-Index: 45
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Abstract Objective Previous HPV models have only included genital transmission, when evidence suggests that transmission between several anatomical sites occurs. We compared model predictions of population-level HPV vaccination effectiveness against genital HPV16 infection in women, using a 1) uni-site (genital site), and a 2) multi-site model (genital and one extragenital site). Methods We developed a uni-site and a multi-site deterministic HPV transmission model, assuming natural immunity was ...
#1Katharine J Looker (UoB: University of Bristol)H-Index: 18
#2Minttu M Rönn (Harvard University)H-Index: 6
Last.Marie-Claude Boily (Imperial College London)H-Index: 42
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Introduction We conducted two systematic reviews. Review 1 (R1) summarised evidence for the influence of HIV on HPV acquisition and clearance. Review 2 (R2) summarised the evidence for the influence of HPV on HIV acquisition. R1 is the first meta-analytic review to quantify the impact of HIV on HPV infection. R2 updates two earlier meta-analyses. Methods Both reviews were conducted according to PRISMA and MOOSE guidelines. We searched PubMed and Embase up to January 2017 for longitudinal studies...
#1Kate T. Simms (Cancer Council New South Wales)H-Index: 9
#2Jean-François Laprise (Laval University)H-Index: 11
Last.Karen Canfell (Cancer Council New South Wales)H-Index: 26
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Summary Background First generation bivalent and quadrivalent human papillomavirus (HPV) vaccines have been introduced in most developed countries. A next generation nonavalent vaccine (HPV9) has become available, just as many countries are considering transitioning from cytology-based to HPV-based cervical screening. A key driver for the cost-effectiveness of HPV9 will be a reduction in screen-detected abnormalities and surveillance tests. We aimed to evaluate the cost-effectiveness of HPV9 in ...